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10 Jul 2019
BMRC
Institute of Molecular and Cell Biology
TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner
Teja Celhar,
Hao Kim Lu,
Lia Benso,
Larissa Rakhilina,
Hui Yin Lee,
Shubhita Tripathi,
Olga Zharkova,
Wei Yee Ong,
Hiroko Yasuga,
Bijin Au,
Damien Marlier,
Lina Hsiu Kim Lim,
Thomas Paulraj Thamboo,
John S. Mudgett,
Matthew F. Mackey,
Dennis M. Zaller,
John E. Connolly,
Anna-Marie Fairhurst
Frontiers in Immunology
22 Feb 2019
BMRC
Singapore Immunology Network
Enhancing Antigen Cross-Presentation in Human Monocyte-Derived Dendritic Cells by Recruiting the Intracellular Fc Receptor TRIM21
Patricia M. L. Ng,
Nivashini Kaliaperumal,
Chia Yin Lee,
Wen Jie Chin,
Hwee Ching Tan,
Veonice B. Au,
Angeline X. -H. Goh,
Qiao Wen Tan,
Darren S. G. Yeo,
John E. Connolly,
Cheng-I Wang
The Journal of Immunology
20 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine
David A. G. Skibinski,
Leigh Ann Jones,
Yuan O. Zhu,
Lin Wu Xue,
Bijin Au,
Bernett Lee,
Ahmad Nazri Mohamed Naim,
Audrey Lee,
Nivashini Kaliaperumal,
Jenny G. H. Low,
Lawrence S. Lee,
Michael Poidinger,
Philippe Saudan,
Martin Bachmann,
Eng Eong Ooi,
Brendon J. Hanson,
Veronica Novotny-Diermayr,
Alex Matter,
Anna-Marie Fairhurst,
Martin L. Hibberd,
John E. Connolly
Scientific Reports
5 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
Franklin L. Zhong,
Kim Robinson,
Daniel Eng Thiam Teo,
Kiat-Yi Tan,
Chrissie Lim,
Cassandra R. Harapas,
Chien-Hsiung Yu,
William H. Xie,
Radoslaw M. Sobota,
Veonice Bijin Au,
Richard Hopkins,
Andrea D'Osualdo,
John C. Reed,
John E. Connolly,
Seth L. Masters,
Bruno Reversade
Journal of Biological Chemistry
1 Nov 2018
BMRC
Institute of Molecular and Cell Biology
Autophagy Governs Protumorigenic Effects of Mitotic Slippage–induced Senescence
Rekha Jakhar,
Monique N.H. Luijten,
Alex X.F. Wong,
Bing Cheng,
Ke Guo,
Suat P. Neo,
Bijin Au,
Madhura Kulkarni,
Kah J. Lim,
Jiamila Maimaiti,
Han C. Chong,
Elaine H. Lim,
Tee B.K. Tan,
Kong W. Ong,
Yirong Sim,
Jill S.L. Wong,
James B.K. Khoo,
Juliana T.S. Ho,
Boon T. Chua,
Indrajit Sinha,
Xiaomeng Wang,
John E. Connolly,
Jayantha Gunaratne,
Karen C. Crasta
Molecular Cancer Research
24 Sep 2018
BMRC
Institute of Molecular and Cell Biology
Distinct “Immunoallertypes” of Disease and High Frequencies of Sensitization in Non–Cystic Fibrosis Bronchiectasis
Micheál Mac Aogáin,
Pei Yee Tiew,
Albert Yick Hou Lim,
Teck Boon Low,
Gan Liang Tan,
Tidi Hassan,
Thun How Ong,
Sze Lei Pang,
Zi Yang Lee,
Xiao Wei Gwee,
Christopher Martinus,
Yang Yie Sio,
Sri Anusha Matta,
Tan Ching Ong,
Yuen Seng Tiong,
Kang Ning Wong,
Sriram Narayanann,
Veonice Bijin Au,
Damien Marlier,
Holly R. Keir,
Augustine Tee,
John Arputhan Abisheganaden,
Mariko Siyue Koh,
De Yun Wang,
John E. Connolly,
Fook Tim Chew,
James D. Chalmers,
Sanjay H. Chotirmall
American Journal of Respiratory and Critical Care Medicine
27 Jul 2018
BMRC
Institute of Molecular and Cell Biology
Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study
Micheál Mac Aogáin,
Ravishankar Chandrasekaran,
Albert Yick Hou Lim,
Teck Boon Low,
Gan Liang Tan,
Tidi Hassan,
Thun How Ong,
Amanda Hui Qi Ng,
Denis Bertrand,
Jia Yu Koh,
Sze Lei Pang,
Zi Yang Lee,
Xiao Wei Gwee,
Christopher Martinus,
Yang Yie Sio,
Sri Anusha Matta,
Fook Tim Chew,
Holly R. Keir,
John E. Connolly,
John Arputhan Abisheganaden,
Mariko Siyue Koh,
Niranjan Nagarajan,
James D. Chalmers,
Sanjay H. Chotirmall
European Respiratory Journal
28 Apr 2018
BMRC
Institute of Molecular and Cell Biology
Toll‐Like Receptor 9 Deficiency Breaks Tolerance to RNA‐Associated Antigens and Up‐Regulates Toll‐Like Receptor 7 Protein in Sle1 Mice
Teja Celhar,
Hiroko Yasuga,
Hui Yin Lee,
Olga Zharkova,
Shubhita Tripathi,
Susannah I. Thornhill,
Hao K. Lu,
Bijin Au,
Lina H. K. Lim,
Thomas P. Thamboo,
Shizuo Akira,
Edward K. Wakeland,
John E. Connolly,
Anna‐Marie Fairhurst
Arthritis & Rheumatology
12 Jul 2016
BMRC
Skin Research Lab
Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare
(Pending publish)
Kern Rei Chng,
Angeline Su Ling Tay,
Chenhao Li,
Amanda Hui Qi Ng,
Jingjing Wang,
Bani Kaur Suri,
Sri Anusha Matta,
Naomi McGovern,
Baptiste Janela,
Xuan Fei Colin C. Wong,
Yang Yie Sio,
Bijin Veonice Au,
Andreas Wilm,
Paola Florez De Sessions,
Thiam Chye Lim,
Mark Boon Yang Tang,
Florent Ginhoux,
John E. Connolly,
E. Birgitte Lane,
Fook Tim Chew,
John E. A. Common,
Niranjan Nagarajan
Nature Microbiology
13 Nov 2015
BMRC
Institute of Molecular and Cell Biology
TLR7 and TLR9 ligands regulate antigen presentation by macrophages
Teja Celhar,
Selma Pereira-Lopes,
Susannah I. Thornhill,
Hui Yin Lee,
Manprit K. Dhillon,
Michael Poidinger,
John E. Connolly,
Lina H. K. Lim,
Subhra K. Biswas,
Anna-Marie Fairhurst
International Immunology
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