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29 Aug 2023
BMRC
Skin Research Lab
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis
Kim Samirah Robinson,
Gee Ann Toh,
Muhammad Jasrie Firdaus,
Khek Chian Tham,
Pritisha Rozario,
Chrissie K. Lim,
Ying Xiu Toh,
Zhi Heng Lau,
Sophie Charlotte Binder,
Jacob Mayer,
Carine Bonnard,
Florian I. Schmidt,
John E.A. Common,
Franklin L. Zhong
Journal of Experimental Medicine
15 Jul 2022
BMRC
Skin Research Lab
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome
(Pending publish)
Kim S. Robinson,
Gee Ann Toh,
Pritisha Rozario,
Rae Chua,
Stefan Bauernfried,
Zijin Sun,
Muhammad Jasrie Firdaus,
Shima Bayat,
Rhea Nadkarni,
Zhi Sheng Poh,
Khek Chian Tham,
Cassandra R. Harapas,
Chrissie K. Lim,
Werncui Chu,
Celest W. S. Tay,
Kiat Yi Tan,
Tianyun Zhao,
Carine Bonnard,
Radoslaw Sobota,
John E. Connolly,
John Common,
Seth L. Masters,
Kaiwen W. Chen,
Lena Ho,
Bin Wu,
Veit Hornung,
Franklin L. Zhong
Science
1 Oct 2021
BMRC
Skin Research Lab
A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex
Tong San Tan,
John E. A. Common,
John S. Y. Lim,
Cedric Badowski,
Muhammad Jasrie Firdaus,
Steven S. Leonardi,
E. Birgitte Lane
Journal of Cell Science
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