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11 Jul 2024
BMRC
Bioprocessing Technology Institute
Biomass specific perfusion rate as a control lever for the continuous manufacturing of biosimilar monoclonal antibodies from CHO cell cultures
Jiayu Leong,
Wen Qin Tang,
Jake Chng,
Wei Xuan Ler,
Norhaizat Abdul Manan,
Lyn Chiin Sim,
Zi Ying Zheng,
Wei Zhang,
Ian Walsh,
Gerben Zijlstra,
Maarten Pennings,
Say Kong Ng
Biotechnology Journal
9 Jun 2024
BMRC
Bioprocessing Technology Institute
Temporal insights into molecular and cellular responses during rAAV production in HEK293T cells
Alok Tanala Patra,
Evan Tan,
Yee Jiun Kok,
Say Kong Ng,
Xuezhi Bi
Molecular Therapy - Methods & Clinical Development
9 Nov 2020
BMRC
Bioprocessing Technology Institute
Utility of Ion-Mobility Spectrometry for Deducing Branching of Multiply Charged Glycans and Glycopeptides in a High-Throughput Positive ion LC-FLR-IMS-MS Workflow
Edward G. Pallister,
Matthew S. F. Choo,
Ian Walsh,
Jien Nee Tai,
Shi Jie Tay,
Yuan Sheng Yang,
Say Kong Ng,
Pauline M. Rudd,
Sabine L. Flitsch,
Terry Nguyen-Khuong
Analytical Chemistry
14 Nov 2019
BMRC
Bioprocessing Technology Institute
A human expression system based on HEK293 for the stable production of recombinant erythropoietin
Christine Lin Chin,
Justin Bryan Goh,
Harini Srinivasan,
Kaiwen Ivy Liu,
Ali Gowher,
Raghuvaran Shanmugam,
Hsueh Lee Lim,
Matthew Choo,
Wen Qin Tang,
Andy Hee-Meng Tan,
Terry Nguyen-Khuong,
Meng How Tan,
Say Kong Ng
Scientific Reports
6 Mar 2018
BMRC
Bioprocessing Technology Institute
Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclonal antibody
Dawn Sow Zong Leong,
Brian Kah Hui Teo,
Janice Gek Ling Tan,
Hayati Kamari,
Yuan Sheng Yang,
Peiqing Zhang,
Say Kong Ng
Scientific Reports
20 Dec 2017
BMRC
Bioprocessing Technology Institute
Impact of host cell line choice on glycan profile
Say Kong Ng,
Justin Bryan Goh
Critical Reviews in Biotechnology
23 Mar 2016
BMRC
Bioprocessing Technology Institute
Characterization of a Polyethylene Glycol-Amphotericin B Conjugate Loaded with Free AMB for Improved Antifungal Efficacy
Tessa Rui Min Tan,
Kong Meng Hoi,
Peiqing Zhang,
Say Kong Ng
PLoS One
2 Jun 2015
BMRC
Bioprocessing Technology Institute
Engineering selection stringency on expression vector for the production of recombinant human alpha-1-antitrypsin using Chinese Hamster Ovary Cells
Christine Lin Chin,
Hing Kah Chin,
Cara Sze Hui Chin,
Ethan Tingfeng Lai,
Say Kong Ng
BMC Biotechnology
4 Mar 2015
BMRC
Bioprocessing Technology Institute
Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed‐batch bioreactors
Janice G. L. Tan,
Yih Yean Lee,
Tianhua Wang,
Miranda G. S. Yap,
Tin Wee Tan,
Say Kong Ng
Biotechnology Journal
11 Aug 2011
BMRC
Bioprocessing Technology Institute
Serum-free microcarrier based production of replication deficient Influenza vaccine candidate virus lacking NS1 using Vero cells
Allen Chen,
Swan Li Poh,
Christian Dietzsch,
Elisabeth Roethl,
Mylene L Yan,
Say Kong Ng
BMC Biotechnology
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