Hyaluronic acid–green tea catechin conjugates as a potential therapeutic agent for rheumatoid arthritis

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Hyaluronic acid–green tea catechin conjugates as a potential therapeutic agent for rheumatoid arthritis
Title:
Hyaluronic acid–green tea catechin conjugates as a potential therapeutic agent for rheumatoid arthritis
Other Titles:
RSC Advances
Publication Date:
19 April 2021
Citation:
Lee, F., Bae, K. H., Ng, S., Yamashita, A., & Kurisawa, M. (2021). Hyaluronic acid–green tea catechin conjugates as a potential therapeutic agent for rheumatoid arthritis. RSC Advances, 11(24), 14285–14294. doi:10.1039/d1ra01491a
Abstract:
Macromolecular HA–EGCG conjugates undergo targeted internalization by CD44-overexpressing fibroblast-like synoviocytes and subsequently cause H2O2-induced cell death and inhibition of IL-6 secretion, thereby suppressing the progression of arthritis.
License type:
Attribution 4.0 International (CC BY 4.0)
Funding Info:
This research is supported by core funding from: BMRC
Grant Reference no. : SC19-R0004
Description:
ISSN:
2046-2069