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25 Apr 2021 BMRC Institute of Molecular and Cell Biology Functional Comparison of Interferon‐α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon‐α and Interferon‐γ Signaling Jieliang Chen, Yaming Li, Fritz Lai, Yang Wang, Kathrin Sutter, Ulf Dittmer, Jianyu Ye, Wenjing Zai, Min Liu, Fang Shen, Min Wu, Kongying Hu, Baocun Li, Mengji Lu, Xiaonan Zhang, Jiming Zhang, Jianhua Li, Qingfeng Chen, Zhenghong Yuan
25 Mar 2021 BMRC Institute of Molecular and Cell Biology Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells Erica Ceccarello, Tommaso Tabaglio, Sarene Koh, Vincent Oei, Winnie Teo, Owen Julianto Jonathan, Andrea Pavesi, Qingfeng Chen, Antonio Bertoletti, Keng Boon Wee, Ernesto Guccione
18 Mar 2021 BMRC Institute of Molecular and Cell Biology Analysis and validation of human targets and treatments using a hepatocellular carcinoma‐immune humanized mouse model Yue Zhao, Jiaxu Wang, Wai Nam Liu, Shin Yie Fong, Timothy Wai Ho Shuen, Min Liu, Sarah Harden, Sue Yee Tan, Jia Ying Cheng, Wilson Wei Sheng Tan, Jerry Kok Yen Chan, Cheng Ean Chee, Guan Huei Lee, Han Chong Toh, Seng Gee Lim, Yue Wan, Qingfeng Chen
19 Feb 2021 BMRC Institute of Molecular and Cell Biology Establishment of Humanized Mice for the Study of HBV Fritz Lai, Cherry Yong Yi Wee, Qingfeng Chen
28 Jan 2021 BMRC Institute of Molecular and Cell Biology Exometabolomic Analysis of Decidualizing Human Endometrial Stromal and Perivascular Cells Sarah Louise Harden, Jieliang Zhou, Seley Gharanei, Maria Diniz-da-Costa, Emma S. Lucas, Liang Cui, Keisuke Murakami, Jinling Fang, Qingfeng Chen, Jan J. Brosens, Yie Hou Lee
15 Oct 2020 BMRC Institute of Molecular and Cell Biology Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics Kylie Su Mei Yong, Zhisheng Her, Sue Yee Tan, Wilson Wei Sheng Tan, Min Liu, Fritz Lai, Shi Min Heng, Yong Fan, Kenneth Tou En Chang, Cheng-I Wang, Jerry Kok Yen Chan, Jianzhu Chen, Qingfeng Chen
11 Sep 2020 BMRC Institute of Molecular and Cell Biology CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice Zhisheng Her, Joel Heng Loong Tan, Yee-Siang Lim, Sue Yee Tan, Xue Ying Chan, Wilson Wei Sheng Tan, Min Liu, Kylie Su Mei Yong, Fritz Lai, Erica Ceccarello, Zhiqiang Zheng, Yong Fan, Kenneth Tou En Chang, Lei Sun, Shih Chieh Chang, Chih-Liang Chin, Guan Huei Lee, Yock Young Dan, Yun-Shen Chan, Seng Gee Lim, Jerry Kok Yen Chan, K. George Chandy, Qingfeng Chen
22 Apr 2020 BMRC Institute of Molecular and Cell Biology Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy Wilson Wei Sheng Tan, Sue Yee Tan, Wai Nam Liu, Shin Yie Fong, Min Liu, Jia Ying Cheng, Sherlly Lim, Lisda Suteja, Edwin Kunxiang Huang, Jerry Kok Yen Chan, Narayanan Gopalakrishna Iyer, Joe Poh Sheng Yeong, Darren Wan-Teck Lim, Qingfeng Chen
10 Jan 2020 BMRC Institute of Molecular and Cell Biology A Humanized Mouse Model to Study Mast Cells Mediated Cutaneous Adverse Drug Reactions Andrea Mencarelli, Merry Gunawan, Kylie Su Mei Yong, Pradeep Bist, Wilson Wei Sheng Tan, Sue Yee Tan, Min Liu, Edwin Kunxiang Huang, Yong Fan, Jerry Kok Yen Chan, Hae Woong Choi, Soman N. Abraham, Qingfeng Chen
7 Jan 2020 BMRC Bioprocessing Technology Institute Preclinical Activity of Embryonic Annexin A2-Specific Chimeric Antigen Receptor T Cells Against Ovarian Cancer Leonard Leong, Heng Liang Tan, Simeon Cua, Kylie Su Mei Yong, Qingfeng Chen, Andre Choo
6 Dec 2019 BMRC Singapore Immunology Network Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy Alfonso Tan-Garcia, Fritz Lai, Joe Poh Sheng Yeong, Sergio E. Irac, Pei Y. Ng, Rasha Msallam, Jeffrey Chun Tatt Lim, Lu-En Wai, Christine Y. L. Tham, Su P. Choo, Tony Lim, Dan Y. Young, Roberta D’Ambrosio, Elisabetta Degasperi, Riccardo Perbellini, Evan Newell, Nina Le Bert, Florent Ginhoux, Antonio Bertoletti, Qingfeng Chen, Charles-Antoine Dutertre
17 Jun 2019 BMRC Institute of Molecular and Cell Biology Humanized Mouse Models for the Study of Hepatitis C and Host Interactions Kylie Su Mei Yong, Zhisheng Her, Qingfeng Chen
20 May 2019 BMRC Institute of Molecular and Cell Biology Cancer Immunotherapies and Humanized Mouse Drug Testing Platforms Qingfeng Chen, Jiaxu Wang, Wai Nam Liu, Yue Zhao
4 Mar 2019 BMRC Institute of Molecular and Cell Biology Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice Mandeep Kaur, Adam C. Drake, Guangan Hu, Stephen Rudnick, Qingfeng Chen, Ryan Phennicie, Ricardo Attar, Jeffrey Nemeth, Francois Gaudet, Jianzhu Chen
17 Jan 2019 BMRC Institute of Molecular and Cell Biology Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice Sue Yee Tan, Yong Wah Tan, Xue Ying Chan, Yong Fan, Edwin Kunxiang Huang, Yanyan Ke, Wai Nam Liu, Zhisheng Her, Min Liu, Huiyi Chen, Kenneth Tou En Chang, Jerry Kok Yen Chan, Justin Jang Hann Chu, Qingfeng Chen
17 Jan 2019 BMRC Institute of Molecular and Cell Biology Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice Qingfeng Chen, Yanyan Ke, Wai Nam Liu, Zhisheng Her, Min Liu, Sue Yee Tan, Yong Wah Tan, Xue Ying Chan, Yong Fan, Edwin Kunxiang Huang, Huiyi Chen, Kenneth Tou En Chang, Jerry Kok Yen Chan, Justin Jang Hann Chu
17 Nov 2018 BMRC Institute of Molecular and Cell Biology Humanized Mouse Models for the Study of Infection and Pathogenesis of Human Viruses Fritz Lai, Qingfeng Chen
6 Apr 2018 BMRC Singapore Institute for Clinical Sciences De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis Chunming Ding, Yen Ching Lim, Sook Yoong Chia, Arcinas Camille Esther Walet, Shaohai Xu, Kinyui Alice LO, Yanling Zhao, Dewen Zhu, Zhihui Shan, Qingfeng Chen, Melvin Khee-Shing Leow, Dan Xu, Lei Sun
6 Apr 2018 BMRC Institute of Molecular and Cell Biology De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis Chunming Ding, Yen Ching Lim, Sook Yoong Chia, Dan Xu, Arcinas Camille Esther Walet, Shaohai Xu, Kinyui Alice LO, Yanling Zhao, Dewen Zhu, Zhihui Shan, Qingfeng Chen, Melvin Khee-Shing Leow, Lei Sun
30 Mar 2018 BMRC Institute of Molecular and Cell Biology Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy Seng Gee Lim, Qingfeng Chen, Yue Zhao, Timothy Wai Ho Shuen, Tan Boon Toh, Xue Ying Chan, Min Liu, Sue Yee Tan, Yong Fan, Hechuan Yang, Shridhar Ganpathi Lyer, Glenn Kunnath Bonney, Eva Loh, Kenneth Tou En Chang, Thiam Chye Tan, Weiwei Zhai, Jerry Kok Yen Chan, Edward Kai-Hua Chow, Cheng Ean Chee, Guan Huei Lee, Yock Young Dan, Pierce Kah-Hoe Chow, Han Chong Toh
16 Mar 2018 BMRC Institute of Molecular and Cell Biology Bat-mouse bone marrow chimera: a novel animal model for dissecting the uniqueness of the bat immune system Kylie Su Mei Yong, Justin Han Jia Ng, Zhisheng Her, Ying Ying Hey, Sue Yee Tan, Wilson Wei Sheng Tan, Sergio Erdal Irac, Min Liu, Xue Ying Chan, Merry Gunawan, Randy Jee Hiang Foo, Dolyce Hong Wen Low, Ian Hewitt Mendenhall, Yok Teng Chionh, Charles-Antoine Dutertre, Qingfeng Chen, Lin-Fa Wang
9 Jan 2018 BMRC Institute of Molecular and Cell Biology Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs Yi Yang, Han Wu, Xiangjin Kang, Yanhui Liang, Ting Lan, Tianjie Li, Tao Tan, Jiangyun Peng, Quanjun Zhang, Geng An, Yali Liu, Qian Yu, Zhenglai Ma, Ying Lian, Boon Seng Soh, Qingfeng Chen, Ping Liu, Yaoyong Chen, Xiaofang Sun, Rong Li, Xiumei Zhen, Yang Yu, Xiaoping Li, Yong Fan
30 Nov 2017 BMRC Institute of Molecular and Cell Biology A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice Merry Gunawan, Zhisheng Her, Min Liu, Sue Yee Tan, Xue Ying Chan, Wilson Wei Sheng Tan, Shubasree Dharmaraaja, Yong Fan, Chee Bing Ong, Eva Loh, Kenneth Tou En Chang, Thiam Chye Tan, Jerry Kok Yen Chan, Qingfeng Chen
6 Oct 2017 BMRC Institute of Molecular and Cell Biology An improved pre-clinical patient-derived liquid xenograft mouse model for acute myeloid leukemia Zhisheng Her, Kylie Su Mei Yong, Kathirvel Paramasivam, Wilson Wei Sheng Tan, Xue Ying Chan, Sue Yee Tan, Min Liu, Yong Fan, Yeh Ching Linn, Kam Man Hui, Uttam Surana, Qingfeng Chen
8 Sep 2017 BMRC Institute of Molecular and Cell Biology Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model Zhiqiang Zheng, Ching Wooen Sze, Choong Tat Keng, Muthafar Al-Haddawi, Min Liu, Sue Yee Tan, Hwee Ling Kwek, Zhisheng Her Her, Xue Ying Chan, Bhaskar Barnwal, Eva Loh, Kenneth Tou En Chang, Thiam Chye Tan, Yee-Joo Tan, Qingfeng Chen
28 Aug 2017 BMRC Institute of Molecular and Cell Biology The niche for hematopoietic stem cell expansion: a collaboration network Qingfeng Chen
12 Oct 2015 BMRC Institute of Molecular and Cell Biology Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human Weijian Ye, Wei Jian Tan, Qingfeng Chen, Kylie Su Mei Yong, Min Liu, Shu Qi Tan, Eva Loh, Kenneth TE Chang, Thiam Chye Tan, Peter R. Preiser, Jianzhu Chen
6 Jul 2015 BMRC Institute of Molecular and Cell Biology Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection Kenneth T E Chang, Kylie Su Mei Yong, Choong Tat Keng, Ching Wooen Sze, Dahai Zheng, Zhiqiang Zheng, Shu Qi Tan, Jessica Jie Ying Ong, Sue Yee Tan, Eva Loh, Megha Haridas Upadya, Chik Hong Kuick, Hak Hotta, Seng Gee Lim, Thiam Chye Tan, Wanjin Hong, Jianzhu Chen, Yee-Joo Tan, Qingfeng Chen
22 Jun 2015 BMRC Institute of Molecular and Cell Biology De Novo Generated Human Red Blood Cells in Humanized Mice Support Plasmodium falciparum Infection Anburaj Amaladoss, Qingfeng Chen, Min Liu, Sara K. Dummler, Ming Dao, Subra Suresh, Jianzhu Chen, Peter R. Preiser, Claudio Romero Farias Marinho
11 Jun 2015 BMRC Institute of Bioengineering and Nanotechnology Microstructured dextran hydrogels for burst-free sustained release of PEGylated protein drugs Yee Joo Tan, Qingfeng Chen, Motoichi Kurisawa, Ki Hyun Bae, Fan Lee, Keming Xu, Choong Tat Keng, Sue Yee Tan
1 Jul 2014 BMRC Institute of Molecular and Cell Biology Viral Small T Oncoproteins Transform Cells by Alleviating Hippo-Pathway-Mediated Inhibition of the YAP Proto-oncogene Hung Thanh Nguyen, Xin Hong, Sam Tan, Qingfeng Chen, Lifang Chan, Marc Fivaz, Stephen M. Cohen, P. Mathijs Voorhoeve
1 Jan 2014 BMRC Institute of Molecular and Cell Biology Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations Kyle M. Loh, Lay Teng Ang, Jingyao Zhang, Vibhor Kumar, Jasmin Ang, Jun Qiang Auyeong, Kian Leong Lee, Siew Hua Choo, Christina Y.Y. Lim, Massimo Nichane, Junru Tan, Monireh Soroush Noghabi, Lisa Azzola, Elizabeth S. Ng, Jens Durruthy-Durruthy, Vittorio Sebastiano, Lorenz Poellinger, Andrew G. Elefanty, Edouard G. Stanley, Qingfeng Chen, Shyam Prabhakar, Irving L. Weissman, Bing Lim