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15 Sep 2022
BMRC
Institute of Bioengineering and Bioimaging
Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans
Shiqi Zhong,
Raphael Chevre,
David Castaño Mayan,
Maria Corlianò,
Blake J. Cochran,
Kai Ping Sem,
Theo H. van Dijk,
Jianhe Peng,
Liang Juin Tan,
Siddesh V. Hartimath,
Boominathan Ramasamy,
Peter Cheng,
Albert K. Groen,
Folkert Kuipers,
Julian L. Goggi,
Chester Drum,
Rob M. van Dam,
Ru San Tan,
Kerry-Anne Rye,
Michael R. Hayden,
Ching-Yu Cheng,
Shaji Chacko,
Jason Flannick,
Xueling Sim,
Hong Chang Tan,
Roshni R. Singaraja
Journal of Clinical Investigation
16 Aug 2016
BMRC
Translational Laboratory in Genetic Medicine
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
Marta Garcia-Miralles,
Xin Hong,
Liang Juin Tan,
Nicholas S. Caron,
Yihui Huang,
Xuan Vinh To,
Rachel Yanping Lin,
Sonia Franciosi,
Spyros Papapetropoulos,
Liat Hayardeny,
Michael R. Hayden,
Kai-Hsiang Chuang,
Mahmoud A. Pouladi
Scientific Reports
28 Apr 2016
BMRC
Translational Laboratory in Genetic Medicine
Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease
Reshmi Rajendran,
Arianna Novati,
Carsten Calaminus,
Olaf Riess,
Michael R. Hayden,
Huu P. Nguyen,
Roy Tang Yi Teo,
Xin Hong,
Libo Yu-Taeger,
Yihui Huang,
Liang Juin Tan,
Yuanyun Xie,
Xuan Vinh To,
Ling Guo,
Kai-Hsiang Chuang,
Mahmoud A. Pouladi
Human Molecular Genetics
11 Feb 2016
BMRC
Translational Laboratory in Genetic Medicine
Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD
Dagmar E. Ehrnhoefer,
Jenny Russ,
Sean-Patrick Riechers,
Stefanie Butland,
Yu Deng,
Niels Skotte,
Jean Laine,
Melissa Laroche,
Mahmoud A. Pouladi,
Erich E. Wanker,
Michael R. Hayden,
Rona K. Graham
Human Molecular Genetics
26 Jan 2016
BMRC
Translational Laboratory in Genetic Medicine
Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease
Marta Garcia-Miralles,
Jolene Ooi,
Costanza Ferrari Bardile,
Liang Juin Tan,
Maya George,
Chester L. Drum,
Rachel Yanping Lin,
Michael R. Hayden,
Mahmoud A. Pouladi
Experimental Neurology
15 Nov 2014
BMRC
Translational Laboratory in Genetic Medicine
Inhibition of Excessive Monoamine Oxidase A/B Activity Protects Against Stress-induced Neuronal Death in Huntington Disease
Jolene Ooi,
Michael R. Hayden,
Mahmoud A. Pouladi
Molecular Neurobiology
20 Sep 2013
BMRC
Translational Laboratory in Genetic Medicine
Choosing an animal model for the study of Huntington's disease
(Pending publish)
Mahmoud A. Pouladi,
A. Jennifer Morton,
Michael R. Hayden
Nature Reviews Neuroscience
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