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9 Aug 2019
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BMRC
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Institute of Molecular and Cell Biology
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A STAT3-based gene signature stratifies glioma patients for targeted therapy
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Melanie Si Yan Tan,
Edwin Sandanaraj,
Yuk Kien Chong,
See Wee Lim,
Lynnette Wei Hsien Koh,
Wai Hoe Ng,
Nguan Soon Tan,
Patrick Tan,
Beng Ti Ang,
Carol Tang
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Nature Communications
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20 Oct 2018
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BMRC
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Institute of Molecular and Cell Biology
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Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs
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Maegan Miang Kee Lim,
Jonathan Wei Kiat Wee,
Jen Chi Soong,
Damien Chua,
Wei Ren Tan,
Marco Lizwan,
Yinliang Li,
Ziqiang Teo,
Wilson Wen Bin Goh,
Pengcheng Zhu,
Nguan Soon Tan
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Molecular Cancer
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24 Jul 2018
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BMRC
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Singapore Immunology Network
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LYVE-1+ macrophages maintain arterial tone through hyaluronan-mediated regulation of smooth muscle cell collagen
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Hwee Ying Lim,
Sheau Yng Lim,
Chek Kun Tan,
Chung Hwee Thiam,
Chi Ching Goh,
Daniel Carbajo,
Samantha Hui Shang Chew,
Peter See,
Svetoslav Chakarov,
Xiao Nong Wang,
Li Hui Lim,
Louise A. Johnson,
Josephine Lum,
Chui Yee Fong,
Ariff Bongso,
Arijit Biswas,
Chern Goh,
Maximilien Evrard,
Kim Pin Yeo,
Ranu Basu,
Jun Kit Wang,
Yingrou Tan,
Rohit Jain,
Shweta Tikoo,
Cleo Choong,
Wolfgang Weninger,
Michael Poidinger,
Richard E. Stanley,
Matthew Collin,
Nguan Soon Tan,
Lai Guan Ng,
David G. Jackson,
Florent Ginhoux,
Ve´ronique Angeli
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Immunity
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27 Jun 2018
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BMRC
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Institute of Molecular and Cell Biology
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Insights into the Role of PPARβ/δ in NAFLD
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Jiapeng Chen,
Alexandra Montagner,
Nguan Soon Tan,
Walter Wahli
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International Journal of Molecular Sciences
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10 May 2018
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BMRC
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Institute of Molecular and Cell Biology
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An aPPARent Functional Consequence in Skeletal Muscle Physiology via Peroxisome Proliferator-Activated Receptors
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Wendy Wen Ting Phua,
Melissa Xin Yu Wong,
Zehuan Liao,
Nguan Soon Tan
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International Journal of Molecular Sciences
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3 Apr 2018
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BMRC
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Institute of Molecular and Cell Biology
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Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression
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Ming Keat Sng,
Jeremy Soon Kiat Chan,
Ziqiang Teo,
Terri Phua,
Eddie Han Pin Tan,
Jonathan Wei Kiat Wee,
Nikki Jun Ning Koh,
Chek Kun Tan,
Jia Peng Chen,
Mintu Pal,
Benny Meng Kiat Tong,
Ya Lin Tnay,
Xuan Rui Ng,
Pengcheng Zhu,
Shunsuke Chiba,
Xiaomeng Wang,
Walter Wahli,
Nguan Soon Tan
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Cell Discovery
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25 Jan 2018
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BMRC
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Institute of Molecular and Cell Biology
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ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response (Pending publish)
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Eddie Han Pin Tan,
Ming Keat Sng,
Ivan Shun Bo How,
Jeremy Soon Kiat Chan,
Jiapeng Chen,
Chek Kun Tan,
Walter Wahli,
Nguan Soon Tan
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24 Aug 2017
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BMRC
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Institute of Molecular and Cell Biology
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Sustained-releasing hollow microparticles with dual-anticancer drugs elicit greater shrinkage of tumor spheroids
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Jong-Suep Baek,
Chee Chong Choo,
Nguan Soon Tan,
Say Chye Joachim Loo
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Oncotarget
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19 Aug 2017
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BMRC
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Institute of Molecular and Cell Biology
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Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile
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Chee Wai Ku,
Zhen Wei Tan,
Mark Kit Lim,
Zhi Yang Tam,
Sean Pin Ng,
John Carson Allen,
Sze Min Lek,
Thiam Chye Tan,
Nguan Soon Tan
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4 Aug 2017
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BMRC
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Institute of Molecular and Cell Biology
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Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
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Pazhanichamy Kalailingam,
Hui Bing Tan,
Neeraj Jain,
Ming Keat Sng,
Jeremy Soon Kiat Chan,
Nguan Soon Tan,
Thirumaran Thanabalu
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15 Apr 2017
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BMRC
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Institute of Molecular and Cell Biology
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Feeding Angptl4−/− mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites (Pending publish)
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Antwi-Boasiako Oteng,
Asmita Bhattacharya,
Susanne Brodesser,
Ling Qi,
Nguan Soon Tan,
Sander Kersten
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13 Mar 2017
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BMRC
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Institute of Molecular and Cell Biology
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Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin
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Yinliang Li,
Terri Phua,
Ming Keat Sng,
Eddie Han Pin Tan,
Dickson Shao Liang Chee,
Jonathan Wei Kiat Wee,
Ziqiang Teo,
Jeremy Soon Kiat Chan,
Maegan Miang Kee Lim,
Chek Kun Tan,
Pengcheng Zhu,
Velmurugesan Arulampalam,
Nguan Soon Tan
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Scientific Reports
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6 Mar 2017
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BMRC
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Institute of Molecular and Cell Biology
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Validation of serum progesterone <35nmol/L as a predictor of miscarriage among women with threatened miscarriage
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Sze Min Lek,
Chee Wai Ku,
John C. Allen Jr,
Rahul Malhotra,
Nguan Soon Tan,
Truls Østbye,
Thiam Chye Tan
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BMC Pregnancy and Childbirth
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7 Oct 2015
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BMRC
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Institute of Molecular and Cell Biology
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A Periosteum-Inspired 3D Hydrogel-Bioceramic Composite for Enhanced Bone Regeneration (Pending publish)
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Peggy Puk Yik Chan,
Timothy Thatt Yang Tan,
Cleo Choong,
Yong Yao Chun,
Jun Kit Wang,
Nguan Soon Tan
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Macromolecular Bioscience
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1 Sep 2015
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BMRC
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Institute of Molecular and Cell Biology
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Delivery of doxorubicin and paclitaxel from double-layered microparticles: The effects of layer thickness and dual-drug vs. single-drug loading (Pending publish)
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Wei Li Lee,
Wei Mei Guo,
Vincent H.B. Ho,
Amitaksha Saha,
Han Chung Chong,
Nguan Soon Tan,
Ern Yu Tan,
Say Chye Joachim Loo
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Acta Biomaterialia
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20 Jul 2015
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BMRC
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Institute of Molecular and Cell Biology
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Targeting vascular leakage in lung inflammation
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Liang Li,
Vincent T.K. Chow,
Nguan Soon Tan
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Oncotarget
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10 Jul 2015
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BMRC
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Institute of Molecular and Cell Biology
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Bio-inspired micropatterned hydrogel to direct and deconstruct hierarchical processing of geometry-force signals by human mesenchymal stem cells during smooth muscle cell differentiation
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Chor Yong Tay,
Yun-Long Wu,
Pingqiang Cai,
Nguan Soon Tan,
Subbu S Venkatraman,
Xiaodong Chen,
Lay Poh Tan
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NPG Asia Materials
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15 Jun 2015
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BMRC
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Institute of Molecular and Cell Biology
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Highly selective anti-cancer properties of ester functionalized enantiopure dinuclear gold(I)-diphosphine (Pending publish)
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Bin-Bin Li,
Yu-Xiang Jia,
Peng-Cheng Zhu,
Renta Jonathan Chew,
Yongxin Li,
Nguan Soon Tan,
Pak-Hing Leung
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European Journal of Medicinal Chemistry
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2 Jun 2015
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BMRC
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Institute of Molecular and Cell Biology
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How can we better predict the risk of spontaneous miscarriage among women experiencing threatened miscarriage? (Pending publish)
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Chee Wai Ku,
John C. Allen,
Rahul Malhotra,
Han Chung Chong,
Nguan Soon Tan,
Truls Østbye,
Sze Min Lek,
Désirée Lie,
Thiam Chye Tan
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Gynecological Endocrinology
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22 Apr 2015
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BMRC
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Institute of Molecular and Cell Biology
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Polymer-Enriched 3D Graphene Foams for Biomedical Applications (Pending publish)
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Jun Kit Wang,
Gordon Minru Xiong,
Minmin Zhu,
Barbaros Özyilmaz,
Antonio Helio Castro Neto,
Nguan Soon Tan,
Cleo Choong
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ACS Applied Materials & Interfaces
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11 Mar 2015
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BMRC
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Institute of Molecular and Cell Biology
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Culturing Fibroblasts in 3D Human Hair Keratin Hydrogels (Pending publish)
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Shuai Wang,
Zhenxing Wang,
Selin Ee Min Foo,
Nguan Soon Tan,
Yuan Yuan,
Weisi Lin,
Zhiyong Zhang,
Kee Woei Ng
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ACS Applied Materials & Interfaces
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5 Feb 2015
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BMRC
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Institute of Molecular and Cell Biology
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Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia
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Liang Li,
Han Chung Chong,
Say Yong Ng,
Ka Wai Kwok,
Ziqiang Teo,
Eddie Han Pin Tan,
Chee Chong Choo,
Ju Ee Seet,
Hyung Won Choi,
Martin Lindsay Buist,
Vincent Tak Kwong Chow,
Nguan Soon Tan
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Cell Reports
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26 Nov 2014
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BMRC
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Institute of Molecular and Cell Biology
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From Flab to Fab: Transforming Surgical Waste into an Effective Bioactive Coating Material (Pending publish)
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Baiwen Luo,
Shaojun Yuan,
Selin Ee Min Foo,
Marcus Thien Chong Wong,
Thiam Chye Lim,
Nguan Soon Tan,
Cleo Choong
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Advanced Healthcare Materials
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7 Nov 2014
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BMRC
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Institute of Molecular and Cell Biology
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Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment (Pending publish)
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Xiaoling Wang,
Ming Keat Sng,
Selin Foo,
Han Chung Chong,
Wei Li Lee,
Mark Boon Yang Tang,
Kee Woei Ng,
Baiwen Luo,
Cleo Choong,
Marcus Thien Chong Wong,
Benny Meng Kiat Tong,
Shunsuke Chiba,
Say Chye Joachim Loo,
Pengcheng Zhu,
Nguan Soon Tan
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Journal of Controlled Release
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1 Jul 2014
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BMRC
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Institute of Molecular and Cell Biology
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Angiopoietin-like 4 Stimulates STAT3-mediated iNOS Expression and Enhances Angiogenesis to Accelerate Wound Healing in Diabetic Mice
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Jeremy Soon Kiat Chan,
Chi Qin Goh,
Natalia V Gounko,
Xiaoling Wang,
Han Chung Chong,
Selin Foo,
Marcus Thien Chong Wong,
Cleo Choong,
Sander Kersten,
Nguan Soon Tan,
Baiwen Luo
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Molecular Therapy
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22 Apr 2014
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BMRC
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Institute of Molecular and Cell Biology
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A 3D Biomimetic Model of Tissue Stiffness Interface for Cancer Drug Testing
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Chee Ren Ivan Lam,
Hui Kian Wong,
Spencer Nai,
Chee Kai Chua,
Nguan Soon Tan,
Lay Poh Tan
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Molecular Pharmaceutics
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3 Sep 2013
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BMRC
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Institute of Molecular and Cell Biology
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Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria
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Bow Ho,
Jeak Ling Ding,
Saswati Panda,
Jing Zhang,
Nguan Soon Tan
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The EMBO Journal
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