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26 Jun 2019
BMRC
Bioinformatics Institute
A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice
Kitti Wing Ki Chan,
Satoru Watanabe,
Jocelyn Y. Jin,
Julien Pompon,
Don Teng,
Sylvie Alonso,
Dhanasekaran Vijaykrishna,
Scott B. Halstead,
Jan K. Marzinek,
Peter J. Bond,
Bo Burla,
Federico Torta,
Markus R. Wenk,
Eng Eong Ooi,
Subhash G. Vasudevan
Science Translational Medicine
29 Mar 2019
BMRC
Bioinformatics Institute
Structure mapping of dengue and Zika viruses reveals functional long-range interactions
Roland G. Huber,
Xin Ni Lim,
Wy Ching Ng,
Adelene Y. L. Sim,
Hui Xian Poh,
Yang Shen,
Su Ying Lim,
Karin B. Sundstrom,
Xuyang Sun,
Jong Ghut Aw,
Horng Khit Too,
Peng Hee Boey,
Andreas Wilm,
Tanu Chawla,
Milly M. Choy,
Lu Jiang,
Paola Florez De Sessions,
Xian Jun Loh,
Sylvie Alonso,
Martin Hibberd,
Niranjan Nagarajan,
Eng Eong Ooi,
Peter J. Bond,
October M. Sessions,
Wan Yue
Nature Communications
20 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine
David A. G. Skibinski,
Leigh Ann Jones,
Yuan O. Zhu,
Lin Wu Xue,
Bijin Au,
Bernett Lee,
Ahmad Nazri Mohamed Naim,
Audrey Lee,
Nivashini Kaliaperumal,
Jenny G. H. Low,
Lawrence S. Lee,
Michael Poidinger,
Philippe Saudan,
Martin Bachmann,
Eng Eong Ooi,
Brendon J. Hanson,
Veronica Novotny-Diermayr,
Alex Matter,
Anna-Marie Fairhurst,
Martin L. Hibberd,
John E. Connolly
Scientific Reports
3 May 2017
BMRC
Institute of Molecular and Cell Biology
Serum Metabolomics Investigation of Humanized Mouse Model of Dengue Virus Infection
Liang Cui,
Jue Hou,
Jinling Fang,
Yie Hou Lee,
Vivian Vasconcelos Costa,
Lan Hiong Wong,
Qingfeng Chen,
Eng Eong Ooi,
Steven R. Tannenbaum,
Jianzhu Chen,
Choon Nam Ong
Journal of Virology
9 Oct 2015
BMRC
Institute of Molecular and Cell Biology
Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness
Gayathri Manokaran,
Esteban Finol,
Chunling Wang,
Jayantha Gunaratne,
Justin Bahl,
Eugenia Z. Ong,
Hwee Cheng Tan,
October M. Sessions,
Alex M. Ward,
Duane J. Gubler,
Eva Harris,
Mariano A. Garcia-Blanco,
Eng Eong Ooi
Science
18 Jul 2014
BMRC
Institute of Molecular and Cell Biology
Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers
Lawrence S. Lee,
Jenny G.H. Low,
Eng Eong Ooi,
Kantharaj Ethirajulu,
Pauline Yeo,
Alex Matter,
John E. Connolly,
David A.G. Skibinski,
Philippe Saudan,
Martin Bachmann,
Brendon J. Hanson,
Qingshu Lu,
Sebastian Maurer-Stroh,
Sam Lim,
Veronica Novotny-Diermayr
Vaccine
22 Dec 2011
BMRC
Singapore Immunology Network
Dengue Virus Activates Polyreactive, Natural IgG B Cells after Primary and Secondary Infection
Yee Sin Leo,
Feng Gu,
Marie Flamand,
Shamala Devi,
Mickey B. Koh,
Martin L. Hibberd,
Eng Eong Ooi,
Jenny G. Low,
Thavamalar Balakrishnan,
Dennis B. Bela-Ong,
Ying Xiu Toh,
Katja Fink,
Xia Jin
PLoS ONE
2 Aug 2011
BMRC
Genome Institute of Singapore
Characterization of early host responses in adults with dengue disease
Anna Lindblom,
Mark J Schreiber,
Ling Ling,
Angelia Chow,
Martin L Hibberd,
Thomas Tolfvenstam,
Eng Eong Ooi
BMC Infectious Diseases
19 Aug 2010
BMRC
Singapore Institute for Clinical Sciences
Contribution of Herpesvirus Specific CD8 T Cells to Anti-Viral T Cell Response in Humans
Elena Sandalova,
Diletta Laccabue,
Carolina Boni,
Anthony T. Tan,
Katja Fink,
Eng Eong Ooi,
Robert Chua,
Bahar Shafaeddin Schreve,
Carlo Ferrari,
Antonio Bertoletti,
Liisa Selin
PLoS Pathogens
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