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16 Aug 2016
BMRC
Translational Laboratory in Genetic Medicine
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
Marta Garcia-Miralles,
Xin Hong,
Liang Juin Tan,
Nicholas S. Caron,
Yihui Huang,
Xuan Vinh To,
Rachel Yanping Lin,
Sonia Franciosi,
Spyros Papapetropoulos,
Liat Hayardeny,
Michael R. Hayden,
Kai-Hsiang Chuang,
Mahmoud A. Pouladi
Scientific Reports
26 Jan 2016
BMRC
Translational Laboratory in Genetic Medicine
Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease
Marta Garcia-Miralles,
Jolene Ooi,
Costanza Ferrari Bardile,
Liang Juin Tan,
Maya George,
Chester L. Drum,
Rachel Yanping Lin,
Michael R. Hayden,
Mahmoud A. Pouladi
Experimental Neurology
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