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8 Nov 2024
BMRC
Bioprocessing Technology Institute
Real‐Time Adaptive Inline Acidification Enhances Continuous pH Control for Viral Inactivation
Jia Sheng Zach Lee,
Tan Dai Nguyen,
Zi Ying Zheng,
Wei Zhang,
Dan Liu
Biotechnology Journal
18 Oct 2024
BMRC
Bioprocessing Technology Institute
Thermal and pH stress dictate distinct mechanisms of monoclonal antibody aggregation
Kong Meng Hoi,
Kuin Tian Pang,
Corrine Wan,
Zi Ying Zheng,
Beiying Qiu,
Yuansheng Yang,
Zhang Wei,
Ying Swan Ho,
Ian Walsh,
Sean Chia
International Journal of Biological Macromolecules
11 Jul 2024
BMRC
Bioprocessing Technology Institute
Biomass specific perfusion rate as a control lever for the continuous manufacturing of biosimilar monoclonal antibodies from CHO cell cultures
Jiayu Leong,
Wen Qin Tang,
Jake Chng,
Wei Xuan Ler,
Norhaizat Abdul Manan,
Lyn Chiin Sim,
Zi Ying Zheng,
Wei Zhang,
Ian Walsh,
Gerben Zijlstra,
Maarten Pennings,
Say Kong Ng
Biotechnology Journal
25 Jan 2023
BMRC
Bioprocessing Technology Institute
Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step
Serene W. Chen,
Zi Ying Zheng,
Farouq Bin Mahfut,
Yuansheng Yang,
Masahiro Ogino,
Kazuo Okada,
Kohei Sato,
Wei Zhang
PLOS ONE
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