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29 Aug 2023
BMRC
Skin Research Lab
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis
Kim Samirah Robinson,
Gee Ann Toh,
Muhammad Jasrie Firdaus,
Khek Chian Tham,
Pritisha Rozario,
Chrissie K. Lim,
Ying Xiu Toh,
Zhi Heng Lau,
Sophie Charlotte Binder,
Jacob Mayer,
Carine Bonnard,
Florian I. Schmidt,
John E.A. Common,
Franklin L. Zhong
Journal of Experimental Medicine
9 Apr 2021
BMRC
Institute of Molecular and Cell Biology
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity
Cheryl Q. E. Lee,
Baptiste Kerouanton,
Sonia Chothani,
Shan Zhang,
Ying Chen,
Chinmay Kumar Mantri,
Daniella Helena Hock,
Radiance Lim,
Rhea Nadkarni,
Vinh Thang Huynh,
Daryl Lim,
Wei Leong Chew,
Franklin L. Zhong,
David Arthur Stroud,
Sebastian Schafer,
Vinay Tergaonkar,
Ashley L. St John,
Owen J. L. Rackham,
Lena Ho
Nature Communications
4 Sep 2019
BMRC
Institute of Molecular and Cell Biology
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis
Scott B. Drutman,
Filomeen Haerynck,
Franklin L. Zhong,
David Hum,
Nicholas J. Hernandez,
Serkan Belkaya,
Franck Rapaport,
Sarah Jill de Jong,
David Creytens,
Simon J. Tavernier,
Katrien Bonte,
Sofie De Schepper,
Jutte van der Werff ten Bosch,
Lazaro Lorenzo-Diaz,
Andy Wullaert,
Xavier Bossuyt,
Gérard Orth,
Vincent R. Bonagura,
Vivien Béziat,
Laurent Abel,
Emmanuelle Jouanguy,
Bruno Reversade,
Jean-Laurent Casanova
Proceedings of the National Academy of Sciences of the United States of America
9 Aug 2019
BMRC
Institute of Molecular and Cell Biology
Generation of four H1 hESC sublines carrying a hemizygous knock-out/mutant MECP2
Ruizhu Zenga,
Harwin Sidika,
Kim S. Robinson,
Franklin L. Zhong,
Bruno Reversade,
Mahmoud A. Pouladi
Stem Cell Research
5 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
Franklin L. Zhong,
Kim Robinson,
Daniel Eng Thiam Teo,
Kiat-Yi Tan,
Chrissie Lim,
Cassandra R. Harapas,
Chien-Hsiung Yu,
William H. Xie,
Radoslaw M. Sobota,
Veonice Bijin Au,
Richard Hopkins,
Andrea D'Osualdo,
John C. Reed,
John E. Connolly,
Seth L. Masters,
Bruno Reversade
Journal of Biological Chemistry
26 Nov 2018
BMRC
Institute of Molecular and Cell Biology
Structural basis of RIP2 activation and signaling
Qin Gong,
Ziqi Long,
Franklin L. Zhong,
Daniel Eng Thiam Teo,
Yibo Jin,
Zhan Yin,
Zhao Zhi Boo,
Yaming Zhang,
Jiawen Zhang,
Renliang Yang,
Shashi Bhushan,
Bruno Reversade,
Zongli Li,
Bin Wu
Nature Communications
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