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19 Jan 2023
BMRC
Bioinformatics Institute
The Singapore National Precision Medicine Strategy
Eleanor Wong,
Nicolas Bertin,
Maxime Hebrard,
Roberto Tirado-Magallanes,
Claire Bellis,
Weng Khong Lim,
Chee Yong Chua,
Philomena Mei Lin Tong,
Raymond Chua,
Kenneth Mak,
Tit Meng Lim,
Wei Yang Cheong,
Kwee Eng Thien,
Khean Teik Goh,
Jin-Fang Chai,
Jimmy Lee,
Joseph Jao-Yiu Sung,
Tien Yin Wong,
Calvin Woon Loong Chin,
Peter D. Gluckman,
Liuh Ling Goh,
Kenneth Hon Kim Ban,
Tin Wee Tan,
,
Rob M. van Dam,
Yik Ying Teo,
Marie Loh,
Paul Eillot,
Eng Sing Lee,
Joanne Ngeow,
Elio Riboli,
Rinkoo Dalan,
Irfahan Kassam,
Lakshmi Narayanan Lakshmanan,
Tock Han Lim,
Hong Kiat Ng,
Theresia Mina,
Darwin Tay,
Charumathi Sabanayagam,
Yih Chung Tham,
Tyler Rim,
Tin Aung,
Miao Ling Chee,
Hengtong Li,
Miao Li Chee,
Khung Keong Yeo,
Stuart Alexander Cook,
Chee Jian Pua,
Chengxi Yang,
Yap Seng Chong,
Johan Gunnar Eriksson,
Kok Hian Tan,
Fabian Yap,
Chia Wei Lim,
Pi Kuang Tsai,
Wen Jie Chew,
Wey Ching Sim,
Li-xian Grace Toh,
Clarabelle Bitong Lin,
Yee Yen Sia,
Tat Hung Koh,
Wee Yang Meah,
Joanna Hui Juan Tan,
Justin Jeyakani,
Jack Ow,
Shimin Ang,
Ashar J. Malik,
Dimitar Kenanov,
Xueling Sim,
Ching-Yu Cheng,
Sonia Davila,
Neerja Karnani,
Khai Pang Leong,
Jianjun Liu,
Shyam Prabhakar,
Sebastian Maurer-Stroh,
Chandra Shekhar Verma,
Pavitra Krishnaswamy,
Rick Siow Mong Goh,
Irenaeus Chia,
Clarissa Ho,
Doreen Low,
Suchin Virabhak,
Jacklyn Yong,
Weiling Zheng,
Shih Wee Seow,
Yee Kwang Seck,
Mingshi Koh,
John C. Chambers,
E. Shyong Tai,
Patrick Tan
Nature Genetics
17 Oct 2019
BMRC
Genome Institute of Singapore
Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore
Degang Wu,
Jinzhuang Dou,
Xiaoran Chai,
Claire Bellis,
Andreas Wilm,
Chih Chuan Shih,
Wendy Wei Jia Soon,
Nicolas Bertin,
Clarabelle Bitong Lin,
Chiea Chuen Khor,
Michael DeGiorgio,
Shanshan Cheng,
Li Bao,
Neerja Karnani,
William Ying Khee Hwang,
Sonia Davila,
Patrick Tan,
Asim Shabbir,
Angela Moh,
Eng-King Tan,
Jia Nee Foo,
Luih Ling Goh,
Khai Pang Leong,
Roger S. Y. Foo,
Carolyn Su Ping Lam,
Arthur Mark Richards,
Ching-Yu Cheng,
Tin Aung,
Tien Yin Wong,
Huck Hui Ng,
Jianjun Liu,
Chaolong Wang
Cell
30 May 2018
BMRC
Bioinformatics Institute
Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes
Manuela Pigors,
John E. A. Common,
Xuan Fei Colin C. Wong,
Sajid Malik,
Claire A. Scott,
Niloofar Tabarra,
Herty Liany,
Jianjun Liu,
Vachiranee Limviphuvadh,
Sebastian Maurer-Stroh,
Mark B. Y. Tang,
Nicholas Lench,
David J. Margolis,
David A. van Heel,
Charles A. Mein,
Natalija Novak,
Hansjorg Baurecht,
Stephan Weidinger,
Erwin W. H. McLean,
Alan D. Irvine,
Edel A. O'Toole,
Michael A. Simpson,
David P. Kelsell
Journal of Investigative Dermatology
30 May 2018
BMRC
Bioinformatics Institute
Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes
Manuela Pigors,
John E. A. Common,
Xuan Fei Colin C. Wong,
Sajid Malik,
Claire A. Scott,
Niloofar Tabarra,
Herty Liany,
Jianjun Liu,
Vachiranee Limviphuvadh,
Nicholas Lench,
Sebastian Maurer-Stroh,
Mark B. Y. Tang,
David J. Margolis,
David A. van Heel,
Charles A. Mein,
Natalija Novak,
Hansjorg Baurecht,
Stephan Weidinger,
W. H. Irwin McLean,
Alan D. Irvine,
Edel A. O'Toole,
Michael A. Simpson,
David P. Kelsell
Journal of Investigative Dermatology
19 Oct 2017
BMRC
Skin Research Lab
Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants
(Pending publish)
X.F. Colin C. Wong,
Simon L.I.J. Denil,
Jia Nee Foo,
Huijia Chen,
Angeline Su Ling Tay,
Rebecca L. Haines,
Mark B.Y. Tang,
W.H. Irwin McLean,
Aileen Sandilands,
Frances J.D. Smith,
E. Birgitte Lane,
Jianjun Liu,
John E.A. Common
Journal of Allergy and Clinical Immunology
28 Sep 2017
BMRC
Skin Research Lab
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis
Marwa Chourabi,
Mei Shan Liew,
Shawn Lim,
Dorra H’mida-Ben Brahim,
Lobna Boussofara,
Liang Dai,
Pui Mun Wong,
Jia Nee Foo,
Badreddine Sriha,
Kim Samirah Robinson,
Simon Denil,
John EA Common,
Ons Mamai,
Youcef Ben Khalifa,
Mathieu Bollen,
Jianjun Liu,
Mohamed Denguezli,
Carine Bonnard,
Ali Saad,
Bruno Reversade
Journal of Investigative Dermatology
2 Feb 2015
BMRC
Genome Institute of Singapore
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy
Hong Liu,
Astrid Irwanto,
Xi'an Fu,
Gongqi Yu,
Yongxiang Yu,
Yonghu Sun,
Chuan Wang,
Zhenzhen Wang,
Yukinori Okada,
Huiqi Low,
Yi Li,
Herty Liany,
Mingfei Chen,
Fangfang Bao,
Jinghui Li,
Jiabao You,
Qilin Zhang,
Jian Liu,
Tongsheng Chu,
Anand Kumar Andiappan,
Na Wang,
Guiye Niu,
Dianchang Liu,
Xiulu Yu,
Lin Zhang,
Hongqing Tian,
Guizhi Zhou,
Olaf Rotzschke,
Shumin Chen,
Xuejun Zhang,
Jianjun Liu,
Furen Zhang
Nature Genetics
30 Jan 2015
BMRC
Institute of Molecular and Cell Biology
Elevation of a Novel Angiogenic Factor, Leucine-Rich-α2-Glycoprotein (LRG1), Is Associated With Arterial Stiffness, Endothelial Dysfunction, and Peripheral Arterial Disease in Patients With Type 2 Diabetes
Sharon L. T. Pek,
S. Tavintharan,
Xiaomeng Wang,
Su Chi Lim,
Kaing Woon,
Lee Ying Yeoh,
Xiaowei Ng,
Jianjun Liu,
Chee Fang Sum
The Journal of Clinical Endocrinology & Metabolism
7 Aug 2014
BMRC
Institute of Molecular and Cell Biology
Genetic variants of inducible costimulator are associated with allergic asthma susceptibility
Rachel A. Myers,
Bernett Lee,
Maartje A. Nieuwenhuis,
Alessandra Nardin,
Choon-Sik Park,
Hyoung Doo Shin,
Jeong-Hyun Kim,
Anand Kumar Andiappan,
Sriram Narayanan,
Harm-Jan Westra,
Lude Franke,
Tonu Esko,
Andres Metspalu,
Yik-Ying Teo,
Seang Mei Saw,
Chiea Chuen Khor,
Jianjun Liu,
Gerard H. Koppelman,
Dirkje S. Postma,
Michael Poidinger,
John E. Connolly,
De Yun Wang,
Olaf Rotzschke,
Maria A. Curotto de Lafaille,
Fook Tim Chew
Journal of Allergy and Clinical Immunology
17 Jun 2014
BMRC
Genome Institute of Singapore
2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
Dieter Flesch-Janys,
Petra Seibold,
Anja Rudolph,
Graham G. Giles,
Laura Baglietto,
Gianluca Severi,
Christopher A. Haiman,
Brian E. Henderson,
Fredrick Schumacher,
Loic Le Marchand,
Vessela Kristensen,
Grethe I. Grenaker Alnæs,
Anne-Lise Borresen-Dale,
Silje Nord,
Robert Winqvist,
Yi Li,
Ute Hamann,
Diana Torres,
Hans U. Ulmer,
Thomas Rüdiger,
Chen-Yang Shen,
Chia-Ni Hsiung,
Katri Pylkäs,
Arja Jukkola-Vuorinen,
Mervi Grip,
Irene L. Andrulis,
Julia A. Knight,
Gord Glendon,
Sandrine Tchatchou,
Peter Devilee,
Robert Tollenaar,
Caroline Seynaeve,
Maartje Hooning,
Mieke Kriege,
Antoinette Hollestelle,
Ans van den Ouweland,
Nur Aishah Mohd Taib,
Pei-Ei Wu,
Shou-Tung Chen,
Soo Hwang Teo,
Cheng Har Yip,
Gwo Fuang Ho,
Keitaro Matsuo,
Hidemi Ito,
Hiroji Iwata,
Kazuo Tajima,
Daehee Kang,
Ji-Yeob Choi,
Sue K. Park,
Keun-Young Yoo,
Tom Maishman,
William J. Tapper,
Alison Dunning,
Mitul Shah,
Robert Luben,
Judith Brown,
Chiea Chuen Khor,
Diana M. Eccles,
Heli Nevanlinna,
Douglas Easton,
Keith Humphreys,
Jianjun Liu,
Per Hall,
Kamila Czene,
Sara Margolin,
Arto Mannermaa,
Veli-Matti Kosma,
Jaana M. Hartikainen,
Vesa Kataja,
Georgia Chenevix-Trench,
kConFab Investigators,
Kelly-Anne Phillips,
Laura J. Van ‘t Veer,
Sten Cornelissen,
Emiel Rutgers,
Jingmei Li,
Linda S. Lindström,
Jia N. Foo,
Sajjad Rafiq,
Melissa C. Southey,
Carmel Apicella,
Gillian S. Dite,
John L. Hopper,
Peter A. Fasching,
Lothar Haeberle,
Arif B. Ekici,
Matthias W. Beckmann,
Carl Blomqvist,
Taru A. Muranen,
Kristiina Aittomaki,
Annika Lindblom,
Marjanka K. Schmidt,
Paul D. P. Pharoah,
Kyriaki Michailidou,
Joe Dennis,
Manjeet K. Bolla,
Qin Wang,
Sue-Anne McLachlan,
Diether Lambrechts,
Bernard Thienpont,
Ann Smeets,
Hans Wildiers,
Jenny Chang-Claude
Nature Communications
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