Ionogels: recent advances in design, material properties and emerging biomedical applications

Ionogels: recent advances in design, material properties and emerging biomedical applications

Chemical Society Reviews

10.1039/D2CS00652A

http://dx.doi.org/10.1039/d2cs00652a

Xiaotong Fan, Siqi Liu, Zhenhua Jia, J. Justin Koh, Jayven Chee Chuan Yeo, Chen-Gang Wang, Nayli Erdeanna Surat'man, Xian Jun Loh, Jean Le Bideau, Chaobin He, Zibiao Li, Teck-Peng Loh

General Chemistry

16 March 2023

Fan, X., Liu, S., Jia, Z., Koh, J. J., Yeo, J. C. C., Wang, C.-G., Surat’man, N. E., Loh, X. J., Le Bideau, J., He, C., Li, Z., & Loh, T.-P. (2023). Ionogels: recent advances in design, material properties and emerging biomedical applications. Chemical Society Reviews, 52(7), 2497–2527. https://doi.org/10.1039/d2cs00652a

Ionic liquid (IL)-based gels (ionogels) have received considerable attention due to their unique advantages in ionic conductivity and their biphasic liquid–solid phase property. In ionogels, the negligibly volatile ionic liquid is retained in the interconnected 3D pore structure. On the basis of these physical features as well as the chemical properties of well-chosen ILs, there is emerging interest in the antibacterial and biocompatibility aspects. In this review, the recent achievements of ionogels for biomedical applications are summarized and discussed. Following a brief introduction of the various types of ILs and their key physicochemical and biological properties, the design strategies and fabrication methods of ionogels are presented by means of different confining networks. These sophisticated ionogels with diverse functions, aimed at biomedical applications, are further classified into several active domains, including wearable strain sensors, therapeutic delivery systems, wound healing and biochemical detections. Finally, the challenges and possible strategies for the design of future ionogels by integrating materials science with a biological interface are proposed

Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

This research is supported by core funding from: Science and Engineering Research Council (SERC) - Central Research Fund
Grant Reference no. : NA

This research / project is supported by the Ministry of Education - AcRF Tier 1 grants
Grant Reference no. : RT14/20

This research / project is supported by the A*STAR - MTC Individual Research Grant
Grant Reference no. : M21K2c0114

This research / project is supported by the A*STAR - MTC Programmatic Funding
Grant Reference no. : M22K9b0049

https://oar.a-star.edu.sg/communities-collections/articles/19394

0306-0012
1460-4744

Institute of Sustainability for Chemicals, Energy and Environment