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30 Jan 2020 Others Other Institutions Use of biomaterials for sustained delivery of anti-VEGF to treat retinal diseases Ivan Seah, Xinxin Zhao, Qianyu Lin, Zengping Liu, Steven Zheng Zhe Su, Yew Sen Yuen, Walter Hunziker, Gopal Lingam, Xian Jun Loh, Xinyi Su
8 Apr 2019 BMRC Institute of Molecular and Cell Biology Retinal-detachment repair and vitreous-like-body reformation via a thermogelling polymer endotamponade Gopal Lingam, Xian Jun Loh, Xinyi Su, Zengping Liu, Sing Shy Liow, Siew Li Lai, Asfa Alli-Shaik, Graham E. Holder, Bhav Harshad Parikh, Subramanian Krishnakumar, Zibiao Li, Mein Jin Tan, Jayantha Gunaratne, Veluchamy Amutha Barathi, Walter Hunziker, Rajamani Lakshminarayanan, Clement Woon Teck Tan, Caroline K. Chee, Paul Zhao
29 Oct 2018 BMRC Institute of Molecular and Cell Biology Candida albicans gains azole resistance by altering sphingolipid composition Jiaxin Gao, Haitao Wang, Zeyao Li, Ada Hang-Heng Wong, Yi-Zheng Wang, Yahui Guo, Xin Lin, Guisheng Zeng, Haoping Liu, Yue Wang, Jianbin Wang
18 May 2018 BMRC Bioinformatics Institute Antimicrobial activity profiles of Amphiphilic Xanthone derivatives are a function of their molecular Oligomerization Jun-Jie Koh, Shuimu Lin, Yang Bai, Wendy Wan Ling Sin, Thet Tun Aung, Jianguo Li, Verma Chandra, Konstantin Pervushin, Roger W. Beuerman, Shouping Liu
24 Apr 2018 BMRC Experimental Drug Development Centre Fragment-based drug discovery of potent Protein Kinase C-iota inhibitors Jacek Kwiatkowski, Boping Liu, Doris Hui Ying Tee, Guoying Chen, Nur Huda Binte Ahmad, Yun Xuan Wong, Zhi Ying Poh, Shi Hua Ang, Eldwin Sum Wai Tan, Esther Ong, Nurul Dinie, Anders Poulsen, Vishal Pendharkar, Kanda Sangthongpitag, May Ann Lee, Sugunavathi D/O Sepramaniam, Soo Yei Ho, Joseph Cherian, Jeffrey Hill, Thomas Hugo Keller, Alvin Wei Hung
23 Apr 2018 BMRC Bioinformatics Institute Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia Haiyan Yang, Lohitha Rao Chennamaneni, Melvyn Wai Tuck Ho, Shi Hua Ang, Eldwin Sum Wai Tan, Duraiswamy Athisayamani Jeyaraj, Yoon Sheng Yeap, Boping Liu, Esther Hq Ong, Joma Kanikadu Joy, John Liang Kuan Wee, Perlyn Kwek, Priya Retna, Nurul Dinie, Thuy Thi Hanh Nguyen, Shi Jing Tai, Vithya Manoharan, Vishal Pendharkar, Choon Bing Low, Yun Shan Chew, Susmitha Vuddagiri, Kanda Sangthongpitag, Meng Ling Choong, May Ann Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Anders Poulsen, Sharon Lim, Charles Chuah, Tiong Sin Ong, Jeffrey Hill, Alex Matter, Kassoum Nacro
9 Jan 2018 BMRC Institute of Molecular and Cell Biology Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs Yi Yang, Han Wu, Xiangjin Kang, Yanhui Liang, Ting Lan, Tianjie Li, Tao Tan, Jiangyun Peng, Quanjun Zhang, Geng An, Yali Liu, Qian Yu, Zhenglai Ma, Ying Lian, Boon Seng Soh, Qingfeng Chen, Ping Liu, Yaoyong Chen, Xiaofang Sun, Rong Li, Xiumei Zhen, Yang Yu, Xiaoping Li, Yong Fan
14 Feb 2017 BMRC Bioinformatics Institute Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design Jianguo Li, Jun-Jie Koh, Shouping Liu, Rajamani Lakshminarayanan, Chandra S. Verma, Roger W. Beuerman
30 Jun 2016 BMRC Experimental Drug Development Centre Escherichia coli topoisomerase IV E subunit and an inhibitor binding mode revealed by NMR spectroscopy Yan Li, Ying Lei Wong, Fui Mee Ng, Boping Liu, Yun Xuan Wong, Zhin Ying Poh, Shuang Liu, Siew Wen Then, Michelle Yueqi Lee, Hui Qi Ng, Qiwei Huang, Alvin W Hung, Joseph Cherian, Jeffrey Hill, Thomas H Keller, CongBao Kang
13 May 2016 BMRC Bioinformatics Institute Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria Rajamani Lakshminarayanan, Wei Xiang Tan, Thet Tun Aung, Eunice Tze Leng Goh, Nandhakumar Muruganantham, Jianguo Li, Jamie Ya Ting Chang, Neha Dikshit, Padmanabhan Saraswathi, Rayne Rui Lim, Tse Siang Kang, Vanniarajan Balamuralidhar, Bindu Sukumaran, Chandra S. Verma, Jayaraman Sivaraman, Shyam Sunder Chaurasia, Shouping Liu, Roger W. Beuerman
24 Mar 2016 BMRC Experimental Drug Development Centre Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 & 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells Kassoum Nacro, Zhi Ying Poh, Samantha Guo, Joseph Cherian, Duraiswamy Jeyaraj, Yun Xuan Wong, Melvyn Ho, Hai Yan Yang, Joma Kanikadu Joy, Zekui Perlyn Kwek, Boping Liu, John Laing Kuan Wee Wee, Esther Hq Ong, Meng Ling Choong, Anders Poulsen, May Ann Lee, Vishal Pendharkar, Vithya Manoharan, Yun Shan Chew, Kanda Sangthongpitag, Sharon Lim, S. Tiong Ong, Jeffrey Hill, Thomas H. Keller
4 Nov 2015 BMRC Experimental Drug Development Centre Biophysical studies of type II topoisomerases from Pseudomonas aeruginosa and Streptococcus pneumoniae substantiate their binding modes to a bis-pyridylurea inhibitor. Boping Liu, CongBao Kang, Yan Li, Joseph Cherian, Hui Qi Ng, Michelle Yueqi Lee, Nur Huda Ahmad, Zhi Ying Poh, Yun Xuan Wong, Qiwei Huang, Ying Lei Wong, Alvin Hung, Jeffrey Hill, Thomas Keller
17 Oct 2015 BMRC Experimental Drug Development Centre Characterization of the interaction between E. coli topoisomerase IV E subunit and an ATP competitive inhibitor. Thomas Hugo Keller, CongBao Kang, Yan Li, Ying Lei Wong, Fui Mee Ng, Boping Liu, Yun Xuan Wong, Zhi Ying Poh, Siew Wen Then, Michelle Lee, Hui Qi Ng, Alvin Hung, Joseph Cherian, Jeffrey Hill
10 Aug 2015 BMRC Experimental Drug Development Centre NMR structural characterization of the N-terminal active domain of the gyrase B subunit from Pseudomonas aeruginosa and its complex with an inhibitor. Yan Li, Yun Xuan Wong, Zhi Ying Poh, Ying Lei Wong, Michelle Yueqi Lee, Hui Qi Ng, Boping Liu, Alvin Hung, Joseph Cherian, Jeffrey Hill, Thomas Hugo Keller, CongBao Kang
10 Jan 2015 BMRC Bioinformatics Institute A novel fragment based strategy for membrane active antimicrobials against MRSA Jianguo Li, Shouping Liu, Jun-Jie Koh, Hanxun Zou, Rajamani Lakshminarayanan, Yang Bai, Konstantin Pervushin, Lei Zhou, Chandra Verma, Roger W. Beuerman
3 Feb 2014 BMRC Bioinformatics Institute Synthetic Multivalent Antifungal Peptides Effective against Fungi Charles Tang, Siti Radiah Binte Safie, Yih Lin Lim, Howard Riezman, Rajamani Lakshminarayanan, Shouping Liu, Jianguo Li, Muruganantham Nandhakumar, Thet Tun Aung, Eunice Goh, Jamie Ya Ting Chang, Padhmanaban Saraswathi, Zhou Lei, Roger Beuerman