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21 Jul 2024
BMRC
Genome Institute of Singapore
PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression
Yi Fei Lee,
Cheryl Zi Jin Phua,
Ju Yuan,
Bin Zhang,
May Yin Lee,
Srinivasaraghavan Kannan,
Yui Hei Jasper Chiu,
Casslynn Wei Qian Koh,
Choon Kong Yap,
Edwin Kok Hao Lim,
Jianbin Chen,
Yuhua Lim,
Jane Jia Hui Lee,
Anders Jacobsen Skanderup,
Zhenxun Wang,
Weiwei Zhai,
Nguan Soon Tan,
Chandra S. Verma,
Yvonne Tay,
Daniel Shao Weng Tan,
Wai Leong Tam
Genome Medicine
15 Feb 2024
BMRC
Bioinformatics Institute
Coarse-Grained Model of Glycosaminoglycans for Biomolecular Simulations
Aishwary T. Shivgan,
Jan K. Marzinek,
Alexander Krah,
Paul Matsudaira,
Chandra S. Verma,
Peter J. Bond
Journal of Chemical Theory and Computation
31 Oct 2023
BMRC
Singapore Immunology Network
DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11
Jia Tong Loh,
Joey Kay Hui Teo,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Anand Kumar Andiappan,
Hong-Hwa Lim,
Kong-Peng Lam
Science Signaling
14 Sep 2023
BMRC
Bioinformatics Institute
Elucidating the Effect of Polyethylene Terephthalate Chain Structure on Its Enzymatic Degradation Behavior
Jean-Baptiste Lena,
Rui A. Gonçalves,
Sharad Kharel,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Keerthi Mohan Pinchi,
Sierin Lim,
Yeng Ming Lam
ACS Sustainable Chemistry & Engineering
13 May 2023
BMRC
Bioinformatics Institute
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays
Stephen H. Kasper,
Stephanie Otten,
Brian Squadroni,
Cionna Orr‐Terry,
Yi Kuang,
Lily Mussallem,
Lan Ge,
Lin Yan,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Christopher J. Brown,
Charles W. Johannes,
David P. Lane,
Arun Chandramohan,
Anthony W. Partridge,
Lee R. Roberts,
Hubert Josien,
Alex G. Therien,
Erik C. Hett,
Bonnie J. Howell,
Andrea Peier,
Xi Ai,
Jason Cassaday
Bioengineering & Translational Medicine
13 Jan 2023
BMRC
Bioinformatics Institute
Designer co-beta-peptide copolymer selectively targets resistant and biofilm Gram-negative bacteria
Zhangyong Si,
Jianguo Li,
Lin Ruan,
Sheethal Reghu,
Ying Jie Ooi,
Peng Li,
Yabin Zhu,
Paula T. Hammond,
Chandra S. Verma,
Guillermo C. Bazan,
Kevin Pethe,
Mary B. Chan-Park
Biomaterials
11 May 2020
BMRC
Bioinformatics Institute
Macrocyclization of an all-D linear α-helical peptide imparts cellular permeability
Srinivasaraghavan Kannan,
Pietro G. A. Aronica,
Simon Ng,
Dawn Thean Gek Lian,
Yuri Frosi,
Sharon Chee,
Shimin Jiang,
Tsz Ying Yuen,
Ahmad Sadruddin,
Hung Yi Kristal Kaan,
Arun Chandramohan,
Yi Han,
Jin Huei Wong,
Yaw Sing Tan,
Zi Wei Chang,
Fernando Jose Ferrer-Gago,
Prakash Arumugam,
Shiying Chen,
Laurent Claude Stephane Renia,
Christopher J. Brown,
Charles W. Johannes,
Brian Henry,
David P. Lane,
Tomi K Sawyer,
Chandra S. Verma,
Anthony William Patridge
Chemical Science
10 May 2020
BMRC
Bioinformatics Institute
Extending the Martini coarse-grained forcefield to N-glycans
Aishwary T. Shivgan,
Jan K. Marzinek,
Roland G. Huber,
Alexander Krah,
Richard H. Henchman,
Paul Matsudaira,
Chandra S. Verma,
Peter J. Bond
bioRxiv
5 May 2020
BMRC
Bioinformatics Institute
De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits
Simon Ng,
Yu-Chi Juang,
Arun Chandramohan,
Hung Yi Kristal Kaan,
Ahmad Sadruddin,
Tsz Ying Yuen,
Fernando J. Ferrer-Gago,
Xue'Er Cheryl Lee,
Liew Xi,
Charles W. Johanes,
Christopher J. Brown,
Srinivasaraghavan Kanan,
Pietro G. Aronica,
Nils A. Berglund,
Chandra S. Verma,
Lijuan Liu,
Alexander Stoeck,
Tomi K. Sawyer,
Anthony W. Partridge,
David P. Lane
ACS Medicinal Chemistry Letters
29 Apr 2020
BMRC
Bioinformatics Institute
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation
Li Ren Kong,
Richard Weijie Ong,
Tua Zea Tan,
Nur Afiqah Binte Mohamed Salleh,
Matan Thangavelu,
Jane Vin Chan,
Lie Yong Judice Koh,
Giridharan Periyasamy,
Jieying Amelia Lau,
Thi Bich Uyen Le,
Lingzhi Wang,
Miyoung Lee,
Srinivasaraghavan Kannan,
Chandra S. Verma,
Chwee Ming Lim,
Wee Joo Chng,
David P. Lane,
Ashok Venkitaraman,
Huynh The Hung,
Chit Fang Cheok,
Boon Cher Goh
Nature Communications
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