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12 Nov 2020
BMRC
Institute of Molecular and Cell Biology
ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation
Jin-Hui Hor,
Munirah Mohamad Santosa,
Valerie Jing Wen Lim,
Beatrice Xuan Ho,
Amy Taylor,
Zi Jian Khong,
John Ravits,
Yong Fan,
Yih-Cherng Liou,
Boon-Seng Soh,
Shi-Yan Ng
Cell Death & Differentiation
15 Oct 2020
BMRC
Institute of Molecular and Cell Biology
Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics
Kylie Su Mei Yong,
Zhisheng Her,
Sue Yee Tan,
Wilson Wei Sheng Tan,
Min Liu,
Fritz Lai,
Shi Min Heng,
Yong Fan,
Kenneth Tou En Chang,
Cheng-I Wang,
Jerry Kok Yen Chan,
Jianzhu Chen,
Qingfeng Chen
Frontiers in Immunology
11 Sep 2020
BMRC
Institute of Molecular and Cell Biology
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Zhisheng Her,
Joel Heng Loong Tan,
Yee-Siang Lim,
Sue Yee Tan,
Xue Ying Chan,
Wilson Wei Sheng Tan,
Min Liu,
Kylie Su Mei Yong,
Fritz Lai,
Erica Ceccarello,
Zhiqiang Zheng,
Yong Fan,
Kenneth Tou En Chang,
Lei Sun,
Shih Chieh Chang,
Chih-Liang Chin,
Guan Huei Lee,
Yock Young Dan,
Yun-Shen Chan,
Seng Gee Lim,
Jerry Kok Yen Chan,
K. George Chandy,
Qingfeng Chen
Frontiers in Immunology
13 Mar 2020
BMRC
Institute of Molecular and Cell Biology
Organoid cultures of MELAS neural cells reveal hyperactive Notch signaling that impacts neurodevelopment
- Winanto,
Zi Jian Khong,
Yong Fan,
Boon Seng Soh,
Shi-Yan Ng
Cell Death and Disease
10 Jan 2020
BMRC
Institute of Molecular and Cell Biology
A Humanized Mouse Model to Study Mast Cells Mediated Cutaneous Adverse Drug Reactions
Andrea Mencarelli,
Merry Gunawan,
Kylie Su Mei Yong,
Pradeep Bist,
Wilson Wei Sheng Tan,
Sue Yee Tan,
Min Liu,
Edwin Kunxiang Huang,
Yong Fan,
Jerry Kok Yen Chan,
Hae Woong Choi,
Soman N. Abraham,
Qingfeng Chen
Journal of Leukocyte Biology
7 Jan 2020
BMRC
Institute of Molecular and Cell Biology
Replacing what’s lost: a new era of stem cell therapy for Parkinson’s disease
Yong Fan,
Winanto,
Shi-Yan Ng
Translational Neurodegeneration
17 Jan 2019
BMRC
Institute of Molecular and Cell Biology
Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Sue Yee Tan,
Yong Wah Tan,
Xue Ying Chan,
Yong Fan,
Edwin Kunxiang Huang,
Yanyan Ke,
Wai Nam Liu,
Zhisheng Her,
Min Liu,
Huiyi Chen,
Kenneth Tou En Chang,
Jerry Kok Yen Chan,
Justin Jang Hann Chu,
Qingfeng Chen
Journal of Virology
17 Jan 2019
BMRC
Institute of Molecular and Cell Biology
Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Qingfeng Chen,
Yanyan Ke,
Wai Nam Liu,
Zhisheng Her,
Min Liu,
Sue Yee Tan,
Yong Wah Tan,
Xue Ying Chan,
Yong Fan,
Edwin Kunxiang Huang,
Huiyi Chen,
Kenneth Tou En Chang,
Jerry Kok Yen Chan,
Justin Jang Hann Chu
Journal of Virology
7 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes
Nicole Min Qian Pek,
Jin Hui Hor,
Shi-Yan Ng,
Yong Fan,
Beatrice Xuan Ho,
Jeremy Kah Sheng Pang,
Boon-Seng Soh
Stem Cell Research & Therapy
14 Nov 2018
BMRC
Institute of Molecular and Cell Biology
Human germline editing: Insights to future clinical treatment of diseases
Yanni Li,
Xiang Jin Kang,
Jeremy Kah Sheng Pang,
Boon Seng Soh,
Yang Yu,
Yong Fan
Protein & Cell
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