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Publication date Communities Collections Article title Author(s) Journal/Conference
31 Dec 2024 BMRC Bioprocessing Technology Institute Quality by Design in continuous bioprocessing: Investigating the impact of critical process parameters of multi-column chromatography during steady-state and transient phases Zi Ying Zheng, Ashley GuanBang Chen, Nuruljannah Dzulkiflie, Lyn Chiin Sim, Wen Qin Tang, Jiayu Leong, Wei Xuan Ler, Dawn Leong, Jake Chng, Norhaizat Bin Abdul Manan, Ian Walsh, Say Kong Ng, Maarten Pennings, Wei Zhang Journal of Chromatography A
11 Jul 2024 BMRC Bioprocessing Technology Institute Biomass specific perfusion rate as a control lever for the continuous manufacturing of biosimilar monoclonal antibodies from CHO cell cultures Jiayu Leong, Wen Qin Tang, Jake Chng, Wei Xuan Ler, Norhaizat Abdul Manan, Lyn Chiin Sim, Zi Ying Zheng, Wei Zhang, Ian Walsh, Gerben Zijlstra, Maarten Pennings, Say Kong Ng Biotechnology Journal
9 Jun 2024 BMRC Bioprocessing Technology Institute Temporal insights into molecular and cellular responses during rAAV production in HEK293T cells Alok Tanala Patra, Evan Tan, Yee Jiun Kok, Say Kong Ng, Xuezhi Bi Molecular Therapy - Methods & Clinical Development
9 Nov 2020 BMRC Bioprocessing Technology Institute Utility of Ion-Mobility Spectrometry for Deducing Branching of Multiply Charged Glycans and Glycopeptides in a High-Throughput Positive ion LC-FLR-IMS-MS Workflow Edward G. Pallister, Matthew S. F. Choo, Ian Walsh, Jien Nee Tai, Shi Jie Tay, Yuan Sheng Yang, Say Kong Ng, Pauline M. Rudd, Sabine L. Flitsch, Terry Nguyen-Khuong Analytical Chemistry
14 Nov 2019 BMRC Bioprocessing Technology Institute A human expression system based on HEK293 for the stable production of recombinant erythropoietin Christine Lin Chin, Justin Bryan Goh, Harini Srinivasan, Kaiwen Ivy Liu, Ali Gowher, Raghuvaran Shanmugam, Hsueh Lee Lim, Matthew Choo, Wen Qin Tang, Andy Hee-Meng Tan, Terry Nguyen-Khuong, Meng How Tan, Say Kong Ng Scientific Reports
6 Mar 2018 BMRC Bioprocessing Technology Institute Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclonal antibody Dawn Sow Zong Leong, Brian Kah Hui Teo, Janice Gek Ling Tan, Hayati Kamari, Yuan Sheng Yang, Peiqing Zhang, Say Kong Ng Scientific Reports
20 Dec 2017 BMRC Bioprocessing Technology Institute Impact of host cell line choice on glycan profile Say Kong Ng, Justin Bryan Goh Critical Reviews in Biotechnology
23 Mar 2016 BMRC Bioprocessing Technology Institute Characterization of a Polyethylene Glycol-Amphotericin B Conjugate Loaded with Free AMB for Improved Antifungal Efficacy Tessa Rui Min Tan, Kong Meng Hoi, Peiqing Zhang, Say Kong Ng PLoS One
2 Jun 2015 BMRC Bioprocessing Technology Institute Engineering selection stringency on expression vector for the production of recombinant human alpha-1-antitrypsin using Chinese Hamster Ovary Cells Christine Lin Chin, Hing Kah Chin, Cara Sze Hui Chin, Ethan Tingfeng Lai, Say Kong Ng BMC Biotechnology
4 Mar 2015 BMRC Bioprocessing Technology Institute Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed‐batch bioreactors Janice G. L. Tan, Yih Yean Lee, Tianhua Wang, Miranda G. S. Yap, Tin Wee Tan, Say Kong Ng Biotechnology Journal