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18 Apr 2020
BMRC
Bioinformatics Institute
Sagacity in antibody humanization for therapeutics, diagnostics and research purposes: considerations of antibody elements and their roles
Wei-Li Ling,
Wai-Heng Lua,
Samuel Ken-En Gan
Antibody Therapeutics
1 Nov 2019
BMRC
Bioinformatics Institute
The quantification of antibody elements and receptors subunit expression using qPCR: The design of VH, VL, CH, CL, FcR subunits primers for a more holistic view of the immune system
Wei-Li Ling,
Yuen-Ling Ng,
Anil Wipat,
David Philip Lane,
Samuel Ken-En Gan
Journal of Immunological Methods
14 Apr 2019
BMRC
Bioinformatics Institute
Role of the IgE variable heavy chain in FcεRIα and superantigen binding in allergy and immunotherapy
Wai-Heng Lua,
Chinh Tran-To Su,
Joshua Yi Yeo,
Jun-Jie Poh,
Wei-Li Ling,
Ser-Xian Phu,
Samuel Ken-En Gan
Journal of Allergy and Clinical Immunology
12 Mar 2018
BMRC
Bioinformatics Institute
Effect of VH–VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding
Wei-Li Ling,
Wai-Heng Lua,
Jun-Jie Poh,
Joshua Yi Yeo,
David Philip Lane,
Samuel Ken-En Gan
Frontiers in Immunology
15 Jan 2018
BMRC
Bioinformatics Institute
The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding
Wai-Heng Lua,
Wei-Li Ling,
Joshua Yi Yeo,
Jun-Jie Poh,
David Philip Lane,
Samuel Ken-En Gan
Scientific Reports
8 Feb 2017
BMRC
Bioinformatics Institute
Discovery of a novel splice variant of Fcar (CD89) unravels sequence segments necessary for efficient secretion: A story of bad signal peptides and good ones that nevertheless do not make it
Wai-Heng Lua,
Wei-Li Ling,
Chinh Tran-To Su,
Joshua Yi Yeo,
Chandra S. Verma,
Birgit Eisenhaber,
Frank Eisenhaber,
Samuel Ken-En Gan
Cell Cycle
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