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29 Jan 2021
BMRC
Institute of Molecular and Cell Biology
H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Yichao Cai,
Ying Zhang,
Yan Ping Loh,
Jia Qi Tng,
Mei Chee Lim,
Zhendong Cao,
Anandhkumar Raju,
Erez Lieberman Aiden,
Shang Li,
Lakshmanan Manikandan,
Vinay Tergaonkar,
Greg Tucker-Kellogg,
Melissa Jane Fullwood
Nature Communications
8 Jan 2018
BMRC
Institute of Molecular and Cell Biology
HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
TingDong Yan,
Wen Fong Ooi,
Aditi Qamra,
Alice Cheung,
DongLiang Ma,
Gopinath Meenakshi Sundaram,
Chang Xu,
Manjie Xing,
LaiFong Poon,
Jing Wang,
Yan Ping Loh,
Jess Hui Jie Ho,
Joscelyn Jun Quan Ng,
Muhammad Khairul Ramlee,
Luay Aswad,
Steve G. Rozen,
Sujoy Ghosh,
Frederic A. Bard,
Prabha Sampath,
Vinay Tergaonkar,
James O.J. Davies,
Jim R. Hughes,
Eyleen Goh,
Xuezhi Bi,
Melissa Jane Fullwood,
Patrick Tan,
Shang Li
Nature Communications
12 Sep 2017
BMRC
Institute of Molecular and Cell Biology
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
Xiaosai Yao,
Jing Tan,
Kevin Junliang Lim,
Joanna Koh,
Wen Fong Ooi,
Zhimei Li,
Dachuan Huang,
Manjie Xing,
Yang Sun Chan,
James Zhengzhong Qu,
Su Ting Tay,
Giovani Wijaya,
Yue Ning Lam,
Jing Han Hong,
Ai Ping Lee-Lim,
Peiyong Guan,
Michelle Shu Wen Ng,
Cassandra Zhengxuan He,
Joyce Suling Lin,
Tannistha Nandi,
Aditi Qamra,
Chang Xu,
Swe Swe Myint,
James O. J. Davies,
Jian Yuan Goh,
Gary Loh,
Bryan C. Tan,
Steven G. Rozen,
Qiang Yu,
Iain Bee Huat Tan,
Christopher Wai Sam Cheng,
Shang Li,
Kenneth Tou En Chang,
Puay Hoon Tan,
David Lawrence Silver,
Alexander Lezhava,
Gertrud Steger,
Jim R. Hughes,
Bin Tean Teh,
Patrick Tan
Cancer Discovery
20 Apr 2015
BMRC
Institute of Molecular and Cell Biology
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity
Cheryl M. Koh,
Ekta Khattar,
Shi Chi Leow,
Chia Yi Liu,
Julius Müller,
Wei Xia Ang,
Yinghui Li,
Guido Franzoso,
Shang Li,
Ernesto Guccione,
Vinay Tergaonkar
Journal of Clinical Investigation
5 Mar 2015
BMRC
Institute of Molecular and Cell Biology
Quantitative assessment of telomerase components in cancer cell lines
Masahito Ikawa,
Shang Li,
Vinay Tergaonkar,
Semih Can Akıncılar,
Kee Chung Low,
Chia Yi Liu,
Ting Dong Yan,
Asami Oji
FEBS Letters
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