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22 Jan 2024
SERC
Institute for Infocomm Research
Deep learning based CETSA feature prediction cross multiple cell lines with latent space representation
Shenghao Zhao,
Xulei Yang,
Zeng Zeng,
Peisheng Qian,
Ziyuan Zhao,
Lingyun Dai,
Nayana Prabhu,
Pär Nordlund,
Wai Leong Tam
Scientific Reports
8 Sep 2022
BMRC
Genome Institute of Singapore
CycleDNN - A Novel Deep Neural Network Model for CETSA Feature Prediction cross Cell Lines
Zeng Zeng,
Shenghao Zhao,
Qing Da,
Peisheng Qian,
Tam Wai Leong,
Lingyun Dai,
Pär Nordlund,
Nayana Prabhu,
Ziyuan Zhao,
Xulei Yang
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
8 Sep 2022
BMRC
Genome Institute of Singapore
CETSA Feature Based Clustering for Protein Outlier Discovery by Protein-to-Protein Interaction Prediction
Xulei Yang,
Qing Da,
Peisheng Qian,
Bharadwaj Veeravalli,
Tam Wai Leong,
Lingyun Dai,
Pär Nordlund,
Nayana Prabhu,
Ziyuan Zhao,
Zeng Zeng
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
14 Jul 2021
BMRC
Institute of Molecular and Cell Biology
CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity
Ying Yu Liang,
Smaranda Bacanu,
Lekshmy Sreekumar,
Anderson Daniel Ramos,
Lingyun Dai,
Martin Michaelis,
Jindrich Cinatl,
Takahiro Seki,
Yihai Cao,
Cynthia R. Coffill,
David P. Lane,
Nayana Prabhu,
Pär Nordlund
Cell Chemical Biology
3 Feb 2021
BMRC
Genome Institute of Singapore
Recent advances in proteome‐wide label‐free target deconvolution for bioactive small molecules
Jichao Sun,
Nayana Prabhu,
Jun Tang,
Fan Yang,
Lin Jia,
Jinan Guo,
Kefeng Xiao,
Wai Leong Tam,
Pär Nordlund,
Lingyun Dai
Medicinal Research Reviews
2 Apr 2019
BMRC
Institute of Molecular and Cell Biology
Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA)
Lingyun Dai,
Nayana Prabhu,
Liang Ying Yu,
Smaranda Bacanu,
Anderson Daniel Ramos,
Pär Nordlund
Annual Reviews
14 Mar 2019
BMRC
Institute of Molecular and Cell Biology
Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA
Wendi Sun,
Lingyun Dai,
Han Yu,
Brenda Puspita,
Tianyun Zhao,
Feng Li,
Justin L. Tan,
Yan Ting Lim,
Ming Wei Chen,
Radoslaw M. Sobota,
Daniel G. Tenen,
Nayana Prabhu,
Pär Nordlund
Redox Biology
26 Apr 2018
BMRC
Institute of Molecular and Cell Biology
Modulation of Protein-Interaction States through the Cell Cycle
Lingyun Dai,
Tianyun Zhao,
Xavier Bisteau,
Wendi Sun,
Nayana Prabhu,
Yan Ting Lim,
Radoslaw M. Sobota,
Philipp Kaldis,
Pär Nordlund
Cell
9 Mar 2018
BMRC
Institute of Molecular and Cell Biology
Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells
Chris Soon Heng Tan,
Ka Diam Go,
Xavier Bisteau,
Lingyun Dai,
Chern Han Yong,
Nayana Prabhu,
Mert Burak Ozturk,
Yan Ting Lim,
Lekshmy Sreekumar,
Johan Lengqvist,
Vinay Tergaonkar,
Philipp Kaldis,
Radoslaw M. Sobota,
Pär Nordlund
Science
19 Dec 2017
BMRC
Institute of Molecular and Cell Biology
Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality
Mayumi Kitagawa,
Pei-Ju Liao,
Kyung Hee Lee,
Jasmine Wong,
See Cheng Shang,
Noriaki Minami,
Oltea Sampetrean,
Hideyuki Saya,
Dai Lingyun,
Nayana Prabhu,
Go Ka Diam,
Radoslaw Sobota,
Andreas Larsson,
Pär Nordlund,
Frank McCormick,
Sujoy Ghosh,
David M. Epstein,
Brian W. Dymock,
Sang Hyun Lee
Nature Communications
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