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15 Jul 2022
BMRC
Skin Research Lab
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome
(Pending publish)
Kim S. Robinson,
Gee Ann Toh,
Pritisha Rozario,
Rae Chua,
Stefan Bauernfried,
Zijin Sun,
Muhammad Jasrie Firdaus,
Shima Bayat,
Rhea Nadkarni,
Zhi Sheng Poh,
Khek Chian Tham,
Cassandra R. Harapas,
Chrissie K. Lim,
Werncui Chu,
Celest W. S. Tay,
Kiat Yi Tan,
Tianyun Zhao,
Carine Bonnard,
Radoslaw Sobota,
John E. Connolly,
John Common,
Seth L. Masters,
Kaiwen W. Chen,
Lena Ho,
Bin Wu,
Veit Hornung,
Franklin L. Zhong
Science
5 Dec 2018
BMRC
Institute of Molecular and Cell Biology
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
Franklin L. Zhong,
Kim Robinson,
Daniel Eng Thiam Teo,
Kiat-Yi Tan,
Chrissie Lim,
Cassandra R. Harapas,
Chien-Hsiung Yu,
William H. Xie,
Radoslaw M. Sobota,
Veonice Bijin Au,
Richard Hopkins,
Andrea D'Osualdo,
John C. Reed,
John E. Connolly,
Seth L. Masters,
Bruno Reversade
Journal of Biological Chemistry
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