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21 Dec 2020
BMRC
Institute of Molecular and Cell Biology
Remodelling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division
Jin Rong Ow,
Matias J Caldez,
Gözde Zafer,
Juat Chin Foo,
Hong Yu Li,
Soumita Ghosh,
Heike Wollmann,
Amaury Cazenave-Gassiot,
Chee Bing Ong,
Markus R Wenk,
Weiping Han,
Hyungwon Choi,
Philipp Kaldis
eLife
4 Nov 2020
BMRC
Institute of Molecular and Cell Biology
Loss of hepatocyte cell division leads to liver inflammation and fibrosis
Matthew R. Dewhurst,
Jin Rong Ow,
Gözde Zafer,
Noémi K. M. van Hul,
Heike Wollmann,
Xavier Bisteau,
David Brough,
Hyungwon Choi,
Philipp Kaldis
PLOS Genetics
18 May 2020
BMRC
Institute of Molecular and Cell Biology
BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
Larry Sai Weng Loo,
Andreas Alvin Purnomo Soetedjo,
Hwee Hui Lau,
Natasha Hui Jin Ng,
Soumita Ghosh,
Linh Nguyen,
Vidhya Gomathi Krishnan,
Hyungwon Choi,
Xavier Roca,
Shawn Hoon,
Adrian Kee Keong Teo
Cell Death & Disease
13 Nov 2019
BMRC
Bioinformatics Institute
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype
Joanna Niska-Blakie,
Lakshmi Gopinathan,
Kia Ngee Low,
Yang Lay Kien,
Christine M. F. Goh,
Matias J. Caldez,
Elisabeth Pfeiffenberger,
Oliver S. Jones,
Chee Bing Ong,
Igor V. Kurochkin,
Vincenzo Coppola,
Lino Tessarollo,
Hyungwon Choi,
Yoganathan Kanagasundaram,
Frank Eisenhaber,
Sebastian Maurer-Stroh,
Philipp Kaldis
Cellular and Molecular Life Sciences
1 Sep 2019
BMRC
Institute of Molecular and Cell Biology
Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics
Joe Wee Jian Ong,
Kai Sen Tan,
Siok Ghee Ler,
Jayantha Gunaratne,
Hyungwon Choi,
Ju Ee Seet,
Vincent Tak-Kwong Chow
Cells
9 Jul 2019
BMRC
Institute of Molecular and Cell Biology
iOmicsPASS: network-based integration of multiomics data for predictive subnetwork discovery
Hiromi W. L. Koh,
Damian Fermin,
Christine Vogel,
Kwok Pui Choi,
Rob M. Ewing,
Hyungwon Choi
NPJ Systems Biology and Applications
4 Jun 2019
BMRC
Institute of Molecular and Cell Biology
Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence
Wee Siong Chew,
Federico Torta,
Shanshan Ji,
Hyungwon Choi,
Husna Begum,
Xueling Sim,
Chin Meng Khoo,
Eric Yin Hao Khoo,
Wei-Yi Ong,
Rob M. Van Dam,
Markus R. Wenk,
E. Shyong Tai,
Deron R. Herr
JCI Insight
24 May 2019
BMRC
Institute of Molecular and Cell Biology
Exploiting Interdata Relationships in Next-generation Proteomics Analysis
Burcu Vitrinel,
Hiromi W. L. Koh,
Funda Mujgan Kar,
Shuvadeep Maity,
Justin Rendleman,
Hyungwon Choi,
Christine Vogel
Molecular and Cellular Proteomics
5 Apr 2019
BMRC
Institute of Molecular and Cell Biology
Plasma Protein and MicroRNA Biomarkers of Insulin Resistance: A Network-Based Integrative -Omics Analysis
Hyungwon Choi,
Hiromi W. L. Koh,
Lihan Zhou,
He Cheng,
Tze Ping Loh,
Ehsan Parvaresh Rizi,
Sue Anne Toh,
Gabriele V. Ronnett,
Bevan E. Huang,
Chin Meng Khoo
Frontiers in Physiology
14 Nov 2018
BMRC
Institute of Molecular and Cell Biology
Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures
Kai Sen Tan,
Yan Yan,
Wai Ling Hiromi Koh,
Liang Li,
Hyungwon Choi,
Thai Tran,
Richard Sugrue,
De Yun Wang,
Vincent T. Chow
Frontiers in Microbiology
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