Amalina Binte Ebrahim Attia, Renzhe Bi, Kapil Dev, Yao Du, Malini Olivo. “Clinical noninvasive imaging and spectroscopic tools for dermatological applications: review of recent progress,” Translational Biophotonics. 2020. DOI: 10.1002/tbio.202000010
Abstract:
Dermatologists mainly entrust visual clinical examinations in conjunction with histopathology for an informed skin condition diagnosis, which is invasive and not adequate to assess skin conditions still present in subcutaneous skin layers. With emerging complementary imaging and spectroscopic technologies currently available, the assessment of skin conditions is more accessible than before. This review article will cover these technologies including: photoacoustic imaging, reflectance confocal microscopy, multiphoton microscopy, optical coherence tomography and confocal Raman spectroscopy. The basic concepts of these technologies and their configurations will be touched on, together with their limitations and future directions. The review article will discuss how these technologies are utilized for cutaneous applications, examining studies accomplished either in vivo on humans or on ex vivo human specimens.
License type:
Attribution 4.0 International (CC BY 4.0)
Funding Info:
This research is supported by core funding from: Singapore Bioimaging Consortium
Grant Reference no. :
This research / project is supported by the Agency for Science, Technology and Research - Industry Alignment Fund Pre-positioning Programme
Grant Reference no. : H19H6a0025