Teo, L. T. K., Juantuah-Kusi, N., Subramanian, G., Sampath, P. (2025). Psoriasis Treatments: Emerging Roles and Future Prospects of MicroRNAs. Non-Coding RNA, 11(1), 16. https://doi.org/10.3390/ncrna11010016
Abstract:
Psoriasis, a widespread and chronic inflammatory skin disorder, is marked by its persistence and the lack of a definitive cure. The pathogenesis of psoriasis is increasingly understood, with ongoing research highlighting the intricate interplay of genetic, immunological, and environmental factors. Recent advancements have illuminated the pivotal role of microRNAs in orchestrating complex processes in psoriasis and other hyperproliferative skin diseases. This narrative review highlights the emerging significance of miRNAs as key regulators in psoriasis pathogenesis and examines their potential as therapeutic targets. We discuss current treatment approaches and the promising future of miRNAs as next-generation therapeutic agents for this condition.
License type:
Attribution 4.0 International (CC BY 4.0)
Funding Info:
This research / project is supported by the NATIONAL MEDICAL RESEARCH COUNCIL - Open Fund - Young Individual Research Grant (OF-YIRG)
Grant Reference no. : MOH-001351(MOH-OFYIRG23jan-0013)