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1 Oct 2021
BMRC
Skin Research Lab
A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex
Tong San Tan,
John E. A. Common,
John S. Y. Lim,
Cedric Badowski,
Muhammad Jasrie Firdaus,
Steven S. Leonardi,
E. Birgitte Lane
Journal of Cell Science
20 Feb 2020
BMRC
Skin Research Institute of Singapore
Belinostat Resolves Skin Barrier Defects in Atopic Dermatitis by Targeting the Dysregulated miR-335:SOX6 Axis
Wen Chiy Liew,
Gopinath M. Sundaram,
Shan Quah,
Guo Guang Lum,
Jonathan S. L. Tan,
Rajkumar Ramalingam,
John E. A. Common,
Mark B. Y. Tang,
E. Birgitte Lane,
Steven Tien Guan Thng,
Prabha Sampath
The Journal of Allergy and Clinical immunology
19 Oct 2017
BMRC
Skin Research Lab
Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants
(Pending publish)
X.F. Colin C. Wong,
Simon L.I.J. Denil,
Jia Nee Foo,
Huijia Chen,
Angeline Su Ling Tay,
Rebecca L. Haines,
Mark B.Y. Tang,
W.H. Irwin McLean,
Aileen Sandilands,
Frances J.D. Smith,
E. Birgitte Lane,
Jianjun Liu,
John E.A. Common
Journal of Allergy and Clinical Immunology
20 Feb 2017
BMRC
Skin Research Lab
A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
Dilip Kumar,
Kia Joo Puan,
Anand Kumar Andiappan,
Bernett Lee,
Geertje H. A. Westerlaken,
Doreen Haase,
Rossella Melchiotti,
Zhuang Li,
Nurhashikin Yusof,
Josephine Lum,
Geraldine Koh,
Shihui Foo,
Joe Yeong,
Alexessander Couto Alves,
Juha Pekkanen,
Liang Dan Sun,
Astrid Irwanto,
Benjamin P. Fairfax,
Vivek Naranbhai,
John E. A. Common,
Mark Tang,
Chin Keh Chuang,
Marjo-Riitta Jarvelin,
Julian C. Knight,
Xuejun Zhang,
Fook Tim Chew,
Shyam Prabhakar,
Liu Jianjun,
De Yun Wang,
Francesca Zolezzi,
Michael Poidinger,
E. Birgitte Lane,
Linde Meyaard,
Olaf Rotzschke
Genome Medicine
12 Jul 2016
BMRC
Skin Research Lab
Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare
(Pending publish)
Kern Rei Chng,
Angeline Su Ling Tay,
Chenhao Li,
Amanda Hui Qi Ng,
Jingjing Wang,
Bani Kaur Suri,
Sri Anusha Matta,
Naomi McGovern,
Baptiste Janela,
Xuan Fei Colin C. Wong,
Yang Yie Sio,
Bijin Veonice Au,
Andreas Wilm,
Paola Florez De Sessions,
Thiam Chye Lim,
Mark Boon Yang Tang,
Florent Ginhoux,
John E. Connolly,
E. Birgitte Lane,
Fook Tim Chew,
John E. A. Common,
Niranjan Nagarajan
Nature Microbiology
6 Jan 2016
BMRC
Skin Research Lab
Assays to Study Consequences of Cytoplasmic Intermediate Filament Mutations
(Pending publish)
Tong San Tan,
Yi Zhen Ng,
Cedric Badowski,
Tram Dang,
John E.A. Common,
Lukas Lacina,
Ildiko Szeverenyi,
E. Birgitte Lane
Methods in Enzymology
9 Oct 2014
BMRC
Institute of Medical Biology
Making more matrix: Enhancing the deposition of dermal-epidermal junction components in vitro and accelerating organotypic skin culture development, using macromolecular crowding.
Paula Benny,
Cedric Badowski,
E. Birgitte Lane,
Michael Raghunath
Tissue Engineering Part A
10 Jul 2014
BMRC
Institute of Medical Biology
Characterization of fetal keratinocytes, showing enhanced stem cell-like properties: a potential source of cells for skin reconstruction
Kenneth K.B. Tan,
Giorgiana Salgado,
John E. Connolly,
Jerry K.Y. Chan,
E. Birgitte Lane
Stem Cell Reports
30 Mar 2013
BMRC
Skin Research Lab
Fabrication of a 3D hair follicle‐like hydrogel by soft lithography
(Pending publish)
Jing Pan,
Sui Yung Chan,
John E. A. Common,
Shahrouz Amini,
Ali Miserez,
E. Birgitte Lane,
Lifeng Kang
Journal of Biomedical Materials Research Part A
25 Feb 2013
BMRC
Skin Research Lab
Lamin B1 fluctuations have differential effects on cellular proliferation and senescence
(Pending publish)
Oliver Dreesen,
Alexandre Chojnowski,
Peh Fern Ong,
Tian Yun Zhao,
John E. Common,
Declan Lunny,
E. Birgitte Lane,
Shu Jin Lee,
Leah A. Vardy,
Colin L. Stewart,
Alan Colman
Journal of Cell Biology
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