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1 Dec 2020 BMRC Singapore Institute for Clinical Sciences Association of Cord Blood Thyroid-Stimulating Hormone Levels with Maternal, Delivery and Infant Factors Karen Tan, Anne Chu, See Ling Loy, Victor Samuel Rajadurai, Clement Ho, Yap Seng Chong, Neerja Karnani, Yung Seng Lee, Kok Peng Fabian Yap, Shiao-Yng Chan
22 Apr 2020 BMRC Singapore Institute for Clinical Sciences Implication of gut microbiota in the association between infant antibiotic exposure and childhood obesity and adiposity accumulation Ling-Wei Chen, Jia Xu, Shu E Soh, Izzuddin M. Aris, Mya-Thway Tint, Peter D. Gluckman, Kok Hian Tan, Lynette Pei-chi Shek, Yap-Seng Chong, Fabian Yap, Keith M. Godfrey, Jack A. Gilbert, Neerja Karnani, Yung Seng Lee
20 Dec 2019 BMRC Singapore Institute for Clinical Sciences Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities Philip Titcombe, Eugenia Migliavacca, Stacey K. H. Tay, Harnish P. Patel, Tanja Sonntag, Gabriele Civiletto, Craig McFarlane, Terence Forrester, Sheila J. Barton, Melvin K. Leow, Elie Antoun, Aline Charpagne, Yap Seng Chong, Patrick Descombes, Lei Feng, Patrice Francis-Emmanuel, Emma S. Garratt, Maria Pilar Giner, Curtis O. Green, Sonia Karaz, Narasimhan Kothandaraman, Julien Marquis, Sylviane Metairon, Sofia Moco, Gail Nelson, Sherry Ngo, Tony Pleasants, Frederic Raymond, Avan A. Sayer, Chu Ming Sim, Jo Slater-Jefferies, Holly E. Syddall, Pei Fang Tan, Candida Vaz, Leo D. Westbury, Gerard Wong, Yonghui Wu, Cyrus Cooper, Allan Sheppard, Keith M. Godfrey, Karen A. Lillycrop, Neerja Karnani, Jerome N. Feige
20 Dec 2019 BMRC Singapore Institute for Clinical Sciences Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities Eugenia Migliavacca, Stacey K. H. Tay, Harnish P. Patel, Tanja Sonntag, Gabriele Civiletto, Craig McFarlane, Terrence Forrester, Shelia J. Barton, Melvin K. Leow, Elie Antoun, Aline Charpagne, Yap Seng Seng Chong, Patrick Descombes, Lei Feng, Patrice Francis-Emmanuel, Emma S. Garratt, Maria Pilar Giner, Curtis O. Green, Sonia Karaz, Narasimhan Kothandaraman, Julien Marquis, Sylviane Metairon, Sofia Moco, Gail Nelson, Sherry Ngo, Tony Pleasants, Frederic Raymond, Avan A. Sayer, Chu Ming Sim, Jo Slater-Jefferies, Holly E. Syddall, Pei Fang Tan, Philip Titcombe, Candida Vaz, Leo D. Westbury, Gerald Wong, Yonghui Wu, Cyrus Cooper, Allan Sheppard, Keith M. Godfrey, Karen .A. Lillycrop, Neerja Karnani, Jerome N. Feige
17 Oct 2019 BMRC Genome Institute of Singapore Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore Degang Wu, Jinzhuang Dou, Xiaoran Chai, Claire Bellis, Andreas Wilm, Chih Chuan Shih, Wendy Wei Jia Soon, Nicolas Bertin, Clarabelle Bitong Lin, Chiea Chuen Khor, Michael DeGiorgio, Shanshan Cheng, Li Bao, Neerja Karnani, William Ying Khee Hwang, Sonia Davila, Patrick Tan, Asim Shabbir, Angela Moh, Eng-King Tan, Jia Nee Foo, Luih Ling Goh, Khai Pang Leong, Roger S. Y. Foo, Carolyn Su Ping Lam, Arthur Mark Richards, Ching-Yu Cheng, Tin Aung, Tien Yin Wong, Huck Hui Ng, Jianjun Liu, Chaolong Wang
28 Aug 2019 BMRC Singapore Institute for Clinical Sciences Determinants of intramyocellular lipid accumulation in early childhood Navin Michael, Varsha Gupta, Suresh Anand Sadananthan, Aparna Sampathkumar, Li Chen, Hong Pan, Mya Thway Tint, Kuan Jin Lee, See Ling Loy, Izzuddin M. Aris, Lynette Pei-chi Shek, Fabian Kok Peng Yap, Keith M. Godfrey, Melvin K.-S. Leow, Yung Seng Lee, Michael S. Kramer, Christiani Jeyakumar Henry, Marielle Valerie Fortier, Yap Seng Seng Chong, Peter D. Gluckman, NNeerja Karnani, S. Sendhil Velan
17 May 2019 BMRC Singapore Institute for Clinical Sciences In-utero epigenetic factors are associated with early-onset myopia in young children Wei Jie Seow, Cheryl S. Ngo, Hong Pan, Veluchamy Amutha Barathi, Stuart W. Tompson, Kristina N. Whisenhunt, Eranga Vithana, Yap-Seng Chong, Suh-Hang H. Juo, Pirro Hysi, Terri L. Young, Neerja Karnani, Seang Mei. Saw
11 Feb 2019 BMRC Singapore Institute for Clinical Sciences Analysis of two birth tissues provides new insights into the epigenetic landscape of neonates born preterm Yonghui Wu, Xinyi Lin, Ives Yubin Lim, Li Chen, Ai Ling Teh, Julia L. MacIsaac, Kok Hian Tan, Michael S. Kobor, Yap Seng Chong, Peter D. Gluckman, Neerja Karnani
1 Feb 2019 BMRC Singapore Institute for Clinical Sciences Association Between Early Life Weight Gain and Abdominal Fat Partitioning at 4.5 Years is Sex, Ethnicity, and Age Dependent Suresh Anand Sadananthan, Mya Thway Tint, Navin Michael, Izzuddin M. Aris, See Ling Loy, Kuan Jin Lee, Lynette Pei-chi Shek, Fabian Kok Peng Yap, Kok Hian Tan, Keith M. Godfrey, Melvin Khee-Shing Leow, Yung Seng Lee, Michael S. Kramer, Peter D. Gluckman, Yap Seng Chong, Neerja Karnani, Christiani Jeyakumar Henry, Marielle Valerie Fortier, S. Sendhil Velan
11 Oct 2018 BMRC Singapore Institute for Clinical Sciences Cell type-specific DNA methylation in neonatal cord tissue and cord blood: a 850K-reference panel and comparison of cell types Xinyi Lin, Jane Yi Lin Tan, Ai Ling Teh, Ives Yubin Lim, Samantha J. Liew, Julia L. MacIsaac, Yap Seng Chong, Peter D. Gluckman, Michael S. Kobor, Clara Yujing Cheong, Neerja Karnani
6 Jun 2018 BMRC Singapore Institute for Clinical Sciences Long-chain polyunsaturated fatty acids, gestation duration, and birth size: a Mendelian randomization study using fatty acid desaturase variants Jonathan Y. Bernard, Hong Pan, Izzuddin M. Aris, Margarita Moreno-Betancur, Shu-E Soh, Fabian Yap, Kok Hian Tan, Lynette P. Shek, Yap-Seng Chong, Peter D. Gluckman, Philip C. Calder, Keith M. Godfrey, Mary Foong-Fong Chong, Michael .S Kramer, Neerja Karnani, Yung Seng Lee
10 Jan 2018 BMRC Singapore Institute for Clinical Sciences DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up Kieran J. O'Donnell, Li Chen, Julia L. MacIsaac, Lisa M. McEwen, Thao Nguyen, Katherine Beckmann, Yuecai Zhu, Lawrence Ming Chen, Jeanne Brooks-Gunn, David Goldman, Elena L. Grigorenko, James F. Leckman, Josie Diorio, Neerja Karnani, David L. Olds, Joanna D. Holbrook, Michael S. Kobor, Michael J. Meaney
5 Dec 2017 BMRC Singapore Institute for Clinical Sciences Choice of surrogate tissue influences neonatal EWAS findings Xinyi Lin, Ai Ling Teh, Li Chen, Ives Yubin Lim, Pei Fang Tan, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Yung Seng Lee, Joanna D. Holbrook, Keith M. Godfrey, Michael J. Meaney, Michael S. Kobor, Yap Seng Chong, Peter D. Gluckman, Neerja Karnani
22 Nov 2017 BMRC Singapore Institute for Clinical Sciences Positive Maternal Mental Health During Pregnancy Associated With Specific Forms of Adaptive Development in Early Childhood: Evidence from a Longitudinal Study Desiree Y. Phua, Michelle K. Z. L. Kee, Dawn X. P. Koh, Anne Rifkin-Graboi, Mary Daniel, Helen Chen, Yap Seng Chong, Birit F. P. Broekman, Iliana Magiati, Neerja Karnani, Michael Pluess, Michael J. Meaney
26 Apr 2017 BMRC Singapore Institute for Clinical Sciences ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity Karen Lillycrop, Robert Murray, Clara Cheong, Ai Ling Teh, Rebecca Clarke-Harris, Sheila Barton, Paula Costello, Emma Garratt, Eloise Cook, Philip Titcombe, Bhuvaneshwari Shunmuganathan, Carolina Paras Chavez, Philip C. Calder, Fabian Yap, Yung Seng Lee, Yap Seng Chong, Philip E. Melton, Lawrie Beilin, Rae-Chi Huang, Samantha J. Liew, Yong-Cai Chua, Xinyi Lin, Yonghui Wu, Graham C. Burdge, Cyrus Cooper, Hazel M. Inskip, Neerja Karnani, James C. Hopkins, Caroline E. Childs, Peter D. Gluckman, Nick Harvey, Mark A. Hanson, Joanna D. Holbrook, EpiGen Consortium, Keith M. Godfrey
19 Apr 2017 BMRC Singapore Institute for Clinical Sciences Gestational Diabetes Alters Functions in Offspring’s Umbilical Cord Cells With Implications for Cardiovascular Health Linh Nguyen, Adrian Kee Keong Teo, Cheng Wei Chang, Neerja Karnani, Kai Lyn Ng, Peter D. Gluckman, Yap Seng Chong, Walter Stunkel, Ajith Isaac Amrithraj, Anjaneyulu Kodali
7 Mar 2017 BMRC Singapore Institute for Clinical Sciences Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome Xinyi Lin, Ives Yubin Lim, Yonghui Wu, Ai Ling Teh, Li Chen, Izzuddin M. Aris, Shu E Soh, Mya Thway Tint, Julia L. MacIsaac, Alexander M. Morin, Fabian Yap, Kok Hian Tan, Seang Mei Saw, Michael S. Kobor, Michael J. Meaney, Keith M. Godfrey, Yap Seng Chong, Joanna D. Holbrook, Yung Seng Lee, Peter D. Gluckman, Neerja Karnani, GUSTO Study Group
8 Sep 2016 BMRC Singapore Institute for Clinical Sciences An Alternative Strategy for Pan-acetyl-lysine Antibody Generation Sun-Yee Kim, Choon Kiat Sim, Qiongyi Zhang, Hui Tang, Reinhard Brunmeir, Hong Pan, Neerja Karnani, Weiping Han, Kangling Zhang, Feng Xu
2 Aug 2016 BMRC Singapore Institute for Clinical Sciences Gene, Environment and Methylation (GEM): a tool suite to efficiently navigate large scale epigenome wide association studies and integrate genotype and interaction between genotype and environment Hong Pan, Joanna D. Holbrook, Neerja Karnani, Chee Keong Kwoh
22 Feb 2016 BMRC Singapore Institute for Clinical Sciences Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples Ai Ling Teh, Hong Pan, Xinyi Lin, Yubin Ives Lim, Chinari Pawan Kumar Pantro, Clara Yujing Cheong, Min Gong, Julia L. MacIsaac, Chee-Keong Kwoh, Michael J. Meaney, Michael S. Kobor, Yap-Seng Chong, Peter D. Gluckman, Joanna D. Holbrook, Neerja Karnani
20 Aug 2015 BMRC Singapore Institute for Clinical Sciences Rate of establishing the gut microbiota in infancy has consequences for future health Shaillay Dogra, Olga Sakwinska, Shu-E Soh, Catherine Ngom-Bru, Wolfram M. Brück, Bernard Berger, Harald Brüssow, Neerja Karnani, Yung Seng Lee, Fabian Yap, Yap-Seng Chong, Keith M. Godfrey, Joanna D. Holbrook
26 May 2015 BMRC Singapore Institute for Clinical Sciences HIF3A association with adiposity: the story begins before birth Hong Pan, Xinyi Lin, Yonghui Wu, Li Chen, Ai Ling Teh, Shu E Soh, Yung Seng Lee, Michael J. Meaney, Keith M. Godfrey, Mya Thway Tint, Julia L. MacIsaac, Alexander M. Morin, Kok Hian Tan, Fabian Yap, Seang Mei Saw, Michael S. Kobor, Yap-Seng Chong, Peter D. Gluckman, Neerja Karnani, Joanna D. Holbrook, GUSTO Study Group