Levitskaya, Z., Ser, Z., Koh, H., Mei, W. S., Chee, S., Sobota, R. M., & Ghadessy, J. F. (2024). Engineering cell-free systems by chemoproteomic-assisted phenotypic screening. RSC Chemical Biology, 5(4), 372–385. https://doi.org/10.1039/d4cb00004h
Abstract:
Phenotypic screening identified drugs capable of improving the yeast lysate cell-free protein synthesis (CFPS) yield. A drug target gene identified using mass spectrometry proteomics was deleted to yield a yeast strain with higher productivity CFPS.
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Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Funding Info:
This research is supported by core funding from: A*STAR SIBER
Grant Reference no. : SIBER
This research / project is supported by the National Research Foundation - Shared Infrastructure Support (SIS) "Sing-mass" Scheme
Grant Reference no. :