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Publication date Communities Collections Article title Author(s) Journal/Conference
24 Apr 2018 Others Experimental Drug Development Centre Fragment-based drug discovery of potent Protein Kinase C-iota inhibitors Jacek Kwiatkowski, Boping Liu, Doris Hui Ying Tee, Guoying Chen, Nur Huda Binte Ahmad, Yun Xuan Wong, Zhi Ying Poh, Shi Hua Ang, Eldwin Sum Wai Tan, Esther Ong, Nurul Dinie, Anders Poulsen, Vishal Pendharkar, Kanda Sangthongpitag, May Ann Lee, Sugunavathi D/O Sepramaniam, Soo Yei Ho, Joseph Cherian, Jeffrey Hill, Thomas Hugo Keller, Alvin Wei Hung Journal of Medicinal Chemistry
14 Aug 2017 Others Experimental Drug Development Centre Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor Thomas Hugo Keller, CongBao Kang, Yan Li, Hui Qi Ng, Anna Ngo, Joma Joy, Jeffrey Hill, Pearlyn Kwek, Alvin Hung Biomolecular NMR Assignments
20 Jul 2017 Others Experimental Drug Development Centre Structural characterization of the linked NS2B-NS3 protease of Zika virus Wint Wint Phoo, Weiling Wang, Ying Ru Loh, Zhenzhen Zhang, Elizabeth Yihui Ng, Thomas Hugo Keller, Dahai Luo, CongBao Kang, Yan Li FEBS Letters
6 Jul 2017 Others Experimental Drug Development Centre Structural dynamics of Zika virus NS2B-NS3 protease binding to dipeptide inhibitors Ying Ru Loh, Weiling Wang, Alvin Wei Hung, Thomas Hugo Keller, Dahai Luo, CongBao Kang, Yan Li, Zhenzhen Zhang, Wint Wint Phoo, Shuang Liu, Ming Wei Chen Structure
17 Oct 2015 Others Experimental Drug Development Centre Characterization of the interaction between E. coli topoisomerase IV E subunit and an ATP competitive inhibitor. Thomas Hugo Keller, CongBao Kang, Yan Li, Ying Lei Wong, Fui Mee Ng, Boping Liu, Yun Xuan Wong, Zhi Ying Poh, Siew Wen Then, Michelle Lee, Hui Qi Ng, Alvin Hung, Joseph Cherian, Jeffrey Hill Biochemical and Biophysical Research Communications
10 Aug 2015 Others Experimental Drug Development Centre NMR structural characterization of the N-terminal active domain of the gyrase B subunit from Pseudomonas aeruginosa and its complex with an inhibitor. Yan Li, Yun Xuan Wong, Zhi Ying Poh, Ying Lei Wong, Michelle Yueqi Lee, Hui Qi Ng, Boping Liu, Alvin Hung, Joseph Cherian, Jeffrey Hill, Thomas Hugo Keller, CongBao Kang FEBS Letters
25 Jun 2015 Others Experimental Drug Development Centre Discovery and Optimization of a Porcupine Inhibitor Athisayamani Jeyaraj Duraiswamy, May Ann Lee, Babita Madan, Shi Hua Ang, Eldwin Sum Wai Tan, Wei Wen Vivien Cheong, Zhiyuan Ke, Vishal Pendharkar, Li Jun Ding, Yun Shan Chew, Vithya Manoharan, Kanda Sangthongpitag, Jenefer Alam, Anders Poulsen, Soo Yei Ho, David Virshup, Thomas Hugo Keller Journal of Medicinal Chemistry