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24 Apr 2020 BMRC Bioinformatics Institute Increased Protein S-Glutathionylation in Leber’s Hereditary Optic Neuropathy (LHON) James Chun Yip Chan, Stephanie Chupin, Lei Zhou, Naïg Gueguen, Valérie Desquiret-Dumas, Siew Kwan Koh, Jianguo Li, Yao Gan, Lu Deng, Chandra Verma, Roger W. Beuerman, Dan Milea, Eric Chun Yong Chan Chan, Pascal Reynier
24 Apr 2020 BMRC Skin Research Institute of Singapore Increased Protein S-Glutathionylation in Leber’s Hereditary Optic Neuropathy (LHON) Lei Zhou, James Chun Yip Chan, Stephanie Chupin, Naïg Gueguen, Valérie Desquiret-Dumas, Siew Kwan Koh, Jianguo Li, Yan Gao, Lu Deng, Chandra Verma, Roger W. Beuerman, Eric Chun Yong Chan, Dan Milea, Pascal Reynier
7 Jan 2019 BMRC Bioinformatics Institute Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein Christopher J. Brown, Chandra Verma, Serge Auvin, Dilraj Lama, Anne-Marie Liberatore, Yuri Frosi, Jessica Nakhle, Natia Tsomaia, Tarig Bashir, David P. Lane
13 Jul 2018 BMRC Bioinformatics Institute Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity James Chun Yip Chan, Alex Cheow Khoon Soh, Dorinda Yan Qin Kioh, Jianguo Li, Chandra Verma, Siew Kwan Koh, Roger Wilmer Beuerman, Lei Zhou, Eric Chun Yong Chan
21 Jun 2018 BMRC Bioinformatics Institute Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
16 May 2018 BMRC Institute of Molecular and Cell Biology Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
16 May 2018 BMRC Bioinformatics Institute Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket Srinivasaraghavan Kannan, Gireedhar Venkatachalam, Hong Hwa Lim, Uttam Surana, Chandra Verma
11 May 2018 BMRC Bioinformatics Institute Elucidating the bactericidal mechanism of action of the linear antimicrobial tetrapeptide BRBR-NH2 Qiu Ying Lau, Jianguo Li, Marc-Antoine Sani, Sheetal Sinha, Yan Li, Fui Mee Ng, CongBao Kang, Surajit Bhattacharjya, Frances Separovic, Chandra Verma, Cheng San Brian Chia
27 Apr 2018 BMRC Bioinformatics Institute Comparison of Charge Derivation Methods Applied to Amino Acid Parameterization Pietro G. A. Aronica, Stephen J. Fox, Chandra Verma
25 Apr 2018 BMRC Bioinformatics Institute Stapled peptides as a new technology to investigate protein-protein interactions in human platelets Jessica Iegre, Niaz S. Ahmed, Josephine S. Gaynord, Yuteng Wu, Kara M. Herlihy, Yaw Sing Tan, Maria E. Lopes-Pires, Rupam Jha, Yu Heng Lau, Hannah F. Sore, Chandra Verma, Daniel H. O' Donovan, Nicholas Pugh, David R. Spring
25 Apr 2018 BMRC Bioinformatics Institute Stapled peptides as a new technology to investigate protein-protein interactions in human platelets Jessica Legre, Niaz S. Ahmed, Josephine S. Gaynord, Yuteng Wu, Kara M. Herlihy, Yaw Sing Tan, Maria E. Lopes-Pires, Rupam Jha, Yu Heng Lau, Hannah F. Sore, Chandra Verma, Daniel H. O'Donovan, Nicholas Pugh, David R. Spring
13 Mar 2018 BMRC Bioinformatics Institute The effect of molecular shape on oligomerization of hydrophobic drugs: Molecular simulations of ciprofloxacin and nutlin Jianguo Li, Roger Beuerman, Chandra Verma
1 Jun 2017 BMRC Institute of Molecular and Cell Biology Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches Siew Kim Joyce Tan, Chandra Verma, Hung Yi Kristal Kaan, Adelene Y. L. Sim, Haiwei Song
2 Dec 2016 BMRC Bioinformatics Institute Palmitoylation of caspase-6 by HIP14 regulates its activation Niels H Skotte, Shaun S Sanders, Roshni R Singaraja, Dagmar E Ehrnhoefer, Kuljeet Vaid, Xiaofan Qiu, Srinivasaragavan Kannan, Chandra Verma, Michael R Hayden
28 Sep 2016 BMRC Bioinformatics Institute Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens Jia Wei Siau, Cynthia R. Coffill, Weiyun Villien Zhang, Yaw Sing Tan, Juliane Hundt, David Lane, Chandra Verma, Farid Ghadessy
14 Sep 2016 BMRC Bioinformatics Institute Topology independent comparison of RNA 3D structures using the CLICK algorithm Minh N. Nguyen, Adelene Y. L. Sim, Yue Wan, M. S. Madhusudhan, Chandra Verma
7 Jul 2016 BMRC Bioinformatics Institute Pushing the Envelope: Dengue Viral Membrane Coaxed into Shape by Molecular Simulations Jan K. Marzinek, Daniel A. Holdbrook, Roland G. Huber, Chandra Verma, Peter J. Bond
4 Apr 2016 BMRC Bioinformatics Institute Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides Siau Jia Wei, Sharon Chee, Larisa Yurlova, David Lane, Chandra Verma, Christopher Brown, Farid Ghadessy
20 Jan 2016 BMRC Bioinformatics Institute Characterizing the Conformational Landscape of Flavivirus Fusion Peptides via Simulation and Experiment Jan K. Marzinek, Rajamani Lakshminarayanan, Eunice Goh, Roland G. Huber, Sadhana Panzade, Chandra Verma, Peter J. Bond
28 Oct 2015 BMRC Bioinformatics Institute Mussel adhesion is dictated by time-regulated secretion and molecular conformation of mussel adhesive proteins Luigi Petrone, Akshita Kumar, Clarinda N. Sutanto, Navinkumar J. Patil, Srinivasaraghavan Kannan, Alagappan Palaniappan, Shahrouz Amini, Bruno Zappone, Chandra Verma, Ali Miserez
10 Jan 2015 BMRC Bioinformatics Institute A novel fragment based strategy for membrane active antimicrobials against MRSA Jianguo Li, Shouping Liu, Jun-Jie Koh, Hanxun Zou, Rajamani Lakshminarayanan, Yang Bai, Konstantin Pervushin, Lei Zhou, Chandra Verma, Roger W. Beuerman
12 Nov 2014 BMRC Bioinformatics Institute Rclick: a web server for comparison of RNA 3D structures Minh N. Nguyen, Chandra Verma
10 Mar 2014 BMRC Bioinformatics Institute Functionalised staple linkages for modulating the cellular activity of stapled peptides Yu Heng Lau, Peterson de Andrade, Soo-Tng Quah, Maxim Rossmann, Luca Laraia, Niklas Skold, Tze Jing Sum, Pamela J.E. Rowling, Thomas L. Joseph, Chandra Verma, Marko Hyvonen, Laura S. Itzhaki, Ashok R. Venkitaraman, Christopher J. Brown, David P. Lane, David R. Spring
13 Dec 2013 BMRC Bioinformatics Institute Rational optimization of conformational effects induced by hydrocarbon staples in peptides and their binding interfaces Dilraj Lama, Soo Tng Quah, Chandra Verma, Rajamani Lakshminarayanan, Roger Beuerman, David P. Lane, Christopher Brown
1 Dec 2013 BMRC Bioinformatics Institute A comparison and optimization of methods and factors affecting the transformation of Escherichia coli. Weng Tat Chan, Chandra Verma, David P. Lane, Samuel Gan
20 Nov 2013 BMRC Bioinformatics Institute Inhibition of nutlin-resistant HDM2 mutants by stapled peptides Jia Wei Siau, Thomas Joseph, Sharon Chee, Ling Li, Larisa Yurlova, Kourosh Zolghadr, Christopher Brown, David P. Lane, Chandra Verma, Farid Ghadessy
12 Nov 2013 BMRC Bioinformatics Institute Mapping the Structural and Dynamical Features of Multiple p53 DNA Binding Domains: Insights into Loop 1 Intrinsic Dynamics Suryani Lukman, David P. Lane, Chandra Verma
14 Jul 2010 BMRC Institute of Medical Biology Why an A-Loop Phospho-Mimetic Fails to Activate PAK1: Understanding an Inaccessible Kinase State by Molecular Dynamics Simulations Yuen-Wai Ng, Devanathan Raghunathan, Perry M. Chan, Yohendran Baskaran, Derek J. Smith, Chung-Hung Lee, Chandra Verma, Ed Manser
1 Feb 2010 BMRC p53 Laboratory Mdm2 and p53 are highly conserved from placozoans to man David P. Lane, Chit Fang Cheok, Christopher Brown, Arumugam Madhumalar, Farid J. Ghadessy, Chandra Verma