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23 Oct 2025
BMRC
Bioinformatics Institute
Allosteric solution to the problems of undruggable targets, drug toxicity, and emerging resistance
(Pending publish)
Wei-Ven Tee,
Igor N. Berezovsky
Current Opinion in Structural Biology
11 Jun 2025
BMRC
Bioinformatics Institute
Designing Structure-specific and Switchable Allosteric Effectors for GPCRs Based on the Causality and Energetics of Inherent Signaling
(Pending publish)
Bingxue Dong,
Wei-Ven Tee,
Igor N. Berezovsky
Journal of Molecular Biology
14 May 2025
BMRC
Bioinformatics Institute
Sequence and Structure at Play in Designing Allosteric Drugs and Alleviating the Drug Resistance
(Pending publish)
Wei-Ven Tee,
Raechell,
Enrico Guarnera,
Igor N. Berezovsky
Journal of Molecular Biology
26 Sep 2024
BMRC
Bioinformatics Institute
Toward the Design of Allosteric Effectors: Gaining Comprehensive Control of Drug Properties and Actions
Wei-Ven Tee,
Sylvester J. M. Lim,
Igor N. Berezovsky
Journal of Medicinal Chemistry
15 Sep 2022
BMRC
Bioinformatics Institute
AlloMAPS 2: allosteric fingerprints of the AlphaFold and Pfam-trRosetta predicted structures for engineering and design
Zhen Wah Tan,
Wei-Ven Tee,
Enrico Guarnera,
Igor N Berezovsky
Nucleic Acids Research
12 Sep 2020
BMRC
Bioinformatics Institute
Disorder driven allosteric control of protein activity
Wei-Ven Tee,
Enrico Guarnera,
Igor N Berezovsky
Current Research in Structural Biology
12 Jul 2019
BMRC
Bioinformatics Institute
On the Allosteric Effect of nsSNPs and the Emerging Importance of Allosteric Polymorphism
Wei-Ven Tee,
Enrico Guarnera,
Igor N. Berezovsky
Journal of Molecular Biology
26 Oct 2018
BMRC
Bioinformatics Institute
AlloMAPS: allosteric mutation analysis and polymorphism of signaling database
Zhen Wah Tan,
Wei-Ven Tee,
Enrico Guarnera,
Lauren Booth,
Igor N. Berezovsky
Nucleic Acids Research
18 Jun 2018
BMRC
Bioinformatics Institute
Reversing allosteric communication: From detecting allosteric sites to inducing and tuning targeted allosteric response
Wei-Ven Tee,
Enrico Guarnera,
Igor N. Berezovsky
PLoS Computational Biology
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