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8 Nov 2013
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BMRC
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Institute of Medical Biology
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Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome (Pending publish)
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Ruenn Chai Lai,
Soon Sim Tan,
Bao Ju Teh,
Siu Kwan Sze,
Fatih Arslan,
Dominique P. de Kleijn,
Andre Choo,
Sai Kiang Lim
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International Journal of Proteomics
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14 Jan 2013
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BMRC
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Institute of Medical Biology
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Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury (Pending publish)
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Fatih Arslan,
Ruenn Chai Lai,
Mirjam B. Smeets,
Lars Akeroyd,
Andre Choo,
Eissa N.E. Aguor,
Leo Timmers,
Harold V. van Rijen,
Pieter A. Doevendans,
Gerard Pasterkamp,
Sai Kiang Lim,
Dominique P. de Kleijn
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Stem Cell Research
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6 Apr 2012
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BMRC
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Institute of Medical Biology
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Metabolic Adaptation to a Disruption in Oxygen Supply during Myocardial Ischemia and Reperfusion Is Underpinned by Temporal and Quantitative Changes in the Cardiac Proteome (Pending publish)
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Xin Li,
Fatih Arslan,
Yan Ren,
Sunil S. Adav,
Kian Keong Poh,
Vitaly Sorokin,
Chuen Neng Lee,
Dominique De Kleijn,
Sai Kiang Lim,
Siu Kwan Sze
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Journal of Proteome Research
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25 Apr 2011
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BMRC
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Institute of Medical Biology
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Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs
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Soon Sim Tan,
Ruenn Chai Lai,
Andre Boon Hwa Choo,
Jayanthi Padmanabhan,
Chuen Neng Lee,
Tian Sheng Chen,
Fatih Arslan,
Yijun Yin,
Dominique PV de Kleijn,
Sai Kiang Lim
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Journal of Translational Medicine
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28 Jan 2011
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BMRC
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Institute of Medical Biology
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Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction (Pending publish)
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Andree Choo,
Jan J. Piek,
Pieter A. Doevendans,
Gerard Pasterkamp,
Dominique P.V. de Kleijn,
Leo Timmers,
Sai Kiang Lim,
Imo E. Hoefer,
Fatih Arslan,
Ruenn Chai Lai,
Angelique A.M. van Oorschot,
Marie Jose Goumans,
Chaylendra Strijder,
Sui Kwan Sze
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Stem Cell Research
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4 Jan 2010
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BMRC
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Institute of Medical Biology
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Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury (Pending publish)
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Chuen Neng Lee,
Reida Menshawe El Oakley,
Gerard Pasterkamp,
Dominique P.V. de Kleijn,
Sai Kiang Lim,
Ruenn Chai Lai,
Fatih Arslan,
May May Lee,
Newman Siu Kwan Sze,
Andre Choo,
Tian Sheng Chen,
Manuel Salto-Tellez,
Leo Timmers
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Stem Cell Research
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8 Mar 2008
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BMRC
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Institute of Medical Biology
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Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium (Pending publish)
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Leo Timmers,
Sai Kiang Lim,
Fatih Arslan,
Jeffrey S. Armstrong,
Imo E. Hoefer,
Pieter A. Doevendans,
Jan J. Piek,
Reida Menshawe El Oakley,
Andre Choo,
Chuen Neng Lee,
Gerard Pasterkamp,
Dominique P.V. de Kleijn
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Stem Cell Research
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