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21 Jan 2026
BMRC
Institute of Molecular and Cell Biology
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
Yafei Du,
Wenjing Wang,
Hui Chin Goh,
Thamil Selvan Vaiyapuri,
Anandhkumar Raju,
Yu-Chun Hsiao,
Cheng Chun Wang,
Vanisha Agrawal,
Noorul Farzana Mohideen,
Norhidayah Binte Mohd Mazian,
Feride Karatekin,
Wendy Kehan Wang,
Manikandan Lakshmanan,
Komal Gupta,
Han Chang,
Xavier Le Guezennec,
Frederic Bard,
Daniel S. W. Tan,
Vinay Tergaonkar,
Mien-Chie Hung,
Xiaogang Liu,
Wanjin Hong,
Gandhi T. K. Boopathy
Science Advances
25 Jun 2025
BMRC
Institute of Molecular and Cell Biology
Cracking the EGFR code: Cancer biology, resistance mechanisms, and future therapeutic frontiers
Yafei Du,
Feride Karatekin,
Wendy Kehan Wang,
Wanjin Hong,
Gandhi T.K. Boopathy
Pharmacological Reviews
1 Apr 2025
BMRC
Institute of Molecular and Cell Biology
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Reza Bayat Mokhtari,
Divyaleka Sampath,
Paige Eversole,
Melissa Ong Yu Lin,
Dmitriy A. Bosykh,
Gandhi T.K. Boopathy,
Aravind Sivakumar,
Cheng‐Chun Wang,
Ramesh Kumar,
Joe Yeong Poh Sheng,
Ellen Karasik,
Barbara A. Foster,
Han Yu,
Xiang Ling,
Wenjie Wu,
Fengzhi Li,
Zoë Weaver Ohler,
Christine F. Brainson,
David W. Goodrich,
Wanjin Hong,
Sayan Chakraborty
Advanced Science
18 Jan 2025
BMRC
Singapore Immunology Network
Plasticity of cell death pathways ensures GSDMD activation during Yersinia pseudotuberculosis infection
Felicia Hui Min Chan,
Hui Wen Yeap,
Zonghan Liu,
Safwah Nasuha Rosli,
Kay En Low,
Isabelle Bonne,
Yixuan Wu,
Shu Zhen Chong,
Kaiwen W. Chen
Cell Reports
27 Dec 2024
BMRC
Skin Research Lab
Citric acid is more effective than sodium thiosulfate in chelating calcium in a dissolution model of calcinosis
Kyle A. Burgess,
Richard E. P. Winpenny,
Alberto Saiani,
Aline F. Miller,
Ariane L. Herrick,
Rachel E. B. Watson
Scientific Reports
17 Dec 2024
BMRC
A*STAR Infectious Disease Labs
Sdd3 regulates the biofilm formation of Candida albicans via the Rho1-PKC-MAPK pathway
Li Mei Pang,
Guisheng Zeng,
Eve Wai Ling Chow,
Xiaoli Xu,
Ning Li,
Yee Jiun Kok,
Shu Chen Chong,
Xuezhi Bi,
Jiaxin Gao,
Chaminda Jayampath Seneviratne,
Yue Wang
mBio
19 Nov 2024
BMRC
Institute of Molecular and Cell Biology
Nuclear receptor-SINE B1 network modulates expanded pluripotency in blastoids and blastocysts
Ka Wai Wong,
Yingying Zeng,
Edison Tay,
Jia Hao Jackie Teo,
Nadia Omega Cipta,
Kiyofumi Hamashima,
Yao Yi,
Haijun Liu,
Tushar Warrier,
Minh T. N. Le,
Soon Chye Ng,
Qi-Jing Li,
Hu Li,
Yuin-Han Loh
Nature Communications
22 Jun 2024
BMRC
Bioinformatics Institute
HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes
Natasha Hui Jin Ng,
Soumita Ghosh,
Chek Mei Bok,
Carmen Ching,
Blaise Su Jun Low,
Juin Ting Chen,
Euodia Lim,
María Clara Miserendino,
Yaw Sing Tan,
Shawn Hoon,
Adrian Kee Keong Teo
Nature Communications
14 Aug 2023
BMRC
Genome Institute of Singapore
Multimodal metabolomics pinpoint new metabolic vulnerability in colorectal cancer
May Yin Lee,
Wai Leong Tam
Nature Metabolism
12 Aug 2023
BMRC
Skin Research Lab
IL-17–Mediated Downregulation of miR-101 Facilitates the Expression of EZH2 to Promote Epidermal Hyperplasia in Psoriasis
Shan Quah,
Gopinath M. Sundaram,
Gowtham Subramanian,
Candida Vaz,
Jonathan S.L. Tan,
Ramisa Fariha Kabir,
Jesslyn M.R. Ong,
Hazel H. Oon,
Colin Theng,
Prabha Sampath
Journal of Investigative Dermatology
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