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17 Oct 2019 BMRC Genome Institute of Singapore Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore Degang Wu, Jinzhuang Dou, Xiaoran Chai, Claire Bellis, Andreas Wilm, Chih Chuan Shih, Wendy Wei Jia Soon, Nicolas Bertin, Clarabelle Bitong Lin, Chiea Chuen Khor, Michael DeGiorgio, Shanshan Cheng, Li Bao, Neerja Karnani, William Ying Khee Hwang, Sonia Davila, Patrick Tan, Asim Shabbir, Angela Moh, Eng-King Tan, Jia Nee Foo, Luih Ling Goh, Khai Pang Leong, Roger S. Y. Foo, Carolyn Su Ping Lam, Arthur Mark Richards, Ching-Yu Cheng, Tin Aung, Tien Yin Wong, Huck Hui Ng, Jianjun Liu, Chaolong Wang
30 May 2018 BMRC Bioinformatics Institute Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes Manuela Pigors, John E. A. Common, Xuan Fei Colin C. Wong, Sajid Malik, Claire A. Scott, Niloofar Tabarra, Herty Liany, Jianjun Liu, Vachiranee Limviphuvadh, Nicholas Lench, Sebastian Maurer-Stroh, Mark B. Y. Tang, David J. Margolis, David A. van Heel, Charles A. Mein, Natalija Novak, Hansjorg Baurecht, Stephan Weidinger, W. H. Irwin McLean, Alan D. Irvine, Edel A. O'Toole, Michael A. Simpson, David P. Kelsell
30 May 2018 BMRC Bioinformatics Institute Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes Manuela Pigors, John E. A. Common, Xuan Fei Colin C. Wong, Sajid Malik, Claire A. Scott, Niloofar Tabarra, Herty Liany, Jianjun Liu, Vachiranee Limviphuvadh, Sebastian Maurer-Stroh, Mark B. Y. Tang, Nicholas Lench, David J. Margolis, David A. van Heel, Charles A. Mein, Natalija Novak, Hansjorg Baurecht, Stephan Weidinger, Erwin W. H. McLean, Alan D. Irvine, Edel A. O'Toole, Michael A. Simpson, David P. Kelsell
2 Feb 2015 BMRC Genome Institute of Singapore Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy Hong Liu, Astrid Irwanto, Xi'an Fu, Gongqi Yu, Yongxiang Yu, Yonghu Sun, Chuan Wang, Zhenzhen Wang, Yukinori Okada, Huiqi Low, Yi Li, Herty Liany, Mingfei Chen, Fangfang Bao, Jinghui Li, Jiabao You, Qilin Zhang, Jian Liu, Tongsheng Chu, Anand Kumar Andiappan, Na Wang, Guiye Niu, Dianchang Liu, Xiulu Yu, Lin Zhang, Hongqing Tian, Guizhi Zhou, Olaf Rotzschke, Shumin Chen, Xuejun Zhang, Jianjun Liu, Furen Zhang
30 Jan 2015 BMRC Institute of Molecular and Cell Biology Elevation of a Novel Angiogenic Factor, Leucine-Rich-α2-Glycoprotein (LRG1), Is Associated With Arterial Stiffness, Endothelial Dysfunction, and Peripheral Arterial Disease in Patients With Type 2 Diabetes Sharon L. T. Pek, S. Tavintharan, Xiaomeng Wang, Su Chi Lim, Kaing Woon, Lee Ying Yeoh, Xiaowei Ng, Jianjun Liu, Chee Fang Sum
7 Aug 2014 BMRC Institute of Molecular and Cell Biology Genetic variants of inducible costimulator are associated with allergic asthma susceptibility Rachel A. Myers, Bernett Lee, Maartje A. Nieuwenhuis, Alessandra Nardin, Choon-Sik Park, Hyoung Doo Shin, Jeong-Hyun Kim, Anand Kumar Andiappan, Sriram Narayanan, Harm-Jan Westra, Lude Franke, Tonu Esko, Andres Metspalu, Yik-Ying Teo, Seang Mei Saw, Chiea Chuen Khor, Jianjun Liu, Gerard H. Koppelman, Dirkje S. Postma, Michael Poidinger, John E. Connolly, De Yun Wang, Olaf Rotzschke, Maria A. Curotto de Lafaille, Fook Tim Chew
17 Jun 2014 BMRC Genome Institute of Singapore 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy Dieter Flesch-Janys, Petra Seibold, Anja Rudolph, Graham G. Giles, Laura Baglietto, Gianluca Severi, Christopher A. Haiman, Brian E. Henderson, Fredrick Schumacher, Loic Le Marchand, Vessela Kristensen, Grethe I. Grenaker Alnæs, Anne-Lise Borresen-Dale, Silje Nord, Robert Winqvist, Yi Li, Ute Hamann, Diana Torres, Hans U. Ulmer, Thomas Rüdiger, Chen-Yang Shen, Chia-Ni Hsiung, Katri Pylkäs, Arja Jukkola-Vuorinen, Mervi Grip, Irene L. Andrulis, Julia A. Knight, Gord Glendon, Sandrine Tchatchou, Peter Devilee, Robert Tollenaar, Caroline Seynaeve, Maartje Hooning, Mieke Kriege, Antoinette Hollestelle, Ans van den Ouweland, Nur Aishah Mohd Taib, Pei-Ei Wu, Shou-Tung Chen, Soo Hwang Teo, Cheng Har Yip, Gwo Fuang Ho, Keitaro Matsuo, Hidemi Ito, Hiroji Iwata, Kazuo Tajima, Daehee Kang, Ji-Yeob Choi, Sue K. Park, Keun-Young Yoo, Tom Maishman, William J. Tapper, Alison Dunning, Mitul Shah, Robert Luben, Judith Brown, Chiea Chuen Khor, Diana M. Eccles, Heli Nevanlinna, Douglas Easton, Keith Humphreys, Jianjun Liu, Per Hall, Kamila Czene, Sara Margolin, Arto Mannermaa, Veli-Matti Kosma, Jaana M. Hartikainen, Vesa Kataja, Georgia Chenevix-Trench, kConFab Investigators, Kelly-Anne Phillips, Laura J. Van ‘t Veer, Sten Cornelissen, Emiel Rutgers, Jingmei Li, Linda S. Lindström, Jia N. Foo, Sajjad Rafiq, Melissa C. Southey, Carmel Apicella, Gillian S. Dite, John L. Hopper, Peter A. Fasching, Lothar Haeberle, Arif B. Ekici, Matthias W. Beckmann, Carl Blomqvist, Taru A. Muranen, Kristiina Aittomaki, Annika Lindblom, Marjanka K. Schmidt, Paul D. P. Pharoah, Kyriaki Michailidou, Joe Dennis, Manjeet K. Bolla, Qin Wang, Sue-Anne McLachlan, Diether Lambrechts, Bernard Thienpont, Ann Smeets, Hans Wildiers, Jenny Chang-Claude
1 Apr 2014 BMRC Genome Institute of Singapore DNAJ mutations are rare in Chinese Parkinson's disease patients and controls Eng-King Tan, Jia Nee Foo, Herty Liany, Louis C. Tan, Wing-Lok Au, Kumar-M. Prakash, Jianjun Liu
10 Feb 2014 BMRC Genome Institute of Singapore Joint Effects of Known Type 2 Diabetes Susceptibility Loci in Genome-Wide Association Study of Singapore Chinese: The Singapore Chinese Health Study Zhanghua Chen, Mark A. Pereira, Mark Seielstad, Woon-Puay Koh, E. Shyong Tai, Yik-Ying Teo, Jianjun Liu, Chris Hsu, Renwei Wang, Andrew O. Odegaard, Bharat Thyagarajan, Revati Koratkar, Jian-Min Yuan, Myron D. Gross, Daniel O. Stram, Qingyang Huang
3 Feb 2014 BMRC Genome Institute of Singapore Genome-Wide Linkage, Exome Sequencing and Functional Analyses Identify ABCB6 as the Pathogenic Gene of Dyschromatosis Universalis Hereditaria Na Wang, Hong Liu, Yi Li, Ken Kwok Hon Hung, Chuan Wang, Xuechao Chen, Donglai Sheng, Xi’an Fu, Kelvin See, Jia Nee Foo, Huiqi Low, Herty Liany, Ishak Darryl Irwan, Jian Liu, Baoqi Yang, Mingfei Chen, Yongxiang Yu, Gongqi Yu, Boon Kee Goh, John E. A. Common, Guiye Niu, Jiabao You, Yan Zhou, Shanshan Ma, Ting Wang, Xiaoxiao Yan, Birgitte E. Lane, Yonghu Sun, Guizhi Zhou, Xianmei Lu, Zhenhua Wang, Hongqing Tian, Yuanhua Cao, Shumin Chen, Qiji Liu, Jianjun Liu, Furen Zhang, Mathias Toft
3 Feb 2014 BMRC Institute of Medical Biology Genome-wide linkage, exome sequencing and functional analyses identify ABCB6 as the pathogenic gene of dyschromatosis universalis hereditaria Herty Liany, Ishak Darryl Irwan, Jian Liu, Hong Liu, Yi Li, Ken Kwok Hon Hung, Na Wang, Chuan Wang, Xuechao Chen, Donglai Sheng, Xi'an Fu, Kelvin See, Jia Nee Foo, Huiqi Low, Baoqi Yang, Mingfei Chen, Yongxiang Yu, Gongqi Yu, Guiye Niu, Jiabao You, Yan Zhou, Shanshan Ma, Ting Wang, Xiaoxiao Yan, Boon Kee Goh, John E. A. Common, Birgitte E. Lane, Yonghu Sun, Guizhi Zhou, Xianmei Lu, Zhenhua Wang, Hongqing Tian, Yuanhua Cao, Shumin Chen, Qiji Liu, Jianjun Liu, Furen Zhang
5 Dec 2013 BMRC Genome Institute of Singapore Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1 Kerstin B. Meyer, Martin O’Reilly, Kyriaki Michailidou, Saskia Carlebur, Stacey L. Edwards, Juliet D. French, Radhika Prathalingham, Joe Dennis, Andreas Schneeweiss, Manjeet K. Bolla, Qin Wang, Ines de Santiago, John L. Hopper, Helen Tsimiklis, Carmel Apicella, Melissa C. Southey, Marjanka K. Schmidt, Annegien Broeks, Laura J. Van ’t Veer, Frans B. Hogervorst, Kenneth Muir, Artitaya Lophatananon, Sarah Stewart-Brown, Pornthep Siriwanarangsan, Peter A. Fasching, Michael P. Lux, Arif B. Ekici, Matthias W. Beckmann, Julian Peto, Isabel dos Santos Silva, Olivia Fletcher, Nichola Johnson, Elinor J. Sawyer, Ian Tomlinson, Michael J. Kerin, Nicola Miller, Federick Marme, Christof Sohn, Barbara Burwinkel, Pascal Guénel, Thérèse Truong, Pierre Laurent-Puig, Florence Menegaux, Stig E. Bojesen, Børge G. Nordestgaard, Sune F. Nielsen, Henrik Flyger, Roger L. Milne, M. Pilar Zamora, Jose I. Arias, Javier Benitez, Susan Neuhausen, Hoda Anton-Culver, Argyrios Ziogas, Christina C. Dur, Hermann Brenner, Heiko Müller, Volker Arndt, Christa Stegmaier, Alfons Meindl, Rita K. Schmutzler, Christoph Engel, Nina Ditsch, Hiltrud Brauch, Thomas Brüning, Yon-Dschun Ko, Heli Nevanlinna, Taru A. Muranen, Kristiina Aittomaki, Carl Blomqvist, Keitaro Matsuo, Hidemi Ito, Hiroji Iwata, Yasushi Yatabe, Thilo Dörk, Sonja Helbig, Natalia V. Bogdanova, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana M. Hartikainen, Georgia Chenevix-Trench, Anna H. Wu, Chiu-chen Tseng, David Van Den Berg, Daniel O. Stram, Diether Lambrechts, Bernard Thienpont, Marie-Rose Christiaens, Ann Smeets, Petra Seibold, Dieter Flesch-Janys, Paolo Radice, Paolo Peterlongo, Bernardo Bonanni, Jenny Chang-Claude, Anja Rudolph, Loris Bernard, Fergus J. Couch, Janet E. Olson, Xianshu Wang, Kristen Purrington, Graham G. Giles, Gianluca Severi, Laura Baglietto, Catriona McLean, Christopher A. Haiman, Brian E. Henderson, Fredrick Schumacher, Loic Le Marchand, Jacques Simard, Mark S. Goldberg, France Labrèche, Martine Dumont, Soo-Hwang Teo, Cheng-Har Yip, Sze-Yee Phuah, Vessela Kristensen, Grethe Grenaker Alnæs, Anne-Lise Børresen-Dale, Wei Zheng, Sandra Deming-Halverson, Martha Shrubsole, Jirong Long, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Saila Kauppila, Irene L. Andrulis, Julia A. Knight, Gord Glendon, Sandrine Tchatchou, Peter Devilee, Robert A.E.M. Tollenaar, Caroline M. Seynaeve, Montserrat García-Closas, Jonine Figueroa, Stephen J. Chanock, Jolanta Lissowska, Kamila Czene, Hartef Darabi, Kimael Eriksson, Maartje J. Hooning, John W.M. Martens, Ans M.W. van den Ouweland, Carolien H.M. van Deurzen, Per Hall, Jingmei Li, Jianjun Liu, Keith Humphreys, Hui Cai, Angela Cox, Malcolm W.R. Reed, Xiao-ou Shu, William Blot, Lisa B. Signorello, Qiuyin Cai, Wei Lu, Yu-Tang Gao, Paul D.P. Pharoah, Jonathan Tyrer, Maya Ghoussaini, Patricia Harrington, Daehee Kang, Ji-Yeob Choi, Sue K. Park, Dong-Young Noh, Mikael Hartman, Miao Hui, Wei-Yen Lim, Shaik A. Buhari, Ute Hamann, Asta Försti, Thomas Rüdiger, Hans-Ulrich Ulmer, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Suleeporn Sangrajrang, Valerie Gaborieau, Paul Brennan, James McKay, Celine Vachon, Susan Slager, Florentia Fostira, Robert Pilarski, Chen-Yang Shen, Chia-Ni Hsiung, Pei-Ei Wu, Ming-Feng Hou, Anthony Swerdlow, Alan Ashworth, Nick Orr, Minouk J. Schoemaker, Bruce A.J. Ponder, Alison M. Dunning, Douglas F. Easton
1 Dec 2013 BMRC Genome Institute of Singapore A rare lysosomal enzyme gene SMPD1 variant (p.R591C) associates with Parkinson's disease Jia-Nee Foo, Herty Liany, Jin-Xin Bei, Xue-Qing Yu, Kumar M. Prakash, Louis C. Tan, Eng-King Tan, Jianjun Liu, Wing-Lok Au
22 Nov 2013 BMRC Genome Institute of Singapore An Evaluation of Association between a Novel Hippocampal Biology Related SNP (rs7294919) and Schizophrenia Siow-Ann Chong, Jiewei Liu, Shusuke Numata, Masashi Ikeda, Yuichiro Watanabe, Xue-bin Zheng, Xiongjian Luo, Makoto Kinoshita, Ayako Nunokawa, Toshiyuki Someya, Tetsuro Ohmori, Jin-Xin Bei, Jimmy Lee, Zhiqiang Li, Jianjun Liu, Nakao Iwata, Yongyong Shi, Ming Li, Bing Su, Chunyu Liu
7 Nov 2013 BMRC Genome Institute of Singapore A Study Assessing the Association of Glycated Hemoglobin A1C (HbA1C) Associated Variants with HbA1C, Chronic Kidney Disease and Diabetic Retinopathy in Populations of Asian Ancestry Peng Chen, Rick Twee-Hee Ong, Wan-Ting Tay, Xueling Sim, Mohammad Ali, Haiyan Xu, Chen Suo, Jianjun Liu, Kee-Seng Chia, Eranga Vithana, Terri L. Young, Tin Aung, Wei-Yen Lim, Chiea-Chuen Khor, Ching-Yu Cheng, Tien-Yin Wong, Yik-Ying Teo, E-Shyong Tai, Mingguang He
20 Jun 2013 BMRC Genome Institute of Singapore Coding Variants at Hexa-allelic Amino Acid 13 of HLA-DRB1 Explain Independent SNP Associations with Follicular Lymphoma Risk Mads Melbye, Jia Nee Foo, Karin E. Smedby, Nicholas K. Akers, Mattias Berglund, Ishak D. Irwan, Xiaoming Jia, Yi Li, Lucia Conde, Hatef Darabi, Paige M. Bracci, Hans-Olov Adami, Bengt Glimelius, Chiea Chuen Khor, Henrik Hjalgrim, Leonid Padyukov, Keith Humphreys, Gunilla Enblad, Christine F. Skibola, Paul I.W. de Bakker, Jianjun Liu
14 May 2011 BMRC Genome Institute of Singapore Coffee consumption modifies risk of estrogen-receptor negative breast cancer Jingmei Li, Petra Seibold, Jenny Chang-Claude, Dieter Flesch-Janys, Jianjun Liu, Kamila Czene, Keith Humphreys, Per Hall
21 Apr 2011 BMRC Genome Institute of Singapore GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma Stephen J. Chanock, Mark P. Purdue, Claire M. Vajdic, Peter Boyle, Karin E. Smedby, Jia Nee Foo, Christine F. Skibola, Hatef Darabi, Lucia Conde, Henrik Hjalgrim, Vikrant Kumar, Ellen T. Chang, Nathaniel Rothman, James R. Cerhan, Angela R. Brooks-Wilson, Emil Rehnberg, Ishak D. Irwan, Lars P. Ryder, Peter N. Brown, Paige M. Bracci, Luz Agana, Jacques Riby, Wendy Cozen, Scott Davis, Patricia Hartge, Lindsay M. Morton, Richard K. Severson, Sophia S. Wang, Susan L. Slager, Zachary S. Fredericksen, Anne J. Novak, Neil E. Kay, Thomas M. Habermann, Bruce Armstrong, Anne Kricker, Sam Milliken, Qing Lan, Shelia H. Zahm, Yawei Zhang, Tongzhang Zheng, Stephen Leach, John J. Spinelli, Martyn T. Smith, Leonid Padyukov, Lars Alfredsson, Lars Klareskog, Bengt Glimelius, Mads Melbye, Edison T. Liu, Hans-Olov Adami, Keith Humphreys, Jianjun Liu, Greg Gibson
26 Jan 2011 BMRC Genome Institute of Singapore Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer Sara Wedrén, Guoliang Li, Yuqing Li, Yi Li, Tze Howe Charn, Kartiki Vasant Desai, Carine Bonnard, Kamila Czene, Keith Humphreys, Hatef Darabi, Kristjana Einarsdóttir, Tuomas Heikkinen, Kristiina Aittomaki, Carl Blomqvist, Kee Seng Chia, Heli Nevanlinna, Per Hall, Edison T Liu, Jianjun Liu
12 Jan 2011 BMRC Genome Institute of Singapore Pathway-based analysis using reduced gene subsets in genome-wide association studies Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianjun Liu, Anbupalam Thalamuthu
9 Nov 2010 BMRC Genome Institute of Singapore A genome-wide association scan on estrogen receptor -negative breast cancer Jingmei Li, Keith Humphreys, Hatef Darabi, Gustaf Rosin, Ulf Hannelius, Tuomas Heikkinen, Kristiina Aittomaki, Carl Blomqvist, Paul DP Pharoah, Alison M Dunning, Shahana Ahmed, Maartje J Hooning, Antoinette Hollestelle, Rogier A Oldenburg, Lars Alfredsson, Aarno Palotie, Leena Peltonen-Palotie, Astrid Irwanto, Hui Qi Low, Garrett HK Teoh, Anbupalam Thalamuthu, Juha Kere, Mauro D'Amato, Douglas F Easton, Heli Nevanlinna, Jianjun Liu, Kamila Czene, Per Hall
1 Jul 2010 BMRC Genome Institute of Singapore Multi-Variant Pathway Association Analysis Reveals the Importance of Genetic Determinants of Estrogen Metabolism in Breast and Endometrial Cancer Susceptibility Yen Ling Low, Yuqing Li, Keith Humphreys, Anbupalam Thalamuthu, Yi Li, Hatef Darabi, Sara Wedrén, Carine Bonnard, Kamila Czene, Mark M. Iles, Tuomas Heikkinen, Kristiina Aittomaki, Carl Blomqvist, Heli Nevanlinna, Per Hall, Edison T. Liu, Jianjun Liu, Kathleen Kerr
22 Apr 2010 BMRC Genome Institute of Singapore Deletion of the WD40 Domain of LRRK2 in Zebrafish Causes Parkinsonism-Like Loss of Neurons and Locomotive Defect Donglai Sheng, Dianbo Qu, Ken Hon Hung Kwok, Seok Shin Ng, Adrian Yin Ming Lim, Sharon Siqi Aw, Charlie Wah Heng Lee, Wing Kin Sung, Eng King Tan, Thomas Lufkin, Suresh Jesuthasan, Mathavan Sinnakaruppan, Jianjun Liu, Nicholas Katsanis
15 Apr 2010 BMRC Genome Institute of Singapore Effects of childhood body size on breast cancer tumour characteristics Jingmei Li, Keith Humphreys, Louise Eriksson, Kamila Czene, Jianjun Liu, Per Hall
9 Mar 2010 BMRC Genome Institute of Singapore Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer Celine M Vachon, Fergus J Couch, Christopher G Scott, Pagona Lagiou, Per Hall, Jingmei Li, Louise Eriksson, Keith Humphreys, Kamila Czene, Jianjun Liu, Rulla M Tamimi, Sara Lindström, David J Hunter
11 Dec 2009 BMRC Genome Institute of Singapore Genetic Structure of the Han Chinese Population Revealed by Genome-wide SNP Variation Houfeng Zheng, Jin-Xin Bei, Liangdan Sun, Jieming Chen, Wei-Hua Jia, Tao Li, Furen Zhang, Mark Seielstad, Yi-Xin Zeng, Xuejun Zhang, Jianjun Liu