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19 Jul 2022 Others Experimental Drug Development Centre A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir Subramanyam Vankadara, Monique Danielle Dawson, Jia Yi Fong, Qin Yao Oh, Qi An Ang, Boping Liu, Hong Yun Chang, Judice Koh, Xiaoying Koh, Qian Wen Tan, Joma Joy, Cheng San Brian Chia ACS Medicinal Chemistry Letters
23 Mar 2021 Others Experimental Drug Development Centre Designing a leucine‐rich antibacterial nonapeptide with potent activity against mupirocin‐resistant MRSA via a structure–activity relationship study Qi An Ang, Giovinna Arfan, Chu Yang Fann Ong, Fui Mee Ng, Esther H. Q. Ong, Cheng San Brian Chia Chemical Biology & Drug Design
13 Aug 2018 Others Experimental Drug Development Centre Designing an ultra-short antibacterial peptide with potent activity against Mupirocin-resistant MRSA Giovinna Arfan, Chu Yang Fann Ong, Siew Mei Samantha Ng, Qiu Ying Lau, Fui Mee Ng, Esther Hong Qian Ong, Jeffrey Hill, Cheng San Brian Chia Chemical Biology & Drug Design
5 Jul 2018 Others Experimental Drug Development Centre Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide Bee Hui Liu, Chacko Jobichen, Cheng San Brian Chia, Tim Hon Man Chan, Jing Ping Tang, Theodora Chung, Jia Li, Anders Poulsen, Alvin W. Hung, Xiaoying Koh-Stenta, Yaw Sing Tan, Chandra S. Verma, Hong Kee Tan, Chan-shuo Wu, Feng Li, Jeffrey Hill, Joma Joy, Henry Yang, Li Chai, J. Sivaraman, Daniel G. Tenen PNAS
11 May 2018 BMRC Bioinformatics Institute Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH2 Qiu Ying Lau, Jianguo Li, Marc-Antoine Sani, Sheetal Sinha, Yan Li, Fui Mee Ng, CongBao Kang, Surajit Bhattacharjya, Frances Separovic, Chandra Verma, Cheng San Brian Chia Biochimica et Biophysica Acta (BBA) - Biomembranes
22 Jan 2018 Others Experimental Drug Development Centre Identification of an ultra-short peptide with potent Pseudomonas aeruginosa activity for development as a topical antibacterial agent Roland Jureen, Jeffrey Hill, Cheng San Brian Chia, Shu Wei Teo, Yaqing Elena Yong, Siew Mei Samantha Ng, Fui Mee Ng, Jeanette Teo International Journal of Peptide Research and Therapeutics
11 Jul 2017 Others Experimental Drug Development Centre Preliminary investigations into developing all-D Omiganan for treating Mupirocin-resistant MRSA skin infections Siew Mei Samantha Ng, Shu Wei Teo, Yaqing Elena Yong, Fui Mee Ng, Qiu Ying Lau, Roland Jureen, Jeffrey Hill, Cheng San Brian Chia Chemical Biology and Drug Design
22 Oct 2015 BMRC Institute of Molecular and Cell Biology Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy Guo-Ying Chen, CongBao Kang, Cheng San Brian Chia, Xuelian Luo, Wanjin Hong, Anders Poulsen, Ajaybabu V. Pobbati, Xiao Han, Alvin W. Hung, Seetoh Weiguang, Nur Huda Structure
9 Oct 2015 Others Experimental Drug Development Centre An FDA-drug library screen for compounds with bioactivities against meticillin-resistant Staphylococcus aureus (MRSA). Qiu Ying Lau, Yoke Yan Fion Tan, Vanessa Chai Yin Goh, David Jing Qin Lee, Fui Mee Ng, Esther H. Q. Ong, Jeffrey Hill, Cheng San Brian Chia Antibiotics
24 Jun 2015 Others Experimental Drug Development Centre Application of Fragment-Based Drug Discovery against DNA Gyrase B Cheng San Brian Chia, Qiu Ying Lau, Jeffrey Hill, Alvin Hung, Thomas Keller, Siew Wen Then, Nur Huda Ahmad, Ying Lei Wong, Hui Qi Ng, Guo-Ying Chen, Fui Mee Ng, Yih Wan Tan, Anders Poulsen, Wei Guang Seetoh, Grace Lin, CongBao Kang ChemPlusChem