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8 Jun 2022
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BMRC
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Institute of Molecular and Cell Biology
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Epigenetic Regulation of Inflammatory Signaling and Inflammation-Induced Cancer
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Shawn Ying Xuan Tan,
Jieqiong Zhang,
Wee-Wei Tee
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Frontiers in Cell and Developmental Biology
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19 May 2022
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BMRC
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Bioprocessing Technology Institute
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An allied reprogramming, selection, expansion and differentiation platform for creating hiPSC on microcarriers
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Alan Tin Lun Lam,
Valerie Ho,
Svetlan Vassilev,
Shaul Reuveny,
Steve Kah Weng Oh
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Cell Proliferation
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15 Feb 2022
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BMRC
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Institute of Molecular and Cell Biology
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Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
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Jia Tong Loh,
Bin Zhang,
Joey Kay Hui Teo,
Ruenn Chai Lai,
Andre Boon Hwa Choo,
Kong-Peng Lam,
Sai Kiang Lim
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Cytotherapy
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2 Dec 2021
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BMRC
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Institute of Molecular and Cell Biology
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A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers
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A. Fatehullah,
Y. Terakado,
S. Sagiraju,
T. L. Tan,
T. Sheng,
S. H. Tan,
K. Murakami,
Y. Swathi,
N. Ang,
R. Rajarethinam,
T. Ming,
P. Tan,
B. Lee,
N. Barker
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Nature Cell Biology
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31 Aug 2021
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BMRC
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Institute of Molecular and Cell Biology
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Mast cells: Therapeutic targets for COVID ‐19 and beyond
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Hiu Yan Lam,
Vinay Tergaonkar,
Alan Prem Kumar,
Kwang Seok Ahn
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IUBMB Life
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7 May 2021
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BMRC
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Institute of Molecular and Cell Biology
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Retinoic acid induces NELFA‐mediated 2C‐like state of mouse embryonic stem cells associates with epigenetic modifications and metabolic processes in chemically defined media
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Yanqiu Wang,
Qin Na,
Xihe Li,
Wee‐Wei Tee,
Baojiang Wu,
Siqin Bao
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Cell Proliferation
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26 Feb 2021
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BMRC
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Bioprocessing Technology Institute
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Multiomics analyses of cytokines, genes, miRNA, and regulatory networks in human mesenchymal stem cells expanded in stirred microcarrier-spinner cultures
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Alan Tin-Lun Lam,
Alison P. Lee,
Premkumar Jayaraman,
Kah Yong Tan,
Deepak Raghothaman,
Hsueh Lee Lim,
He Cheng,
Lihan Zhou,
Andy Hee-Meng Tan,
Shaul Reuveny,
Steve Oh
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Stem Cell Research
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18 Feb 2021
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BMRC
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Institute of Molecular and Cell Biology
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Non-canonical roles of canonical telomere binding proteins in cancers
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Semih Can AKINCILAR,
Claire Hian Tzer Chan,
Qin Feng NG,
Kerem Fidan,
Vinay Tergaonkar
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Cellular and Molecular Life Sciences
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|
5 Feb 2021
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BMRC
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Institute of Bioengineering and Nanotechnology
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Novel live cell fluorescent probe for human-induced pluripotent stem cells highlights early reprogramming population
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Sandhya Sriram,
Nam-Young Kang,
Subha Subramanian,
Tannistha Nandi,
Samydurai Sudhagar,
Qiaorui Xing,
Gerine Jin-Ling Tong,
Allen Kuan-Liang Chen,
Thekkeparambil Chandrabose Srijaya,
Patrick Tan,
Yuin-Han Loh,
Young-Tae Chang,
Shigeki Sugii
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Stem Cell Research & Therapy
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|
4 Feb 2021
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BMRC
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Institute of Bioengineering and Nanotechnology
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CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells
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Smarajit Chakraborty,
Wee Kiat Ong,
Winifred W. Y. Yau,
Zhihong Zhou,
K. N. Bhanu Prakash,
Sue-Anne Toh,
Weiping Han,
Paul M. Yen,
Shigeki Sugii
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Stem Cell Research & Therapy
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|
11 Dec 2020
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BMRC
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Bioprocessing Technology Institute
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A Scalable Suspension Platform for Generating High-Density Cultures of Universal Red Blood Cells from Human Induced Pluripotent Stem Cells
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Jaichandran Sivalingam,
Yu SuE,
Zhong Ri Lim,
Alan T.L. Lam,
Alison P. Lee,
Hsueh Lee Lim,
Hong Yu Chen,
Hong Kee Tan,
Tushar Warrier,
Jing Wen Hang,
Nazmi B. Nazir,
Andy H.M. Tan,
Laurent Renia,
Yuin Han Loh,
Shaul Reuveny,
Benoit Malleret,
Steve K.W. Oh
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Stem Cell Reports
|
|
12 Nov 2020
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BMRC
|
Institute of Molecular and Cell Biology
|
ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation
|
Jin-Hui Hor,
Munirah Mohamad Santosa,
Valerie Jing Wen Lim,
Beatrice Xuan Ho,
Amy Taylor,
Zi Jian Khong,
John Ravits,
Yong Fan,
Yih-Cherng Liou,
Boon-Seng Soh,
Shi-Yan Ng
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Cell Death & Differentiation
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|
13 Dec 2019
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BMRC
|
Institute of Molecular and Cell Biology
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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
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Ekta Khattar,
Kyaw Ze Ya Maung,
Chen Li Chew,
Arkasubhra Ghosh,
Michelle Meng Huang Mok,
Pei Lee,
Jun Zhang,
Wei Hong Jeff Chor,
Gökhan Cildir,
Chelsia Qiuxia Wang,
Nur Khairiah Mohd-Ismail,
Desmond Wai Loon Chin,
Soo Chin Lee,
Henry Yang,
Yong-Jae Shin,
Do-Hyun Nam,
Liming Chen,
Alan Prem Kumar,
Lih Wen Deng,
Masahito Ikawa,
Jayantha Gunaratne,
Motomi Osato,
Vinay Tergaonkar
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Nature Communications
|
|
4 Jul 2019
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BMRC
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Bioprocessing Technology Institute
|
von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes
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Shengli Xu,
Jianxin Huo,
Yuhan Huang,
Melissa Aw,
Shuwen Chen,
Shiya Mak,
Lian Yee Yip,
Ying Swan Ho,
Sze Wai Ng,
Andy Hee-Meng Tan,
Alison Lee,
Xijun Ou,
Kong-Peng Lam
|
iSCIENCE
|
|
14 Dec 2018
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BMRC
|
Institute of Molecular and Cell Biology
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A Flow Cytometry‐Based Assay for High‐Throughput Detection and Quantification of Neutrophil Extracellular Traps in Mixed Cell Populations
|
Olga Zharkova,
Sen Hee Tay,
Hui Yin Lee,
Tripathi Shubhita,
Wei Yee Ong,
Aisha Lateef,
Paul Anthony MacAry,
Lina Hsiu Kim Lim,
John Edward Connolly,
Anna‐Marie Fairhurst
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Cytometry Part A
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|
5 Dec 2018
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BMRC
|
Institute of Molecular and Cell Biology
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Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
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Franklin L. Zhong,
Kim Robinson,
Daniel Eng Thiam Teo,
Kiat-Yi Tan,
Chrissie Lim,
Cassandra R. Harapas,
Chien-Hsiung Yu,
William H. Xie,
Radoslaw M. Sobota,
Veonice Bijin Au,
Richard Hopkins,
Andrea D'Osualdo,
John C. Reed,
John E. Connolly,
Seth L. Masters,
Bruno Reversade
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Journal of Biological Chemistry
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|
21 Sep 2018
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BMRC
|
Institute of Molecular and Cell Biology
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Overexpression of the nucleocapsid protein of Middle East respiratory syndrome coronavirus up-regulates CXCL10
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James Odame Aboagye,
Chow Wenn Yew,
Oi-Wing Ng,
Vanessa M. Monteil,
Ali Mirazimi,
Yee-Joo Tan
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Bioscience Reports
|
|
12 Sep 2018
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BMRC
|
Institute of Molecular and Cell Biology
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Distinct requirements of E2f4 versus E2f5 activity for multiciliated cell development in the zebrafish embryo
|
Yan Ling Chong,
Yiliu Zhang,
Feng Zhou,
Sudipto Roy
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Developmental Biology
|
|
14 Mar 2018
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BMRC
|
Institute of Molecular and Cell Biology
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Rapid production of pure recombinant actin isoforms in Pichia pastoris
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Tomoyuki Hatano,
Salvatore Alioto,
Emanuele Roscioli,
Saravanan Palani,
Scott T. Clarke,
Anton Kamnev,
Juan Ramon Hernandez-Fernaud,
Lavanya Sivashanmugam,
Bernardo Chapa-y-Lazo,
Alexandra M. E. Jones,
Robert C. Robinson,
Karuna Sampath,
Masanori Mishima,
Andrew D. McAinsh,
Bruce L. Goode,
Mohan K. Balasubramanian
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Journal of Cell Science
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|
8 Jan 2018
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BMRC
|
Institute of Molecular and Cell Biology
|
Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis
|
Lina Wang,
Zhaowei Tu,
Chao Liu,
Hongbin Liu,
Philipp Kaldis,
Zijiang Chen,
Wei Li
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Cell Death & Differentiation
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|
16 Nov 2017
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BMRC
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Institute of Molecular and Cell Biology
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Structural analyses unravel the molecular mechanism of cyclic di-GMP regulation of bacterial chemotaxis via a PilZ adaptor protein
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Xin-Fu Yan,
Lingyi Xin,
Jackie Tan Yen,
Yukai Zeng,
Shengyang Jin,
Qing Wei Cheang,
Rachel Andrea Chea Yuen Fong,
Keng-Hwee Chiam,
Zhao-Xun Liang,
Yong-Gui Gao
|
Journal of Biological Chemistry
|
|
25 Oct 2017
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BMRC
|
Institute of Molecular and Cell Biology
|
The vertebrate habenula
|
Suresh Jesuthasan
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Seminars in Cell & Developmental Biology
|
|
23 Oct 2017
|
BMRC
|
Institute of Molecular and Cell Biology
|
A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans
|
Rebecca S. Shapiro,
Alejandro Chavez,
Caroline B. M. Porter,
Meagan Hamblin,
Christian S. Kaas,
James E. DiCarlo,
Guisheng Zeng,
Xiaoli Xu,
Alexey V. Revtovich,
Natalia V. Kirienko,
Yue Wang,
George M. Church,
James J. Collins
|
Nature Microbiology
|
|
29 May 2015
|
BMRC
|
Experimental Drug Development Centre
|
Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport.
|
Hui Ting Toh,
CongBao Kang,
Neelagandan Kamariah,
Chi Li,
Kwanghee Baek,
Huiya Huang,
Carl White,
Sreekanth Rajan,
Minjoo Choi,
Quoc Toan Nguyen,
Hong Ye,
Gerhard Gruber,
Ho Sup Yoon
|
Scientific Reports
|
|
14 Nov 2014
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BMRC
|
Institute of Bioengineering and Nanotechnology
|
Robotic Cell Manipulation Using Optical Tweezers With Unknown Trapping Stiffness and Limited FOV
|
Xiang Li,
Chien Chern Cheah
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IEEE/ASME Transactions on Mechatronics
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|
23 Jul 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Toward stable gene expression in CHO cells
|
Mariati Mariati,
Esther Y.C Koh,
Jessna H.M. Yeo,
Steven C.L. Ho,
Yuansheng Yang
|
Bioengineered
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|
23 Jun 2014
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BMRC
|
Bioprocessing Technology Institute
|
Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells
|
Wan Ping Loh,
Bernard Loo,
Peiqing Zhang,
Dong-Yup Lee,
Yuansheng Yang,
Kong Peng Lam,
Lihan Zhou
|
Biotechnology Journal
|
|
31 May 2014
|
BMRC
|
Institute of Bioengineering and Nanotechnology
|
Robotic cell manipulation using optical tweezers with limited FOV
|
D. Sun,
X. Li,
C. C. Cheah,
X. Yan
|
2014 IEEE International Conference on Robotics and Automation (ICRA)
|
|
10 May 2014
|
BMRC
|
Bioprocessing Technology Institute
|
Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells
|
Mariati Mariati,
Jessna H. M. Yeo,
Esther Y. C. Koh,
Steven C. L. Ho,
Yuansheng Yang
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Biotechnology Progress
|
|
16 Apr 2014
|
BMRC
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Bioprocessing Technology Institute
|
Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells
|
Steven C. L. Ho,
Yuansheng Yang
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Biotechnology Letters
|
|
10 Dec 2013
|
BMRC
|
Institute of Bioengineering and Nanotechnology
|
A simple setpoint controller for dynamic manipulation of biological cells using optical tweezers
|
C. C. Cheah,
X. Li,
X. Yan,
D. Sun,
H. C. Liaw
|
2013 IEEE 52nd Annual Conference on Decision and Control (CDC)
|
|
9 Dec 2013
|
BMRC
|
Bioprocessing Technology Institute
|
An Internal Ribosome Entry Site (IRES) Mutant Library for Tuning Expression Level of Multiple Genes in Mammalian Cells
|
Esther Y. C. Koh,
Steven C. L. Ho,
Mariati Mariati,
Zhiwei Song,
Xuezhi Bi,
Muriel Bardor,
Yuansheng Yang
|
PLoS ONE
|
|
2 Oct 2013
|
BMRC
|
Institute of Bioengineering and Nanotechnology
|
Uncalibrated Vision-Based Control for Optical Manipulation of Microscopic Particles
|
X. Li,
C. C. Cheah
|
Proceedings of The 3rd IFTOMM International Synposium on Robotics and Mechatronics
|
|
19 Aug 2013
|
BMRC
|
Bioprocessing Technology Institute
|
Allantoin as a solid phase adsorbent for removing endotoxins
|
Vincent Vagenende,
Tim-Jang Ching,
Rui-Jing Chua,
Pete Gagnon
|
Journal of Chromatography A
|
|
5 Aug 2013
|
BMRC
|
Institute of Bioengineering and Nanotechnology
|
Optical manipulation of biological cell without measurement of cell velocity
|
C. C. Cheah,
X. Li,
X. Yan,
D. Sun
|
2013 13th IEEE Conference on Nanotechnology (IEEE-NANO)
|
|
5 Dec 2012
|
BMRC
|
Institute of Bioengineering and Nanotechnology
|
Observer based adaptive control for optical manipulation of cell
|
X. Li,
C. C. Cheah
|
2012 12th International Conference on Control Automation Robotics & Vision (ICARCV)
|
|
4 Dec 2012
|
BMRC
|
Institute of Molecular and Cell Biology
|
RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells (Pending publish)
|
Joanne Chia,
Germaine Goh,
Victor Racine,
Susanne Ng,
Pankaj Kumar,
Frederic Bard
|
Molecular Systems Biology
|