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21 Dec 2020
BMRC
Institute of Molecular and Cell Biology
Remodelling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division
Jin Rong Ow,
Matias J Caldez,
Gözde Zafer,
Juat Chin Foo,
Hong Yu Li,
Soumita Ghosh,
Heike Wollmann,
Amaury Cazenave-Gassiot,
Chee Bing Ong,
Markus R Wenk,
Weiping Han,
Hyungwon Choi,
Philipp Kaldis
eLife
4 Nov 2020
BMRC
Institute of Molecular and Cell Biology
Loss of hepatocyte cell division leads to liver inflammation and fibrosis
Matthew R. Dewhurst,
Jin Rong Ow,
Gözde Zafer,
Noémi K. M. van Hul,
Heike Wollmann,
Xavier Bisteau,
David Brough,
Hyungwon Choi,
Philipp Kaldis
PLOS Genetics
17 Jul 2020
BMRC
Institute of Molecular and Cell Biology
Global translation during early development depends on the essential transcription factor PRDM10
Brenda Y. Han,
Michelle K.Y. Seah,
Imogen R. Brooks,
Delia H.P. Quek,
Dominic R. Huxley,
Chuan-Sheng Foo,
Li Ting Lee,
Heike Wollmann,
Huili Guo,
Daniel M. Messerschmidt,
Ernesto Guccione
Nature Communications
16 Apr 2020
BMRC
Institute of Molecular and Cell Biology
Infertility-Causing Haploinsufficiency Reveals TRIM28/KAP1 Requirement in Spermatogonia
Joel H. L. Tan,
Heike Wollmann,
Ans M.M. van Pelt,
Philipp Kaldis,
Daniel M. Messerschmidt
Stem Cell Reports
10 Jan 2020
BMRC
Institute of Molecular and Cell Biology
PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly
Slim Mzoughi,
Federico Di Tullio,
Diana H. P. Low,
Corina-Mihaela Motofeanu,
Sheena L. M. Ong,
Heike Wollmann,
Cheng Mun Wun,
Paul Kruszka,
Maximilian Muenke,
Friedhelm Hildebrandt,
N. Ray Dunn,
Daniel M. Messerschmidt,
Ernesto Guccione
Science Advances
26 Jul 2019
BMRC
Institute of Molecular and Cell Biology
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I
Philipp Kaldis,
Nathan Palmer,
S. Zakiah A. Talib,
Chandrahas Koumar Ratnacaram,
Diana Low,
Xavier Bisteau,
Joanna Hui Si Lee,
Elisabeth Pfeiffenberger,
Heike Wollmann,
Joel Heng Loong Tan,
Sheena Wee,
Radoslaw Sobota,
Jayantha Gunaratne,
Daniel M. Messerschmidt,
Ernesto Guccione
Journal of Cell Biology
10 Jul 2019
BMRC
Institute of Molecular and Cell Biology
The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.
Michelle K. Y. Seah,
Yaju Wang,
Pierre-Alexis Goy,
Hui Mun Loh,
Wen Jun Peh,
Diana H. P. Low,
Brenda Y. Han,
Esther Wong,
Ei Leen Leong,
Gernot Wolf,
Slim Mzoughi,
Heike Wollmann,
Todd S. Macfarlan,
Ernesto Guccione,
Daniel M. Messerschmidt
Development
7 Sep 2018
BMRC
Institute of Molecular and Cell Biology
MBNL1 alternative splicing isoforms play opposing roles in cancer
Tommaso Tabaglio,
Diana HP Low,
Winnie Koon Lay Teo,
Pierre Alexis Goy,
Piotr Cywoniuk,
Heike Wollmann,
Jessica Ho,
Damien Tan,
Joey Aw,
Andrea Pavesi,
Krzysztof Sobczak,
Dave Keng Boon Wee,
Ernesto Guccione
Life Science Alliance
24 Jul 2017
BMRC
Institute of Molecular and Cell Biology
PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK–ERK signaling
Slim Mzoughi,
Jingxian Zhang,
Delphine Hequet,
Shun Xie Teo,
Haitong Fang,
Qiao Rui Xing,
Marco Bezzi,
Michelle Kay Yi Seah,
Sheena L M Ong,
Eun Myoung Shin,
Heike Wollmann,
Esther S M Wong,
Muthafar Al-Haddawi,
Colin L Stewart,
Vinay Tergaonkar,
Yuin-Han Loh,
N Ray Dunn,
Daniel M Messerschmidt,
Ernesto Guccione
Nature Genetics
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