A new piece in the puzzle of the novel avian-origin influenza A (H7N9) virus

A new piece in the puzzle of the novel avian-origin influenza A (H7N9) virus
Title:
A new piece in the puzzle of the novel avian-origin influenza A (H7N9) virus
Other Titles:
Biology Direct
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Publication Date:
26 October 2013
Citation:
Lee et al.: A new piece in the puzzle of the novel avian-origin influenza A (H7N9) virus. Biology Direct 2013 8:26.
Abstract:
Reviewers: This article was reviewed by Prof Xiufan Liu (nominated by Dr Purificacion Lopez-Garcia) and Prof Sandor Pongor. Using phylogenetic analysis on newly available sequences, we characterize A/chicken/Jiangsu/RD5/2013(H10N9) as currently closest precursor strain for the NA segment in the novel avian-origin H7N9 virus responsible for an outbreak in China. We also show that the internal segments of this precursor strain are closely related to those of the presumed precursor for the HA segment, A/duck/Zhejiang/12/2011(H7N3), which indicates that the sources of both HA and NA donors for the reassortant virus are of regional and not migratory-bird origin and highlights the role of chicken already in the early reassortment events. Keywords: Avian influenza; Zoonotic infections; Phylogeny; Reassortment history
License type:
http://creativecommons.org/licenses/by/3.0/
Funding Info:
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ISSN:
1745-6150
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