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23 Nov 2022
BMRC
Institute of Molecular and Cell Biology
Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model
Wai Nam Liu,
Wing Yan So,
Sarah L. Harden,
Shin Yie Fong,
Melissa Xin Yu Wong,
Wilson Wei Sheng Tan,
Sue Yee Tan,
Jessica Kai Lin Ong,
Ravisankar Rajarethinam,
Min Liu,
Jia Ying Cheng,
Lisda Suteja,
Joe Poh Sheng Yeong,
N. Gopalakrishna Iyer,
Darren Wan-Teck Lim,
Qingfeng Chen
Science Advances
18 Mar 2021
BMRC
Institute of Molecular and Cell Biology
Analysis and validation of human targets and treatments using a hepatocellular carcinoma‐immune humanized mouse model
Yue Zhao,
Jiaxu Wang,
Wai Nam Liu,
Shin Yie Fong,
Timothy Wai Ho Shuen,
Min Liu,
Sarah Harden,
Sue Yee Tan,
Jia Ying Cheng,
Wilson Wei Sheng Tan,
Jerry Kok Yen Chan,
Cheng Ean Chee,
Guan Huei Lee,
Han Chong Toh,
Seng Gee Lim,
Yue Wan,
Qingfeng Chen
Hepatology
15 Oct 2020
BMRC
Institute of Molecular and Cell Biology
Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics
Kylie Su Mei Yong,
Zhisheng Her,
Sue Yee Tan,
Wilson Wei Sheng Tan,
Min Liu,
Fritz Lai,
Shi Min Heng,
Yong Fan,
Kenneth Tou En Chang,
Cheng-I Wang,
Jerry Kok Yen Chan,
Jianzhu Chen,
Qingfeng Chen
Frontiers in Immunology
11 Sep 2020
BMRC
Institute of Molecular and Cell Biology
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Zhisheng Her,
Joel Heng Loong Tan,
Yee-Siang Lim,
Sue Yee Tan,
Xue Ying Chan,
Wilson Wei Sheng Tan,
Min Liu,
Kylie Su Mei Yong,
Fritz Lai,
Erica Ceccarello,
Zhiqiang Zheng,
Yong Fan,
Kenneth Tou En Chang,
Lei Sun,
Shih Chieh Chang,
Chih-Liang Chin,
Guan Huei Lee,
Yock Young Dan,
Yun-Shen Chan,
Seng Gee Lim,
Jerry Kok Yen Chan,
K. George Chandy,
Qingfeng Chen
Frontiers in Immunology
22 Apr 2020
BMRC
Institute of Molecular and Cell Biology
Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy
Wilson Wei Sheng Tan,
Sue Yee Tan,
Wai Nam Liu,
Shin Yie Fong,
Min Liu,
Jia Ying Cheng,
Sherlly Lim,
Lisda Suteja,
Edwin Kunxiang Huang,
Jerry Kok Yen Chan,
Narayanan Gopalakrishna Iyer,
Joe Poh Sheng Yeong,
Darren Wan-Teck Lim,
Qingfeng Chen
Cancers
10 Jan 2020
BMRC
Institute of Molecular and Cell Biology
A Humanized Mouse Model to Study Mast Cells Mediated Cutaneous Adverse Drug Reactions
Andrea Mencarelli,
Merry Gunawan,
Kylie Su Mei Yong,
Pradeep Bist,
Wilson Wei Sheng Tan,
Sue Yee Tan,
Min Liu,
Edwin Kunxiang Huang,
Yong Fan,
Jerry Kok Yen Chan,
Hae Woong Choi,
Soman N. Abraham,
Qingfeng Chen
Journal of Leukocyte Biology
17 Jan 2019
BMRC
Institute of Molecular and Cell Biology
Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Qingfeng Chen,
Yanyan Ke,
Wai Nam Liu,
Zhisheng Her,
Min Liu,
Sue Yee Tan,
Yong Wah Tan,
Xue Ying Chan,
Yong Fan,
Edwin Kunxiang Huang,
Huiyi Chen,
Kenneth Tou En Chang,
Jerry Kok Yen Chan,
Justin Jang Hann Chu
Journal of Virology
17 Jan 2019
BMRC
Institute of Molecular and Cell Biology
Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Sue Yee Tan,
Yong Wah Tan,
Xue Ying Chan,
Yong Fan,
Edwin Kunxiang Huang,
Yanyan Ke,
Wai Nam Liu,
Zhisheng Her,
Min Liu,
Huiyi Chen,
Kenneth Tou En Chang,
Jerry Kok Yen Chan,
Justin Jang Hann Chu,
Qingfeng Chen
Journal of Virology
30 Mar 2018
BMRC
Institute of Molecular and Cell Biology
Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy
Seng Gee Lim,
Qingfeng Chen,
Yue Zhao,
Timothy Wai Ho Shuen,
Tan Boon Toh,
Xue Ying Chan,
Min Liu,
Sue Yee Tan,
Yong Fan,
Hechuan Yang,
Shridhar Ganpathi Lyer,
Glenn Kunnath Bonney,
Eva Loh,
Kenneth Tou En Chang,
Thiam Chye Tan,
Weiwei Zhai,
Jerry Kok Yen Chan,
Edward Kai-Hua Chow,
Cheng Ean Chee,
Guan Huei Lee,
Yock Young Dan,
Pierce Kah-Hoe Chow,
Han Chong Toh
Gut
16 Mar 2018
BMRC
Institute of Molecular and Cell Biology
Bat-mouse bone marrow chimera: a novel animal model for dissecting the uniqueness of the bat immune system
Kylie Su Mei Yong,
Justin Han Jia Ng,
Zhisheng Her,
Ying Ying Hey,
Sue Yee Tan,
Wilson Wei Sheng Tan,
Sergio Erdal Irac,
Min Liu,
Xue Ying Chan,
Merry Gunawan,
Randy Jee Hiang Foo,
Dolyce Hong Wen Low,
Ian Hewitt Mendenhall,
Yok Teng Chionh,
Charles-Antoine Dutertre,
Qingfeng Chen,
Lin-Fa Wang
Scientific Reports
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