Aris, A., Wahyuni, W. T., Putra, B. R., Hermawan, A., Nugroho, F. A. A., Seh, Z. W., & Khalil, M. (2025). Ultrasensitive non-enzymatic electrochemical detection of paraoxon-ethyl in fruit samples using 2D Ti3C2Tx/MWCNT-OH. Nanoscale, 17(5), 2554–2566. https://doi.org/10.1039/d4nr04060k
Abstract:
This study reports on the development of a highly sensitive non-enzymatic electrochemical sensor based on two-dimensional Ti3C2Tx/MWCNT-OH nanocomposite for the detection of the paraoxon-based pesticide. The synergistic effect between the Ti3C2Tx nanosheet and the functionalized multi-walled carbon nanotubes enhanced the sensor’s conductivity and catalytic activity. The nanocomposite demonstrated superior electrochemical and electroanalytical performance compared to the pristine Ti3C2Tx and MWCNT-OH in detecting paraoxon-ethyl in fruit samples (green and red grapes) with a linear response range from 0.1 to 100 μM, a low limit of detection (LOD) of 10 nM, limit of quantitation (LOQ) of 70 nM, and sensitivity of 0.957 µA μM-1 cm-2 at pH 8. Furthermore, the sensors maintained excellent selectivity and effectiveness in detecting paraoxon-ethyl even in the presence of various interferents, including diazinon, carbaryl, Fe2+, NO2−, NO3−, ascorbic acid, and glucose. The facile fabrication and enhanced sensing capabilities of the Ti₃C₂Tₓ/MWCNT-OH nanocomposite position it as a reliable, cost-effective, and sustainable alternative to conventional detection systems for monitoring pesticide residues in agricultural products.
License type:
Publisher Copyright
Funding Info:
This research / project is supported by the Singapore National Research Foundation - NRF Investigatorship
Grant Reference no. : NRF-NRFI09-0002