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10 Jan 2018
BMRC
Singapore Institute for Clinical Sciences
DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up
Kieran J. O'Donnell,
Li Chen,
Julia L. MacIsaac,
Lisa M. McEwen,
Thao Nguyen,
Katherine Beckmann,
Yuecai Zhu,
Lawrence Ming Chen,
Jeanne Brooks-Gunn,
David Goldman,
Elena L. Grigorenko,
James F. Leckman,
Josie Diorio,
Neerja Karnani,
David L. Olds,
Joanna D. Holbrook,
Michael S. Kobor,
Michael J. Meaney
Translational Psychiatry
5 Dec 2017
BMRC
Singapore Institute for Clinical Sciences
Choice of surrogate tissue influences neonatal EWAS findings
Xinyi Lin,
Ai Ling Teh,
Li Chen,
Ives Yubin Lim,
Pei Fang Tan,
Julia L. MacIsaac,
Alexander M. Morin,
Fabian Yap,
Kok Hian Tan,
Seang Mei Saw,
Yung Seng Lee,
Joanna D. Holbrook,
Keith M. Godfrey,
Michael J. Meaney,
Michael S. Kobor,
Yap Seng Chong,
Peter D. Gluckman,
Neerja Karnani
BMC Medicine
26 Apr 2017
BMRC
Singapore Institute for Clinical Sciences
ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity
Karen Lillycrop,
Robert Murray,
Clara Cheong,
Ai Ling Teh,
Rebecca Clarke-Harris,
Sheila Barton,
Paula Costello,
Emma Garratt,
Eloise Cook,
Philip Titcombe,
Bhuvaneshwari Shunmuganathan,
Carolina Paras Chavez,
Philip C. Calder,
Fabian Yap,
Yung Seng Lee,
Yap Seng Chong,
Philip E. Melton,
Lawrie Beilin,
Rae-Chi Huang,
Samantha J. Liew,
Yong-Cai Chua,
Xinyi Lin,
Yonghui Wu,
Graham C. Burdge,
Cyrus Cooper,
Hazel M. Inskip,
Neerja Karnani,
James C. Hopkins,
Caroline E. Childs,
Peter D. Gluckman,
Nick Harvey,
Mark A. Hanson,
Joanna D. Holbrook,
EpiGen Consortium,
Keith M. Godfrey
EBioMedicine
7 Mar 2017
BMRC
Singapore Institute for Clinical Sciences
Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome
Xinyi Lin,
Ives Yubin Lim,
Yonghui Wu,
Ai Ling Teh,
Li Chen,
Izzuddin M. Aris,
Shu E Soh,
Mya Thway Tint,
Julia L. MacIsaac,
Alexander M. Morin,
Fabian Yap,
Kok Hian Tan,
Seang Mei Saw,
Michael S. Kobor,
Michael J. Meaney,
Keith M. Godfrey,
Yap Seng Chong,
Joanna D. Holbrook,
Yung Seng Lee,
Peter D. Gluckman,
Neerja Karnani,
GUSTO Study Group
BMC Medicine
2 Aug 2016
BMRC
Singapore Institute for Clinical Sciences
Gene, Environment and Methylation (GEM): a tool suite to efficiently navigate large scale epigenome wide association studies and integrate genotype and interaction between genotype and environment
Hong Pan,
Joanna D. Holbrook,
Neerja Karnani,
Chee Keong Kwoh
BMC Bioinformatics
22 Feb 2016
BMRC
Singapore Institute for Clinical Sciences
Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples
Ai Ling Teh,
Hong Pan,
Xinyi Lin,
Yubin Ives Lim,
Chinari Pawan Kumar Pantro,
Clara Yujing Cheong,
Min Gong,
Julia L. MacIsaac,
Chee-Keong Kwoh,
Michael J. Meaney,
Michael S. Kobor,
Yap-Seng Chong,
Peter D. Gluckman,
Joanna D. Holbrook,
Neerja Karnani
Epigenetics
1 Oct 2015
BMRC
Singapore Institute for Clinical Sciences
Ethnic differences in effects of maternal pre-pregnancy and pregnancy adiposity on offspring size and adiposity
Izzuddin M. Aris,
Xinyi Lin,
Mya Thway Tint,
Shu E Soh,
Keith M. Godfrey,
George Seow-Heong Yeo,
Kenneth Kwek,
Jerry Kok-Yen Chan,
Peter D. Gluckman,
Yap Seng Chong,
Fabian Yap,
Joanna D. Holbrook,
Yung Seng Lee
The Journal of Clinical Endocrinology & Metabolism
20 Aug 2015
BMRC
Singapore Institute for Clinical Sciences
Rate of establishing the gut microbiota in infancy has consequences for future health
Shaillay Dogra,
Olga Sakwinska,
Shu-E Soh,
Catherine Ngom-Bru,
Wolfram M. Brück,
Bernard Berger,
Harald Brüssow,
Neerja Karnani,
Yung Seng Lee,
Fabian Yap,
Yap-Seng Chong,
Keith M. Godfrey,
Joanna D. Holbrook
Gut Microbes
26 May 2015
BMRC
Singapore Institute for Clinical Sciences
HIF3A association with adiposity: the story begins before birth
Hong Pan,
Xinyi Lin,
Yonghui Wu,
Li Chen,
Ai Ling Teh,
Shu E Soh,
Yung Seng Lee,
Michael J. Meaney,
Keith M. Godfrey,
Mya Thway Tint,
Julia L. MacIsaac,
Alexander M. Morin,
Kok Hian Tan,
Fabian Yap,
Seang Mei Saw,
Michael S. Kobor,
Yap-Seng Chong,
Peter D. Gluckman,
Neerja Karnani,
Joanna D. Holbrook,
GUSTO Study Group
Epigenomics
2 Oct 2014
BMRC
Singapore Institute for Clinical Sciences
Ethnic differences translate to inadequacy of high-risk screening for gestational diabetes mellitus in an Asian population: a cohort study
Yap-Seng Chong,
Shirong Cai,
Harvard Lin,
Shu E Soh,
Yung-Seng Lee,
Melvin Khee-Shing Leow,
Yiong-Huak Chan,
Li Chen,
Joanna D. Holbrook,
Kok-Hian Tan,
Victor Samuel Rajadurai,
George Seow-Heong Yeo,
Michael S. Kramer,
Seang-Mei Saw,
Peter D. Gluckman,
Keith M. Godfrey,
Kenneth Kwek
BMC Pregnancy Childbirth
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