Mak, T.-M., Stegger, M., Mølbak, K., & Maurer-Stroh, S. (2025). Pathogen genomics for surveillance and outbreak investigations. In (Editor), Infectious Disease Emergencies: Preparedness and Response (pp. 270–288). NUS Press. https://doi.org/10.56159/emergencies-21
Abstract:
Advances in sequencing technology have enabled whole genome sequencing of microorganisms, allowing their rapid identification and characterisation and measure of relatedness to the highest resolution possible. This facilitates the tracking of pathogen evolution and spread, as well as the identification of variants of interest or concern. Pathogen genomics came into the spotlight with the COVID-19 pandemic. The unprecedented, close to real-time collection of SARS-CoV-2 whole genome sequences spurred rapid diagnostic development and informed outbreak response and surveillance strategies. This chapter provides an overview of the technical processes of sequencing and discusses the value and limitations of pathogen genomics in surveillance and outbreak response.
License type:
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Funding Info:
There was no specific funding for the research done