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15 Feb 2024
Others
Experimental Drug Development Centre
Identification of small‐molecule binding sites of a ubiquitin‐conjugating enzyme‐UBE2T through fragment‐based screening
Yong Yao Loh,
Jothi Anantharajan,
Qiwei Huang,
Weijun Xu,
Justina Fulwood,
Hui Qi Ng,
Elizabeth Yihui Ng,
Chong Yu Gea,
Meng Ling Choong,
Qian Wen Tan,
Xiaoying Koh,
Wan Hsin Lim,
Kassoum Nacro,
Joseph Cherian,
Nithya Baburajendran,
Zhiyuan Ke,
CongBao Kang
Protein Science
8 May 2018
Others
Experimental Drug Development Centre
Phenotypic screening for inhibitors of a mutant thrombopoietin receptor
Anna Ngo,
Ann Koay,
Christian Pecquet,
Meng Ling Choong,
Carmen Diaconu,
David Jenkins,
Andrew Shiau,
Stefan Constantinescu
Methods in Molecular Biology
23 Apr 2018
BMRC
Bioinformatics Institute
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia
Haiyan Yang,
Lohitha Rao Chennamaneni,
Melvyn Wai Tuck Ho,
Shi Hua Ang,
Eldwin Sum Wai Tan,
Duraiswamy Athisayamani Jeyaraj,
Yoon Sheng Yeap,
Boping Liu,
Esther Hq Ong,
Joma Kanikadu Joy,
John Liang Kuan Wee,
Perlyn Kwek,
Priya Retna,
Nurul Dinie,
Thuy Thi Hanh Nguyen,
Shi Jing Tai,
Vithya Manoharan,
Vishal Pendharkar,
Choon Bing Low,
Yun Shan Chew,
Susmitha Vuddagiri,
Kanda Sangthongpitag,
Meng Ling Choong,
May Ann Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Anders Poulsen,
Sharon Lim,
Charles Chuah,
Tiong Sin Ong,
Jeffrey Hill,
Alex Matter,
Kassoum Nacro
Journal of Medicinal Chemistry
18 Oct 2016
Others
Experimental Drug Development Centre
A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms.
Zhufang Ann Koay,
Christian Pecquet,
Carmen Diaconu,
Yasmine Ould-Amer,
CongBao Kang,
Anders Poulsen,
May Ann Lee,
David Jenkins,
Andrew Shiau,
Stefan Constantinescu,
Anna Ngo,
Meng Ling Choong
Combinatorial Chemistry & High Throughput Screening
24 Mar 2016
Others
Experimental Drug Development Centre
Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 & 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells
Kassoum Nacro,
Zhi Ying Poh,
Samantha Guo,
Joseph Cherian,
Duraiswamy Jeyaraj,
Yun Xuan Wong,
Melvyn Ho,
Hai Yan Yang,
Joma Kanikadu Joy,
Zekui Perlyn Kwek,
Boping Liu,
John Laing Kuan Wee Wee,
Esther Hq Ong,
Meng Ling Choong,
Anders Poulsen,
May Ann Lee,
Vishal Pendharkar,
Vithya Manoharan,
Yun Shan Chew,
Kanda Sangthongpitag,
Sharon Lim,
S. Tiong Ong,
Jeffrey Hill,
Thomas H. Keller
Journal of Medicinal Chemistry
10 Mar 2016
Others
Experimental Drug Development Centre
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants
Ilyas Chachoua,
Christian Pecquet,
Mira El-Khoury,
Harini Nivarthi,
Roxana-Irina Albu,
Caroline Marty,
Vitalina Gryshkova,
Jean-Philippe Defour,
Gaelle Vertenoeil,
Anna Ngo,
Ann Koay,
Hana Raslova,
Meng Ling Choong,
Robert Kralovics,
Stefan N. Constantinescu
Blood
30 Jun 2014
Others
Experimental Drug Development Centre
Establishment and Characterization of a Singaporean Chinese Lung Adenocarcinoma Cell Line with Four Copies of the Epidermal Growth Factor Receptor Gene
Meng Ling Choong,
Jacklyn Yong,
Yu Wang,
May Ann Lee
BioResearch Open Access
1 Sep 2009
Others
Experimental Drug Development Centre
Specific activation of the p53 pathway by low dose actinomycin D: A new route to p53 based cyclotherapy
Meng Ling Choong,
Henry Yang,
May Ann Lee,
David P. Lane
Cell Cycle
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