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2 Apr 2019
BMRC
Singapore Bioimaging Consortium
A new hyperpolarized 13C ketone body probe reveals an increase in acetoacetate utilization in the diabetic rat heart
Desiree Abdurrachim,
Chern Chiuh Woo,
Xing Qi Teo,
Wei Xin Chan,
George K. Radda,
Philip Teck Hock Lee
Scientific Reports
11 Dec 2018
BMRC
Singapore Bioimaging Consortium
Cardiac metabolic modulation upon low-carbohydrate lowprotein ketogenic diet in diabetic rats studied in vivo using hyperpolarized 13C pyruvate, butyrate and acetoacetate probes
Desiree Abdurrachim,
Xing Qi Teo,
Chern Chiuh Woo,
Sing Yee Ong,
Nurul Farhana Salleh,
Janise Lalic,
Ru-San Tan,
Philip Teck Hock Lee
Diabetes, Obesity and Metabolism
17 Sep 2018
BMRC
Singapore Bioimaging Consortium
Empagliflozin reduces myocardial ketone utilization while preserving glucose utilization in diabetic hypertensive heart disease: A hyperpolarized 13C magnetic resonance spectroscopy study
Desiree Abdurrachim,
Xing Qi Teo,
Chern Chiuh Woo,
Wei Xin Chan,
Janise Lalic,
Carolyn S. P. Lam,
Philip Teck Hock Lee
Diabetes, Obesity and Metabolism
1 Jun 2018
BMRC
Singapore Bioimaging Consortium
Inhibiting Glycine Decarboxylase Suppresses Pyruvate-to-Lactate Metabolism in Lung Cancer Cells
Philip Teck Hock Lee,
Chern Chiuh Woo,
Kavita Kaur,
Wei Xin Chan,
Xing Qi Teo
Frontiers in Oncology
6 Jul 2016
BMRC
Singapore Bioimaging Consortium
Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma
Chern Chiuh Woo,
Way Cherng Chen,
Xing Qi Teo,
George K. Radda,
Philip Teck Hock Lee
Oncotarget
22 Aug 2012
BMRC
Singapore Bioimaging Consortium
In Vivo hyperpolarized carbon‐13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin‐resistant mouse model
Philip Teck Hock Lee,
Waifook Leong,
Trish Tan,
Miangkee Lim,
Weiping Han,
George K. Radda
Hepatology
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