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Publication date Communities Collections Article title Author(s) Journal/Conference
19 Feb 2025 BMRC Institute of Molecular & Cell Biology Developing splice-switching oligonucleotides for urea cycle disorder using an integrated diagnostic and therapeutic platform (Pending publish) Jin Rong Ow, Eri Imagawa, Feng Chen, Wei Yuan Cher, Shermin Yu Tung Chan, Rajasekhar Reddy Gurrampati, Venkataramanan Ramadass, Mun Fai Loke, Tommaso Tabaglio, Hikaru Nishida, Toshiki Tsunogai, Masahide Yazaki, Gaik Siew Ch’ng, Manikandan Lakshmanan, Su Seong Lee, Jackie Y. Ying, Ernesto Guccione, Kimihiko Oishi, Keng Boon Wee Journal of Hepatology
7 Jan 2025 BMRC Institute of Molecular and Cell Biology Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform (Pending publish) Tommaso Tabaglio, Taniya Agarwal, Wei Yuan Cher, Jin Rong Ow, Ah Keng Chew, Priscila Yun Qian Sun, Raja Sekhar Reddy Gurrampati, Hongfang Lu, Praveena Naidu, Hong Kai Ng, Xavier Le Guezennec, Shi Yan Ng, Manikandan Lakshmanan, Ernesto Guccione, Keng Boon Wee Molecular Therapy Nucleic Acids
25 Mar 2021 BMRC Institute of Molecular and Cell Biology Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells Erica Ceccarello, Tommaso Tabaglio, Sarene Koh, Vincent Oei, Winnie Teo, Owen Julianto Jonathan, Andrea Pavesi, Qingfeng Chen, Antonio Bertoletti, Keng Boon Wee, Ernesto Guccione Nucleic Acid Therapeutics
7 Sep 2018 BMRC Institute of Molecular and Cell Biology MBNL1 alternative splicing isoforms play opposing roles in cancer Tommaso Tabaglio, Diana HP Low, Winnie Koon Lay Teo, Pierre Alexis Goy, Piotr Cywoniuk, Heike Wollmann, Jessica Ho, Damien Tan, Joey Aw, Andrea Pavesi, Krzysztof Sobczak, Dave Keng Boon Wee, Ernesto Guccione Life Science Alliance
9 Jul 2018 BMRC Institute of Molecular and Cell Biology PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells Athena Georgilis, Sabrina Klotz, Christopher J. Hanley, Nicolas Herranz, Benedikt Weirich, Beatriz Morancho, Ana Carolina Leote, Luana D'Artista, Suchira Gallage, Marco Seehawer, Thomas Carroll, Gopuraja Dharmalingam, Keng Boon Wee, Marco Mellone, Joaquim Pombo, Danijela Heide, Ernesto Guccione, Joaquín Arribas, Nuno L. Barbosa-Morais, Mathias Heikenwalder, Gareth J. Thomas, Lars Zender, Jesús Gil Cancer Cell
9 Jul 2018 BMRC Bioinformatics Institute PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells Suchira Gallage, Marco Seehawer, Thomas Carroll, Gopuraja Dharmalingam, Athena Georgilis, Sabrina Klotz, Christopher J. Hanley, Nicolas Herranz, Benedikt Weirich, Beatriz Morancho, Ana Carolina Leote, Luana D'Artista, Keng Boon Wee, Marco Mellone, Joaquim Pombo, Danijela Heide, Ernesto Guccione, Joaquín Arribas, Nuno L. Barbosa-Morais, Mathias Heikenwalder, Gareth J. Thomas, Lars Zender, Jesús Gil Cancer Cell
19 Jun 2018 BMRC Bioinformatics Institute SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements Dang Vinh Do, Bernhard Strauss, Engin Cukuroglu, Iain Macaulay, Keng Boon Wee, Tim Xiaoming Hu, Ruiz De Los Mozos Igor, Caroline Lee, Andrew Harrison, Richard Butler, Sabine Dietmann, Ule Jernej, John Marioni, Christopher W. J. Smith, Jonathan Göke, M. Azim Surani Cell Discovery
28 Oct 2017 BMRC Institute of Molecular and Cell Biology Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma Jing Lin, Jia Hui Jane Lee, Kathirvel Paramasivam, Elina Pathak, Zhenxun Wang, Zacharias Aloysius Dwi Pramono, Bing Lim, Keng Boon Wee, Uttam Surana Molecular Therapy Nucleic Acids
21 Jun 2016 BMRC Bioinformatics Institute RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming Cheng-Xu Delon Toh, Jun-Wei Chan, Zheng-Shan Chong, Hao Fei Wang, Hong Chao Guo, Sandeep Satapathy, Dongrui Ma, Germaine Yen Lin Goh, Ekta Khattar, Lin Yang, Vinay Tergaonkar, Young-Tae Chang, James J. Collins, George Q. Daley, Keng Boon Wee, Chadi A. EL Farran, Hu Li, Yoon-Pin Lim, Frederic A. Bard, Yuin-Han Loh Cell Reports
15 Jan 2016 BMRC Bioinformatics Institute Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance Keng Boon Wee, Raphael Tze Chuen Lee, Jing Lin, Zacharias Aloysius Dwi Pramono, Sebastian Maurer-Stroh PLOS Computational Biology