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15 Jan 2019
BMRC
Bioinformatics Institute
Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket
Mohan R. Pradhan,
Jia Wei Siau,
Srinivasaraghavan Kannan,
Minh N. Nguyen,
Zohra Ouaray,
Chee Keong Kwoh,
David P. Lane,
Farid Ghadessy,
Chandra S. Verma
Nucleic Acids Research
28 Sep 2016
BMRC
Bioinformatics Institute
Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens
Jia Wei Siau,
Cynthia R. Coffill,
Weiyun Villien Zhang,
Yaw Sing Tan,
Juliane Hundt,
David Lane,
Chandra Verma,
Farid Ghadessy
Scientific Reports
21 Jan 2016
BMRC
Bioinformatics Institute
The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans
Cynthia R. Coffill,
Alison P. Lee,
Jia Wei Siau,
Sharon M. Chee,
Thomas L. Joseph,
Yaw Sing Tan,
Arumugam Madhumalar,
Boon-Hui Tay,
Sydney Brenner,
Chandra S. Verma,
Farid J. Ghadessy,
Byrappa Venkatesh,
David P. Lane
Genes & Development
15 Dec 2015
BMRC
p53 Laboratory
Conservative site-specific and single-copy transgenesis in human LINE-1 elements
Shree Harsha Vijaya Chandra,
Harshyaa Makhija,
Sabrina Peter,
Cho Mar Myint Wai,
Jinming Li,
Jindong Zhu,
Zhonglu Ren,
Martina Stagno D'Alcontres,
Jia Wei Siau,
Sharon Chee,
Farid John Ghadessy,
Peter Dröge
Nucleic Acids Research
18 Mar 2015
BMRC
p53 Laboratory
Directed evolution of λ integrase activity and specificity by genetic derepression
Sharon Chee,
Farid J. Ghadessy,
Jia Wei Siau,
Harshyaa Makhija,
Cho Mar Myint Wai,
Shree Harsha Vijaya Chandra Chandra,
Sabrina Peter,
Peter Dröge
Protein Engineering, Design & Selection
20 Nov 2013
BMRC
Bioinformatics Institute
Inhibition of nutlin-resistant HDM2 mutants by stapled peptides
Jia Wei Siau,
Thomas Joseph,
Sharon Chee,
Ling Li,
Larisa Yurlova,
Kourosh Zolghadr,
Christopher Brown,
David P. Lane,
Chandra Verma,
Farid Ghadessy
PLoS One
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