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24 Oct 2023
Others
Experimental Drug Development Centre
Targeted Degradation of XIAP is Sufficient and Specific to Induce Apoptosis in MYCN-overexpressing High-risk Neuroblastoma
Zhang'E Choo,
Xiaoying Koh,
Megan Rui En Wong,
Ruth Minothini Ashokan,
Nurul Suhana Binte Ali Ahamed,
CongBao Kang,
Chik Hong Kuick,
Kenneth Tou En Chang,
Sarit Larisch,
Amos Hong Pheng Loh,
Zhi Xiong Chen
Cancer Research Communications
18 Aug 2023
BMRC
Institute of Molecular and Cell Biology
Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
(Pending publish)
Amos Hong Pheng Loh,
Min Thura,
Abhishek Gupta,
Sheng Hui Tan,
Kelvin Kam Yew Kuan,
Koon Hwee Ang,
Khurshid Merchant,
Kenneth Tou En Chang,
Hui Yi Yon,
Yong Chen,
Mathew Hern Wang Cheng,
Arjandas Mahadev,
Matthew Chau Hsien Ng,
Michaela Su-Fern Seng,
Prasad Iyer,
Pei Ling Chia,
Shui Yen Soh,
Qi Zeng
Molecular Therapy - Oncolytics
15 Oct 2020
BMRC
Institute of Molecular and Cell Biology
Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics
Kylie Su Mei Yong,
Zhisheng Her,
Sue Yee Tan,
Wilson Wei Sheng Tan,
Min Liu,
Fritz Lai,
Shi Min Heng,
Yong Fan,
Kenneth Tou En Chang,
Cheng-I Wang,
Jerry Kok Yen Chan,
Jianzhu Chen,
Qingfeng Chen
Frontiers in Immunology
11 Sep 2020
BMRC
Institute of Molecular and Cell Biology
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Zhisheng Her,
Joel Heng Loong Tan,
Yee-Siang Lim,
Sue Yee Tan,
Xue Ying Chan,
Wilson Wei Sheng Tan,
Min Liu,
Kylie Su Mei Yong,
Fritz Lai,
Erica Ceccarello,
Zhiqiang Zheng,
Yong Fan,
Kenneth Tou En Chang,
Lei Sun,
Shih Chieh Chang,
Chih-Liang Chin,
Guan Huei Lee,
Yock Young Dan,
Yun-Shen Chan,
Seng Gee Lim,
Jerry Kok Yen Chan,
K. George Chandy,
Qingfeng Chen
Frontiers in Immunology
17 Jan 2019
BMRC
Institute of Molecular and Cell Biology
Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Qingfeng Chen,
Yanyan Ke,
Wai Nam Liu,
Zhisheng Her,
Min Liu,
Sue Yee Tan,
Yong Wah Tan,
Xue Ying Chan,
Yong Fan,
Edwin Kunxiang Huang,
Huiyi Chen,
Kenneth Tou En Chang,
Jerry Kok Yen Chan,
Justin Jang Hann Chu
Journal of Virology
17 Jan 2019
BMRC
Institute of Molecular and Cell Biology
Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice
Sue Yee Tan,
Yong Wah Tan,
Xue Ying Chan,
Yong Fan,
Edwin Kunxiang Huang,
Yanyan Ke,
Wai Nam Liu,
Zhisheng Her,
Min Liu,
Huiyi Chen,
Kenneth Tou En Chang,
Jerry Kok Yen Chan,
Justin Jang Hann Chu,
Qingfeng Chen
Journal of Virology
30 Mar 2018
BMRC
Institute of Molecular and Cell Biology
Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy
Seng Gee Lim,
Qingfeng Chen,
Yue Zhao,
Timothy Wai Ho Shuen,
Tan Boon Toh,
Xue Ying Chan,
Min Liu,
Sue Yee Tan,
Yong Fan,
Hechuan Yang,
Shridhar Ganpathi Lyer,
Glenn Kunnath Bonney,
Eva Loh,
Kenneth Tou En Chang,
Thiam Chye Tan,
Weiwei Zhai,
Jerry Kok Yen Chan,
Edward Kai-Hua Chow,
Cheng Ean Chee,
Guan Huei Lee,
Yock Young Dan,
Pierce Kah-Hoe Chow,
Han Chong Toh
Gut
30 Nov 2017
BMRC
Institute of Molecular and Cell Biology
A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice
Merry Gunawan,
Zhisheng Her,
Min Liu,
Sue Yee Tan,
Xue Ying Chan,
Wilson Wei Sheng Tan,
Shubasree Dharmaraaja,
Yong Fan,
Chee Bing Ong,
Eva Loh,
Kenneth Tou En Chang,
Thiam Chye Tan,
Jerry Kok Yen Chan,
Qingfeng Chen
Scientific Reports
12 Sep 2017
BMRC
Institute of Molecular and Cell Biology
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma
Xiaosai Yao,
Jing Tan,
Kevin Junliang Lim,
Joanna Koh,
Wen Fong Ooi,
Zhimei Li,
Dachuan Huang,
Manjie Xing,
Yang Sun Chan,
James Zhengzhong Qu,
Su Ting Tay,
Giovani Wijaya,
Yue Ning Lam,
Jing Han Hong,
Ai Ping Lee-Lim,
Peiyong Guan,
Michelle Shu Wen Ng,
Cassandra Zhengxuan He,
Joyce Suling Lin,
Tannistha Nandi,
Aditi Qamra,
Chang Xu,
Swe Swe Myint,
James O. J. Davies,
Jian Yuan Goh,
Gary Loh,
Bryan C. Tan,
Steven G. Rozen,
Qiang Yu,
Iain Bee Huat Tan,
Christopher Wai Sam Cheng,
Shang Li,
Kenneth Tou En Chang,
Puay Hoon Tan,
David Lawrence Silver,
Alexander Lezhava,
Gertrud Steger,
Jim R. Hughes,
Bin Tean Teh,
Patrick Tan
Cancer Discovery
8 Sep 2017
BMRC
Institute of Molecular and Cell Biology
Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model
Zhiqiang Zheng,
Ching Wooen Sze,
Choong Tat Keng,
Muthafar Al-Haddawi,
Min Liu,
Sue Yee Tan,
Hwee Ling Kwek,
Zhisheng Her Her,
Xue Ying Chan,
Bhaskar Barnwal,
Eva Loh,
Kenneth Tou En Chang,
Thiam Chye Tan,
Yee-Joo Tan,
Qingfeng Chen
PLOS ONE
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