PET-leveraged ALDH probe toward cancer stem cells

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Please use this identifier to cite or link to this item: https://oar.a-star.edu.sg/communities-collections/articles/22223

Title:

PET-leveraged ALDH probe toward cancer stem cells

Journal Title:

Journal of Materials Chemistry B

DOI:

DOI 10.1039/D5TB01253H

Publication URL:

https://doi.org/10.1039/d5tb01253h

Authors:

Ji Hyeon Kim, Bryan Yat Kit Hui, Jieun Lee, Kyeong-woo Lee, Jungryun Kim, Yujin Kim, Ming Hui Chua, Jianwei Xu, Min-Goo Lee, Xiaogang Liu, Jong Seung Kim

Keywords:

Publication Date:

19 August 2025

Citation:

Kim, J. H., Hui, B. Y. K., Lee, J., Lee, K., Kim, J., Kim, Y., Chua, M. H., Xu, J., Lee, M., Liu, X., & Kim, J. S. (2025). PET-leveraged ALDH probe toward cancer stem cells. Journal of Materials Chemistry B, 13(37), 11809–11820. https://doi.org/10.1039/d5tb01253h

Abstract:

AldeCou-1 enables aldehyde dehydrogenase (ALDH)-mediated PET turn-off fluorescence for live imaging of ALDH overexpressed cancer cells.

License type:

Publisher Copyright

Funding Info:

This work was supported by the National Research Foundation of Korea (NRF) funded by the Korea Ministry of Science and ICT (MSIT) (CRI project No. 2018R1A3B1052702, J.S.K. and RS-2024-00412235 J.H.K.). The authors would like to acknowledge funding support from the Ministry of Education, Singapore, through the Academic Research Fund Tier 2 (MOE-T2EP10222-0001), Singapore University of Technology and Design (SUTD) Kickstarter Initiative (grant number: SKI 2021_03_10).

Description:

URI:

https://oar.a-star.edu.sg/communities-collections/articles/22223

ISSN:

2050-750X
2050-7518

Collections:

Institute of Chemical and Engineering Sciences

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