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4 Oct 2024
BMRC
Bioprocessing Technology Institute
Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research
Ryan Haryadi,
Kah Fai Chan,
Pao Chun Lin,
Yun Lei Tan,
Corrine Wan,
Wahyu Shahreel,
Shi Jie Tay,
Terry Nguyen-Khuong,
Ian Walsh,
Zhiwei Song
Scientific Reports
7 May 2021
BMRC
Bioprocessing Technology Institute
Production of Highly Sialylated Recombinant Glycoproteins Using Ricinus communis Agglutinin-I-Resistant CHO Glycosylation Mutants
John S. Y. Goh,
Kah Fai Chan,
Zhiwei Song
Methods in Molecular Biology
4 Jun 2019
BMRC
Bioprocessing Technology Institute
Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics
Pao-Chun Lin,
Kah Fai Chan,
Irene A. Kiess,
Joselyn Tan,
Wahyu Shahreel,
Sze-Yue Wong,
Zhiwei Song
mAbs
7 May 2018
BMRC
Bioprocessing Technology Institute
The “less-is-more” in therapeutic antibodies: Afucosylated anti-cancer antibodies with enhanced antibody-dependent cellular cytotoxicity
Natasha A. Pereira,
Kah Fai Chan,
Pao Chun Lin,
Zhiwei Song
mAbs
16 Oct 2015
BMRC
Bioprocessing Technology Institute
Inactivation of GDP-fucose transporter gene (Slc35c1) in CHO cells by ZFNs, TALENs and CRISPR-Cas9 for production of fucose-free antibodies
Kah Fai Chan,
Wahyu Shahreel,
Corrine Wan,
Gavin Teo,
Noor Hayati,
Shi Jie Tay,
Wen Han Tong,
Yuansheng Yang,
Pauline M. Rudd,
Peiqing Zhang,
Zhiwei Song
Biotechnology Journal
9 Jun 2014
BMRC
Bioprocessing Technology Institute
Producing recombinant therapeutic glycoproteins with enhanced sialylation using CHO-gmt4 glycosylation mutant cells
John SY Goh,
Yingwei Liu,
Kah Fai Chan,
Corrine Wan,
Gavin Teo,
Peiqing Zhang,
Yuanxing Zhang,
Zhiwei Song
Bioengineered
10 Dec 2013
BMRC
Bioprocessing Technology Institute
Highly sialylated recombinant human erythropoietin production in large-scale perfusion bioreactor utilizing CHO-gmt4 (JW152) with restored GnT I function
John S. Y. Goh,
Yingwei Liu,
Haifeng Liu,
Kah Fai Chan,
Corrine Wan,
Gavin Teo,
Xiangshan Zhou,
Fusheng Xie,
Peiqing Zhang,
Yuanxing Zhang,
Zhiwei Song
Biotechnology Journal
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