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26 Apr 2018
BMRC
Bioprocessing Technology Institute
Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells
Filip Laco,
Tsung Liang Woo,
Qixing Zhong,
Radoslaw Szmyd,
Sherwin Ting,
Fahima Jaleel Khan,
Christina L. L. Chai,
Shaul Reuveny,
Allen Chen,
Steve Oh
Stem Cell Reports
18 Dec 2014
BMRC
Bioprocessing Technology Institute
Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling
Filip Laco,
Joo-Leng Low,
Jasmin Seow,
Tsung Liang Woo,
Qixing Zhong,
Jayasree Seayad,
Zhenfeng Liu,
Heiming Wei,
Shaul Reuveny,
David A. Elliott,
Christina L. L. Chai,
Steve K. W. Oh
Journal of Molecular and Cellular Cardiology
13 Dec 2014
SERC
Institute of Chemical and Engineering Sciences
An amidation/cyclization approach to the synthesis of N-hydroxyquinolinones and their biological evaluation as potential anti-plasmodial, anti-bacterial, and iron(II)-chelating agents
Mun Hong Ngai,
Rajavel Srinivasan,
Alice Soh Meoy Ong,
Christina L. L. Chai,
Yanbo Teng,
Rossarin Suwanarusk,
Bow Ho,
Laurent Renia
Bioorganic & Medicinal Chemistry Letters
15 Oct 2014
SERC
Institute of Chemical and Engineering Sciences
3-Deazaneplanocin A and Neplanocin A analogues and their effects on apoptotic cell death
Eric K. W. Tam,
Tuan Minh Nguyen,
Cheryl Z. H. Lim,
Puay Leng Lee,
Zhimei Li,
Xia Jiang,
Sridhar Santhanakrishnan,
Tiong Wei Tan,
Yi Ling Goh,
Sze Yue Wong,
Haiyan Yang,
Esther H. Q. Ong,
Jeffrey Hill,
Qiang Yu,
Christina L. L. Chai
ChemMedChem
12 Oct 2014
SERC
Institute of Chemical and Engineering Sciences
Design, synthesis and biological evaluation of FLT3 covalent inhibitors with a resorcylic acid core
Christina L. L. Chai,
Jin Xu,
Esther H.Q. Ong,
Jeffrey Hill,
Anqi Chen
Bioorganic & Medicinal Chemistry
30 Sep 2014
SERC
Institute of Chemical and Engineering Sciences
Synthesis and biological studies of a triazole analogue of resorcylic acid lactone LL-Z1640-2
Wendy Y. L. Goh,
Christina L. L. Chai,
Anqi Chen
European Journal of Organic Chemistry
8 Aug 2013
SERC
Institute of Chemical and Engineering Sciences
Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor
Vanessa Joanne Xavier,
Jin Xu,
Anqi Chen,
Joma Joy,
Esther H. Q. Ong,
Jeffrey Hill,
Christina L. L. Chai
ChemMedChem
24 Jan 2011
SERC
Institute of Chemical and Engineering Sciences
Narrow disperse polymers using amine functionalized dithiobenzoate RAFT agent and easy removal of thiocarbonyl end group from the resultant polymers
Satyasankar Jana,
Anbanandam Parthiban,
Christina L. L. Chai
Journal of Polymer Science Part A: Polymer Chemistry
18 Feb 2010
SERC
Institute of Chemical and Engineering Sciences
Controlled synthesis and functionalization of PEGylated methacrylates bearing cyclic carbonate pendant groups
Satyasankar Jana,
Han Yu,
Anbanandam Parthiban,
Christina L. L. Chai
Journal of Polymer Science Part A: Polymer Chemistry
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