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31 Aug 2023
BMRC
Institute of Molecular and Cell Biology
Unveiling the Influence of Tumor Microenvironment and Spatial Heterogeneity on Temozolomide Resistance in Glioblastoma Using an Advanced Human In Vitro Model of the Blood‐Brain Barrier and Glioblastoma
Maxine SY Lam,
Joey JY Aw,
Damien Tan,
Ragavi Vijayakumar,
Hui Yi Grace Lim,
Swathi Yada,
Qing You Pang,
Nick Barker,
Carol Tang,
Beng Ti Ang,
Radoslaw M. Sobota,
Andrea Pavesi
Small
2 Feb 2023
BMRC
Institute of Molecular and Cell Biology
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma
Maxine S. Y. Lam,
Jose Antonio Reales-Calderon,
Jin Rong Ow,
Joey J. Y. Aw,
Damien Tan,
Ragavi Vijayakumar,
Erica Ceccarello,
Tommaso Tabaglio,
Yan Ting Lim,
Wang Loo Chien,
Fritz Lai,
Anthony Tan Tanoto,
Qingfeng Chen,
Radoslaw M. Sobota,
Giulia Adriani,
Antonio Bertoletti,
Ernesto Guccione,
Andrea Pavesi
Nature Communications
11 Mar 2020
BMRC
Institute of Molecular and Cell Biology
Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly
Shan Zhang,
Boris Reljić,
Chao Liang,
Baptiste Kerouanton,
Joel Celio Francisco,
Jih Hou Peh,
Camille Mary,
Narendra Suhas Jagannathan,
Volodimir Olexiouk,
Claire Tang,
Gio Fidelito,
Srikanth Nama,
Ruey-Kuang Cheng,
Caroline Lei Wee,
Loo Chien Wang,
Paula Duek Roggli,
Prabha Sampath,
Lydie Lane,
Enrico Petretto,
Radoslaw M. Sobota,
Suresh Jesuthasan,
Lisa Tucker-Kellogg,
Bruno Reversade,
Gerben Menschaert,
Lei Sun,
David A. Stroud,
Lena Ho
Nature Communications
14 Mar 2019
BMRC
Institute of Molecular and Cell Biology
Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA
Wendi Sun,
Lingyun Dai,
Han Yu,
Brenda Puspita,
Tianyun Zhao,
Feng Li,
Justin L. Tan,
Yan Ting Lim,
Ming Wei Chen,
Radoslaw M. Sobota,
Daniel G. Tenen,
Nayana Prabhu,
Pär Nordlund
Redox Biology
26 Feb 2019
BMRC
Institute of Molecular and Cell Biology
Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
Jolene Ooi,
Sarah R. Langley,
Xiaohong Xu,
Kagistia H. Utami,
Bernice Sim,
Yihui Huang,
Nathan P. Harmston,
Yi Lin Tay,
Amin Ziaei,
Ruizhu Zeng,
Donovan Low,
Folefac Aminkeng,
Radoslaw M. Sobota,
Florent Ginhoux,
Enrico Petretto,
Mahmoud A. Pouladi
Cell Reports
5 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
Franklin L. Zhong,
Kim Robinson,
Daniel Eng Thiam Teo,
Kiat-Yi Tan,
Chrissie Lim,
Cassandra R. Harapas,
Chien-Hsiung Yu,
William H. Xie,
Radoslaw M. Sobota,
Veonice Bijin Au,
Richard Hopkins,
Andrea D'Osualdo,
John C. Reed,
John E. Connolly,
Seth L. Masters,
Bruno Reversade
Journal of Biological Chemistry
15 Nov 2018
BMRC
Skin Research Institute of Singapore
2C-BioID: An Advanced Two Component BioID System for Precision Mapping of Protein Interactomes.
Alexandre Chojnowski,
Radoslaw M. Sobota,
Peh Fern Ong,
Wei Xie,
Xianrong Wong,
Oliver Dreesen,
Brian Burke,
Colin L. Stewart
iScience
26 Apr 2018
BMRC
Institute of Molecular and Cell Biology
Modulation of Protein-Interaction States through the Cell Cycle
Lingyun Dai,
Tianyun Zhao,
Xavier Bisteau,
Wendi Sun,
Nayana Prabhu,
Yan Ting Lim,
Radoslaw M. Sobota,
Philipp Kaldis,
Pär Nordlund
Cell
9 Mar 2018
BMRC
Institute of Molecular and Cell Biology
Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells
Chris Soon Heng Tan,
Ka Diam Go,
Xavier Bisteau,
Lingyun Dai,
Chern Han Yong,
Nayana Prabhu,
Mert Burak Ozturk,
Yan Ting Lim,
Lekshmy Sreekumar,
Johan Lengqvist,
Vinay Tergaonkar,
Philipp Kaldis,
Radoslaw M. Sobota,
Pär Nordlund
Science
8 Sep 2016
BMRC
p53 Laboratory
Going native: Complete removal of protein purification affinity tags by simple modification of existing tags and proteases
Hui Chin Goh,
Radoslaw M. Sobota,
Farid J. Ghadessy,
Saurabh Nirantar
Protein Expression and Purification
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