One-pot Suzuki–Heck relay to prepare industrially valuable iniates using the Pd–Cy*Phine catalyst system

One-pot Suzuki–Heck relay to prepare industrially valuable iniates using the Pd–Cy*Phine catalyst system
Title:
One-pot Suzuki–Heck relay to prepare industrially valuable iniates using the Pd–Cy*Phine catalyst system
Other Titles:
Catalysis Science & Technology
Keywords:
Publication Date:
30 August 2017
Citation:
Das, U. K.; Clement, R.; Johannes, C. W.; Robins, E. G.; Jong, H.; Baker, R. T., One-pot Suzuki–Heck relay to prepare industrially valuable intermediates using the Pd-Cy*Phine catalyst system. Catalysis Science & Technology 2017, 7 (20), 4599-4603.
Abstract:
A rare example of a one-pot, palladium-catalyzed Suzuki–Heck sequence has been developed with applicability to APIs and organoelectronic materials. High throughput screening was used to expedite development and survey strategies. Interchangeability of the coupling partners and the avoidance of intermediate isolation gives operational flexibility, which can be used to improve process efficiency and suppress by-product formation.
License type:
PublisherCopyrights
Funding Info:
This work was funded by the A*STAR Institute of Chemical and Engineering Sciences (ICES), the A*STAR Singapore Bio-imaging Consortium (SBIC) and the Canada Research Chairs program.
Description:
ISSN:
2044-4753
2044-4761
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