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Publication date Communities Collections Article title Author(s) Journal/Conference
31 Dec 2024 BMRC Bioprocessing Technology Institute Quality by Design in continuous bioprocessing: Investigating the impact of critical process parameters of multi-column chromatography during steady-state and transient phases Zi Ying Zheng, Ashley GuanBang Chen, Nuruljannah Dzulkiflie, Lyn Chiin Sim, Wen Qin Tang, Jiayu Leong, Wei Xuan Ler, Dawn Leong, Jake Chng, Norhaizat Bin Abdul Manan, Ian Walsh, Say Kong Ng, Maarten Pennings, Wei Zhang Journal of Chromatography A
29 Nov 2024 BMRC Bioprocessing Technology Institute Cellulose functionalized magnetic beads for high throughput glycosylation analysis in biotherapeutic modalities Corrine Wan, Shi Jie Tay, Beiying Qiu, Sean Chia, Ian Walsh Scientific Reports
8 Nov 2024 BMRC Bioprocessing Technology Institute Genome‐Scale Modeling of CHO Cells Unravel the Critical Role of Asparagine in Cell Culture Feed Media (Pending publish) Kuin Tian Pang, Yi Fan Hong, Fumi Shozui, Shunpei Furomitsu, Matthew Myint, Ying Swan Ho, Yaron R. Silberberg, Ian Walsh, Meiyappan Lakshmanan Biotechnology Journal
18 Oct 2024 BMRC Bioprocessing Technology Institute Thermal and pH stress dictate distinct mechanisms of monoclonal antibody aggregation Kong Meng Hoi, Kuin Tian Pang, Corrine Wan, Zi Ying Zheng, Beiying Qiu, Yuansheng Yang, Zhang Wei, Ying Swan Ho, Ian Walsh, Sean Chia International Journal of Biological Macromolecules
4 Oct 2024 BMRC Bioprocessing Technology Institute Generating and characterizing a comprehensive panel of CHO cells glycosylation mutants for advancing glycobiology and biotechnology research Ryan Haryadi, Kah Fai Chan, Pao Chun Lin, Yun Lei Tan, Corrine Wan, Wahyu Shahreel, Shi Jie Tay, Terry Nguyen-Khuong, Ian Walsh, Zhiwei Song Scientific Reports
11 Jul 2024 BMRC Bioprocessing Technology Institute Biomass specific perfusion rate as a control lever for the continuous manufacturing of biosimilar monoclonal antibodies from CHO cell cultures Jiayu Leong, Wen Qin Tang, Jake Chng, Wei Xuan Ler, Norhaizat Abdul Manan, Lyn Chiin Sim, Zi Ying Zheng, Wei Zhang, Ian Walsh, Gerben Zijlstra, Maarten Pennings, Say Kong Ng Biotechnology Journal
20 Sep 2023 BMRC Bioprocessing Technology Institute Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform Ngan T. B. Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B. H. Choo, Yuansheng Yang Scientific Reports
7 Jun 2023 BMRC Bioprocessing Technology Institute Understanding and controlling the molecular mechanisms of protein aggregation in mAb therapeutics Kuin Tian Pang, Yuan Sheng Yang, Wei Zhang, Ying Swan Ho, Pietro Sormanni, Thomas C.T. Michaels, Ian Walsh, Sean Chia Biotechnology Advances
12 May 2023 BMRC Bioprocessing Technology Institute Insight into muscle stem cell regeneration and mechanobiology Kuin Tian Pang, Larry Sai Weng Loo, Sean Chia, Francesca Yi Teng Ong, Hanry Yu, Ian Walsh Stem Cell Research &Therapy
22 Apr 2023 BMRC Bioprocessing Technology Institute Enhancing pharmacokinetic and pharmacodynamic properties of recombinant therapeutic proteins by manipulation of sialic acid content Sean Chia, Shi Jie Tay, Zhiwei Song, Yuansheng Yang, Ian Walsh, Kuin Tian Pang Biomedicine & Pharmacotherapy