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25 Mar 2021
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BMRC
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Institute of Molecular and Cell Biology
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Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells
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Erica Ceccarello,
Tommaso Tabaglio,
Sarene Koh,
Vincent Oei,
Winnie Teo,
Owen Julianto Jonathan,
Andrea Pavesi,
Qingfeng Chen,
Antonio Bertoletti,
Keng Boon Wee,
Ernesto Guccione
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Nucleic Acid Therapeutics
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7 Sep 2018
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BMRC
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Institute of Molecular and Cell Biology
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MBNL1 alternative splicing isoforms play opposing roles in cancer
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Tommaso Tabaglio,
Diana HP Low,
Winnie Koon Lay Teo,
Pierre Alexis Goy,
Piotr Cywoniuk,
Heike Wollmann,
Jessica Ho,
Damien Tan,
Joey Aw,
Andrea Pavesi,
Krzysztof Sobczak,
Dave Keng Boon Wee,
Ernesto Guccione
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Life Science Alliance
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9 Jul 2018
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BMRC
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Bioinformatics Institute
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PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells
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Suchira Gallage,
Marco Seehawer,
Thomas Carroll,
Gopuraja Dharmalingam,
Athena Georgilis,
Sabrina Klotz,
Christopher J. Hanley,
Nicolas Herranz,
Benedikt Weirich,
Beatriz Morancho,
Ana Carolina Leote,
Luana D'Artista,
Keng Boon Wee,
Marco Mellone,
Joaquim Pombo,
Danijela Heide,
Ernesto Guccione,
Joaquín Arribas,
Nuno L. Barbosa-Morais,
Mathias Heikenwalder,
Gareth J. Thomas,
Lars Zender,
Jesús Gil
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Cancer Cell
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9 Jul 2018
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BMRC
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Institute of Molecular and Cell Biology
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PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells
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Athena Georgilis,
Sabrina Klotz,
Christopher J. Hanley,
Nicolas Herranz,
Benedikt Weirich,
Beatriz Morancho,
Ana Carolina Leote,
Luana D'Artista,
Suchira Gallage,
Marco Seehawer,
Thomas Carroll,
Gopuraja Dharmalingam,
Keng Boon Wee,
Marco Mellone,
Joaquim Pombo,
Danijela Heide,
Ernesto Guccione,
Joaquín Arribas,
Nuno L. Barbosa-Morais,
Mathias Heikenwalder,
Gareth J. Thomas,
Lars Zender,
Jesús Gil
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Cancer Cell
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19 Jun 2018
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BMRC
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Bioinformatics Institute
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SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements
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Dang Vinh Do,
Bernhard Strauss,
Engin Cukuroglu,
Iain Macaulay,
Keng Boon Wee,
Tim Xiaoming Hu,
Ruiz De Los Mozos Igor,
Caroline Lee,
Andrew Harrison,
Richard Butler,
Sabine Dietmann,
Ule Jernej,
John Marioni,
Christopher W. J. Smith,
Jonathan Göke,
M. Azim Surani
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Cell Discovery
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28 Oct 2017
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BMRC
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Institute of Molecular and Cell Biology
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Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma
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Jing Lin,
Jia Hui Jane Lee,
Kathirvel Paramasivam,
Elina Pathak,
Zhenxun Wang,
Zacharias Aloysius Dwi Pramono,
Bing Lim,
Keng Boon Wee,
Uttam Surana
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Molecular Therapy Nucleic Acids
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21 Jun 2016
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BMRC
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Bioinformatics Institute
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RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming
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Cheng-Xu Delon Toh,
Jun-Wei Chan,
Zheng-Shan Chong,
Hao Fei Wang,
Hong Chao Guo,
Sandeep Satapathy,
Dongrui Ma,
Germaine Yen Lin Goh,
Ekta Khattar,
Lin Yang,
Vinay Tergaonkar,
Young-Tae Chang,
James J. Collins,
George Q. Daley,
Keng Boon Wee,
Chadi A. EL Farran,
Hu Li,
Yoon-Pin Lim,
Frederic A. Bard,
Yuin-Han Loh
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Cell Reports
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15 Jan 2016
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BMRC
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Bioinformatics Institute
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Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance
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Keng Boon Wee,
Raphael Tze Chuen Lee,
Jing Lin,
Zacharias Aloysius Dwi Pramono,
Sebastian Maurer-Stroh
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PLOS Computational Biology
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11 May 2015
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BMRC
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Institute of Molecular and Cell Biology
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MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis (Pending publish)
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Cheryl M. Koh,
Marco Bezzi,
Diana H. P. Low,
Wei Xia Ang,
Shun Xie Teo,
Florence P. H. Gay,
Muthafar Al-Haddawi,
Soo Yong Tan,
Motomi Osato,
Arianna Sabò,
Bruno Amati,
Keng Boon Wee,
Ernesto Guccione
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Nature
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