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26 Dec 2022
BMRC
Institute of Bioengineering and Nanotechnology
Self-Assembled Daunorubicin/Epigallocatechin Gallate Nanocomplex for Synergistic Reversal of Chemoresistance in Leukemia
Ki Hyun Bae,
Fritz Lai,
Betul Oruc,
Motomi Osato,
Qingfeng Chen,
Motoichi Kurisawa
International Journal of Molecular Sciences
16 Nov 2022
BMRC
Institute of Molecular and Cell Biology,
Institute of Bioengineering and Bioimaging
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia
Ki Hyun Bae,
Fritz Lai,
Jamie Mong,
Akiko Niibori-Nambu,
Kiat Hwa Chan,
Zhisheng Her,
Motomi Osato,
Min-Han Tan,
Qingfeng Chen,
Motoichi Kurisawa
Journal of Nanobiotechnology
13 Dec 2019
BMRC
Institute of Molecular and Cell Biology
Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy
Ekta Khattar,
Kyaw Ze Ya Maung,
Chen Li Chew,
Arkasubhra Ghosh,
Michelle Meng Huang Mok,
Pei Lee,
Jun Zhang,
Wei Hong Jeff Chor,
Gökhan Cildir,
Chelsia Qiuxia Wang,
Nur Khairiah Mohd-Ismail,
Desmond Wai Loon Chin,
Soo Chin Lee,
Henry Yang,
Yong-Jae Shin,
Do-Hyun Nam,
Liming Chen,
Alan Prem Kumar,
Lih Wen Deng,
Masahito Ikawa,
Jayantha Gunaratne,
Motomi Osato,
Vinay Tergaonkar
Nature Communications
13 Nov 2019
BMRC
Institute of Bioengineering and Nanotechnology
A two-pronged anti-leukemic agent based on a hyaluronic acid–green tea catechin conjugate for inducing targeted cell death and terminal differentiation
Kun Liang,
Ki Hyun Bae,
Akiko Nambu,
Bibek Dutta,
Joo Eun Chung,
Motomi Osato,
Motoichi Kurisawa
Biomaterials Science
14 Aug 2017
BMRC
Institute of Molecular and Cell Biology
Ikk2 regulates cytokinesis during vertebrate development
Hongyuan Shen,
Eun Myoung Shin,
Serene Lee,
Sinnakaruppan Mathavan,
Hiromi Koh,
Motomi Osato,
Hyungwon Choi,
Vinay Tergaonkar,
Vladimir Korzh
Scientific Reports
11 May 2015
BMRC
Institute of Molecular and Cell Biology
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
(Pending publish)
Cheryl M. Koh,
Marco Bezzi,
Diana H. P. Low,
Wei Xia Ang,
Shun Xie Teo,
Florence P. H. Gay,
Muthafar Al-Haddawi,
Soo Yong Tan,
Motomi Osato,
Arianna Sabò,
Bruno Amati,
Keng Boon Wee,
Ernesto Guccione
Nature
22 Jan 2015
BMRC
Institute of Molecular and Cell Biology
Bimodal Influence of Vitamin D in Host Response to Systemic Candida Infection—Vitamin D Dose Matters
Sharada Ravikumar,
Joan Hui Juan Lim,
Yan-Ming Wang,
Thomas Paulraj Thamboo,
Lufei Chengchen,
Lizhen Ong,
Jinmiao Chen,
Jessamine Geraldine Goh,
Sen Hee Tay,
Mar Soe Win,
Winnie Leong,
Wee Joo Chng,
Motomi Osato,
Mihai G. Netea,
Yue Wang,
Louis Yi Ann Chai,
Ai Leng Khoo,
Titus Lau,
Roger Foo,
Haris Mirza,
Kevin Shyong Wei Tan,
Sunil Sethi
Journal of Infectious Diseases
18 Nov 2014
BMRC
Institute of Molecular and Cell Biology
Characterization of the Runx Gene Family in a Jawless Vertebrate, the Japanese Lamprey (Lethenteron japonicum)
Giselle Sek Suan Nah,
Boon-Hui Tay,
Sydney Brenner,
Motomi Osato,
Byrappa Venkatesh,
Nikolas Nikolaidis
PLoS ONE
7 Aug 2014
BMRC
Institute of Molecular and Cell Biology
Disruption of Runx1 and Runx3 Leads to Bone Marrow Failure and Leukemia Predisposition due to Transcriptional and DNA Repair Defects
Chelsia Qiuxia Wang,
Vaidehi Krishnan,
Lavina Sierra Tay,
Desmond Wai Loon Chin,
Cai Ping Koh,
Jing Yuan Chooi,
Giselle Sek Suan Nah,
Linsen Du,
Bindya Jacob,
Namiko Yamashita,
Soak Kuan Lai,
Tuan Zea Tan,
Seiichi Mori,
Ichiro Tanuichi,
Vinay Tergaonkar,
Yoshiaki Ito,
Motomi Osato
Cell Reports
2 May 2014
BMRC
Institute of Molecular and Cell Biology
RUNX1 point mutations potentially identify a subset of early immature T-cell acute lymphoblastic leukaemia that may originate from differentiated T-cells
Michelle Meng Huang Mok,
Linsen Du,
Chelsia Qiuxia Wang,
Vinay Tergaonkar,
Te Chih Liu,
Shirley Kow Yin Kham,
Takaomi Sanda,
Allen Eng-Juh Yeoh,
Motomi Osato
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